Gene Expression Literature Summary

• Symbol: Med23
• Name: mediator complex subunit 23
• ID: MGI:1917458

8 matching records from 8 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.

Age	E7.5	E8.5	E9.5	E10.5	E12.5	E14.5	E15.5	E18.5	P
In situ RNA (section)						1
Immunohistochemistry (whole mount)			1
In situ RNA (whole mount)							1
In situ reporter (knock in)	1	1		1
Western blot		1	2	1	1				2
RT-PCR		1	2			1		1	1

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Med23  mediator complex subunit 23   (Synonyms: 3000002A17Rik, Crsp3, ESTM7, mKIAA1216, sno, Sur2, X83317)
Results	Reference
1	J:304767 Dash S, Bhatt S, Falcon KT, Sandell LL, Trainor PA, Med23 Regulates Sox9 Expression during Craniofacial Development. J Dent Res. 2021 Apr;100(4):406-414
5	J:299019 Dash S, Bhatt S, Sandell LL, Seidel CW, Ahn Y, Krumlauf RE, Trainor PA, The Mediator Subunit, Med23 Is Required for Embryonic Survival and Regulation of Canonical WNT Signaling During Cranial Ganglia Development. Front Physiol. 2020;11:531933
1*	J:153498 Diez-Roux G, Banfi S, Sultan M, Geffers L, Anand S, Rozado D, Magen A, Canidio E, Pagani M, Peluso I, Lin-Marq N, Koch M, Bilio M, Cantiello I, Verde R, De Masi C, Bianchi SA, Cicchini J, Perroud E, Mehmeti S, Dagand E, Schrinner S, Nurnberger A, SchmidtK, Metz K, Zwingmann C, Brieske N, Springer C, Hernandez AM, Herzog S, Grabbe F, Sieverding C, Fischer B, Schrader K, Brockmeyer M, Dettmer S, Helbig C, Alunni V, Battaini MA, Mura C, Henrichsen CN, Garcia-Lopez R, Echevarria D, Puelles E, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
1*	J:171409 GUDMAP Consortium, GUDMAP: the GenitoUrinary Development Molecular Anatomy Project. www.gudmap.org. 2004;
4*	J:347774 Kolonay DW, Sattler KM, Strawser C, Rafael-Fortney J, Mihaylova MM, Miller KE, Lepper C, Baskin KK, Temporal regulation of the Mediator complex during muscle proliferation, differentiation, regeneration, aging, and disease. Front Cell Dev Biol. 2024;12:1331563
1*	J:309620 Tan C, Zhu S, Chen Z, Liu C, Li YE, Zhu M, Zhang Z, Zhang Z, Zhang L, Gu Y, Liang Z, Boyer TG, Ouyang K, Evans SM, Fang X, Mediator complex proximal Tail subunit MED30 is critical for Mediator core stability and cardiomyocyte transcriptional network. PLoS Genet. 2021 Sep;17(9):e1009785
4	J:334076 Yang Y, Li C, Chen Z, Zhang Y, Tian Q, Sun M, Zhang S, Yu M, Wang G, An intellectual disability-related MED23 mutation dysregulates gene expression by altering chromatin conformation and enhancer activities. Nucleic Acids Res. 2023 Mar 21;51(5):2137-2150
2	J:324181 Yang Y, Xiao Q, Yin J, Li C, Yu D, He Y, Yang Z, Wang G, Med23 supports angiogenesis and maintains vascular integrity through negative regulation of angiopoietin2 expression. Commun Biol. 2022 Apr 19;5(1):374