Symbol Name ID |
Ppp4r3a
protein phosphatase 4 regulatory subunit 3A MGI:1915984 |
Age | E11.5 | E12.5 | E14.5 | E15.5 | P |
Immunohistochemistry (section) | 1 | 1 | 3 | 1 | 1 |
In situ RNA (section) | 1 | ||||
Western blot | 2 | ||||
RT-PCR | 1 | 2 |
Ppp4r3a protein phosphatase 4 regulatory subunit 3A (Synonyms: 1110034C04Rik, Smek1) | |
Results | Reference |
1* | J:93300 Blackshaw S, Harpavat S, Trimarchi J, Cai L, Huang H, Kuo WP, Weber G, Lee K, Fraioli RE, Cho SH, Yung R, Asch E, Ohno-Machado L, Wong WH, Cepko CL, Genomic analysis of mouse retinal development. PLoS Biol. 2004 Oct;2(9):E247 |
2 | J:256509 Chang WH, Choi SH, Moon BS, Cai M, Lyu J, Bai J, Gao F, Hajjali I, Zhao Z, Campbell DB, Weiner LP, Lu W, Smek1/2 is a nuclear chaperone and cofactor for cleaved Wnt receptor Ryk, regulating cortical neurogenesis. Proc Natl Acad Sci U S A. 2017 Dec 12;114(50):E10717-E10725 |
1 | J:314283 Duan RN, Yang CL, Du T, Liu A, Wang AR, Sun WJ, Li X, Li JX, Yan CZ, Liu QJ, Smek1 deficiency exacerbates experimental autoimmune encephalomyelitis by activating proinflammatory microglia and suppressing the IDO1-AhR pathway. J Neuroinflammation. 2021 Jun 28;18(1):145 |
4 | J:317544 Lyu J, Kim HR, Yamamoto V, Choi SH, Wei Z, Joo CK, Lu W, Protein phosphatase 4 and Smek complex negatively regulate Par3 and promote neuronal differentiation of neural stem/progenitor cells. Cell Rep. 2013 Nov 14;5(3):593-600 |
3 | J:244773 Moon BS, Yun HM, Chang WH, Steele BH, Cai M, Choi SH, Lu W, Smek promotes corticogenesis through regulating Mbd3's stability and Mbd3/NuRD complex recruitment to genes associated with neurogenesis. PLoS Biol. 2017 May;15(5):e2001220 |
2* | J:123644 Roma G, Cobellis G, Claudiani P, Maione F, Cruz P, Tripoli G, Sardiello M, Peluso I, Stupka E, A novel view of the transcriptome revealed from gene trapping in mouse embryonic stem cells. Genome Res. 2007 Jul;17(7):1051-60 |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 10/29/2024 MGI 6.24 |
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