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Gene Expression Literature Summary
Symbol
Name
ID
Srrm4
serine/arginine repetitive matrix 4
MGI:1916205

6 matching records from 6 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.
Age E8.5 E9.5 E10.5 E11 E12 E12.5 E13.5 E14 E15 E16.5 E17 E17.5 E18 E18.5 E19 P
In situ RNA (section) 1 1 1 2
In situ RNA (whole mount) 1
In situ reporter (knock in) 1 1 1 1 1
Western blot 1 1 1 1 1 2 1
RT-PCR 1 2 3 1 1 3

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available
Srrm4  serine/arginine repetitive matrix 4   (Synonyms: 1500001A10Rik, B230202K19Rik, bv, flopsy, fp, mKIAA1853, nSR100)
Results  Reference
5*J:193641 Nakano Y, Jahan I, Bonde G, Sun X, Hildebrand MS, Engelhardt JF, Smith RJ, Cornell RA, Fritzsch B, Banfi B, A mutation in the Srrm4 gene causes alternative splicing defects and deafness in the Bronx waltzer mouse. PLoS Genet. 2012;8(10):e1002966
5*J:281311 Nakano Y, Wiechert S, Banfi B, Overlapping Activities of Two Neuronal Splicing Factors Switch the GABA Effect from Excitatory to Inhibitory by Regulating REST. Cell Rep. 2019 Apr 16;27(3):860-871.e8
1*J:249252 Quesnel-Vallieres M, Dargaei Z, Irimia M, Gonatopoulos-Pournatzis T, Ip JY, Wu M, Sterne-Weiler T, Nakagawa S, Woodin MA, Blencowe BJ, Cordes SP, Misregulation of an Activity-Dependent Splicing Network as a Common Mechanism Underlying Autism Spectrum Disorders. Mol Cell. 2016 Dec 15;64(6):1023-1034
11J:221584 Quesnel-Vallieres M, Irimia M, Cordes SP, Blencowe BJ, Essential roles for the splicing regulator nSR100/SRRM4 during nervous system development. Genes Dev. 2015 Apr 1;29(7):746-59
4J:215543 Raj B, Irimia M, Braunschweig U, Sterne-Weiler T, O'Hanlon D, Lin ZY, Chen GI, Easton LE, Ule J, Gingras AC, Eyras E, Blencowe BJ, A global regulatory mechanism for activating an exon network required for neurogenesis. Mol Cell. 2014 Oct 2;56(1):90-103
4*J:265602 Raj B, O'Hanlon D, Vessey JP, Pan Q, Ray D, Buckley NJ, Miller FD, Blencowe BJ, Cross-regulation between an alternative splicing activator and a transcription repressor controls neurogenesis. Mol Cell. 2011 Sep 2;43(5):843-50

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/19/2024
MGI 6.24
The Jackson Laboratory