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Gene Expression Literature Summary
Symbol
Name
ID
Kmt5a
lysine methyltransferase 5A
MGI:1915206

8 matching records from 8 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.
Age E3 E4.5 E5.5 E7.5 E8.5 E9.5 E11.5 E13.5 E15.5 E18 P
Immunohistochemistry (section) 1 1 1 1 1 1
In situ RNA (section) 1
In situ RNA (whole mount) 1 1
In situ reporter (knock in) 1 1 1
Western blot 1 1 1
RT-PCR 1 1 1 2 1

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available
Kmt5a  lysine methyltransferase 5A   (Synonyms: 2410195B05Rik, PR-SET7, Setd8)
Results  Reference
4J:181779 Driskell I, Oda H, Blanco S, Nascimento E, Humphreys P, Frye M, The histone methyltransferase Setd8 acts in concert with c-Myc and is required to maintain skin. EMBO J. 2012 Feb 1;31(3):616-29
3*J:160012 Jerome-Majewska LA, Achkar T, Luo L, Lupu F, Lacy E, The trafficking protein Tmed2/p24beta(1) is required for morphogenesis of the mouse embryo and placenta. Dev Biol. 2010 May 1;341(1):154-66
1J:312811 Modzelewski AJ, Shao W, Chen J, Lee A, Qi X, Noon M, Tjokro K, Sales G, Biton A, Anand A, Speed TP, Xuan Z, Wang T, Risso D, He L, A mouse-specific retrotransposon drives a conserved Cdk2ap1 isoform essential for development. Cell. 2021 Oct 28;184(22):5541-5558.e22
1J:219210 Nikolaou KC, Moulos P, Chalepakis G, Hatzis P, Oda H, Reinberg D, Talianidis I, Spontaneous development of hepatocellular carcinoma with cancer stem cell properties in PR-SET7-deficient livers. EMBO J. 2015 Feb 12;34(4):430-47
1J:226978 Tateossian H, Morse S, Simon MM, Dean CH, Brown SD, Interactions between the otitis media gene, Fbxo11, and p53 in the mouse embryonic lung. Dis Model Mech. 2015 Dec 1;8(12):1531-42
3J:313616 Zhang F, Zhao X, Jiang R, Wang Y, Wang X, Gu Y, Xu L, Ye J, Chen CD, Guo S, Zhang D, Zhao D, Identification of Jmjd3 as an Essential Epigenetic Regulator of Hox Gene Temporal Collinear Activation for Body Axial Patterning in Mice. Front Cell Dev Biol. 2021;9:642931
2J:291677 Zheng W, Nazish J, Wahab F, Khan R, Jiang X, Shi Q, DDB1 Regulates Sertoli Cell Proliferation and Testis Cord Remodeling by TGFbeta Pathway. Genes (Basel). 2019 Nov 26;10(12)
6*J:338080 Zhou X, Xu Y, Ren S, Yang N, Sun Y, Yang Q, Zhang Y, Cai H, Deng W, Chen J, Chen D, Cao B, Qi H, Wang H, Lu J, Trophoblast PR-SET7 dysfunction induces viral mimicry response and necroptosis associated with recurrent miscarriage. Proc Natl Acad Sci U S A. 2023 Jun 20;120(25):e2216206120

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory