Gene Expression Literature Summary

• Symbol: Draxin
• Name: dorsal inhibitory axon guidance protein
• ID: MGI:1917683

18 matching records from 18 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.

Age	E9.5	E10.5	E11.5	E12.5	E13	E13.5	E14.5	E15	E15.5	E16.5	E17	E17.5	E18.5	E	P
Immunohistochemistry (section)		1	1	1			1		1			3			1
In situ RNA (section)	1	2	2	1		3	4		3	2		2	3		3
In situ RNA (whole mount)	1
In situ reporter (knock in)	1	2	1		1	1	2		2			4	1	1	4
Western blot									1
RT-PCR						1		1			1		1		2
cDNA clones									1					1

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Draxin  dorsal inhibitory axon guidance protein   (Synonyms: 2610109H07Rik, Neucrin)
Results	Reference
5*	J:163934 Ahmed G, Shinmyo Y, Naser IB, Hossain M, Song X, Tanaka H, Olfactory bulb axonal outgrowth is inhibited by draxin. Biochem Biophys Res Commun. 2010 Aug 6;398(4):730-4
1*	J:313619 Bedogni F, Hevner RF, Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development. Front Mol Neurosci. 2021;14:686034
1	J:235552 Chinn GA, Hirokawa KE, Chuang TM, Urbina C, Patel F, Fong J, Funatsu N, Monuki ES, Agenesis of the Corpus Callosum Due to Defective Glial Wedge Formation in Lhx2 Mutant Mice. Cereb Cortex. 2015 Sep;25(9):2707-18
1	J:182705 Choe Y, Siegenthaler JA, Pleasure SJ, A cascade of morphogenic signaling initiated by the meninges controls corpus callosum formation. Neuron. 2012 Feb 23;73(4):698-712
1*	J:153498 Diez-Roux G, Banfi S, Sultan M, Geffers L, Anand S, Rozado D, Magen A, Canidio E, Pagani M, Peluso I, Lin-Marq N, Koch M, Bilio M, Cantiello I, Verde R, De Masi C, Bianchi SA, Cicchini J, Perroud E, Mehmeti S, Dagand E, Schrinner S, Nurnberger A, SchmidtK, Metz K, Zwingmann C, Brieske N, Springer C, Hernandez AM, Herzog S, Grabbe F, Sieverding C, Fischer B, Schrader K, Brockmeyer M, Dettmer S, Helbig C, Alunni V, Battaini MA, Mura C, Henrichsen CN, Garcia-Lopez R, Echevarria D, Puelles E, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
5	J:197462 Dillman AA, Hauser DN, Gibbs JR, Nalls MA, McCoy MK, Rudenko IN, Galter D, Cookson MR, mRNA expression, splicing and editing in the embryonic and adult mouse cerebral cortex. Nat Neurosci. 2013 Apr;16(4):499-506
3	J:193105 Hossain M, Ahmed G, Naser IB, Shinmyo Y, Ito A, Riyadh MA, Felemban A, Song X, Ohta K, Tanaka H, The combinatorial guidance activities of draxin and Tsukushi are essential for forebrain commissure formation. Dev Biol. 2013 Feb 1;374(1):58-70
12	J:144923 Islam SM, Shinmyo Y, Okafuji T, Su Y, Naser IB, Ahmed G, Zhang S, Chen S, Ohta K, Kiyonari H, Abe T, Tanaka S, Nishinakamura R, Terashima T, Kitamura T, Tanaka H, Draxin, a repulsive guidance protein for spinal cord and forebrain commissures. Science. 2009 Jan 16;323(5912):388-93
1	J:217604 Lavado A, Ware M, Pare J, Cao X, The tumor suppressor Nf2 regulates corpus callosum development by inhibiting the transcriptional coactivator Yap. Development. 2014 Nov;141(21):4182-93
6*	J:154861 Miyake A, Takahashi Y, Miwa H, Shimada A, Konishi M, Itoh N, Neucrin is a novel neural-specific secreted antagonist to canonical Wnt signaling. Biochem Biophys Res Commun. 2009 Dec 18;390(3):1051-5
8	J:314104 Morcom L, Edwards TJ, Rider E, Jones-Davis D, Lim JW, Chen KS, Dean RJ, Bunt J, Ye Y, Gobius I, Suarez R, Mandelstam S, Sherr EH, Richards LJ, DRAXIN regulates interhemispheric fissure remodelling to influence the extent of corpus callosum formation. Elife. 2021 May 4;10:e61618
2*	J:222006 Riyadh MA, Shinmyo Y, Ohta K, Tanaka H, Inhibitory effects of draxin on axonal outgrowth and migration of precerebellar neurons. Biochem Biophys Res Commun. 2014 Jun 20;449(1):169-74
6	J:228291 Shinmyo Y, Asrafuzzaman Riyadh M, Ahmed G, Bin Naser I, Hossain M, Takebayashi H, Kawasaki H, Ohta K, Tanaka H, Draxin from neocortical neurons controls the guidance of thalamocortical projections into the neocortex. Nat Commun. 2015;6:10232
1	J:278511 Soldatov R, Kaucka M, Kastriti ME, Petersen J, Chontorotzea T, Englmaier L, Akkuratova N, Yang Y, Haring M, Dyachuk V, Bock C, Farlik M, Piacentino ML, Boismoreau F, Hilscher MM, Yokota C, Qian X, Nilsson M, Bronner ME, Croci L, Hsiao WY, Guertin DA, Brunet JF, Consalez GG, Ernfors P, Fried K, Kharchenko PV, Adameyko I, Spatiotemporal structure of cell fate decisions in murine neural crest. Science. 2019 Jun 7;364(6444)
1	J:286533 Tenney AP, Livet J, Belton T, Prochazkova M, Pearson EM, Whitman MC, Kulkarni AB, Engle EC, Henderson CE, Etv1 Controls the Establishment of Non-overlapping Motor Innervation of Neighboring Facial Muscles during Development. Cell Rep. 2019 Oct 8;29(2):437-452.e4
5*	J:215487 Thompson CL, Ng L, Menon V, Martinez S, Lee CK, Glattfelder K, Sunkin SM, Henry A, Lau C, Dang C, Garcia-Lopez R, Martinez-Ferre A, Pombero A, Rubenstein JL, Wakeman WB, Hohmann J, Dee N, Sodt AJ, Young R, Smith K, Nguyen TN, Kidney J, Kuan L, Jeromin A,Kaykas A, Miller J, Page D, Orta G, Bernard A, Riley Z, Smith S, Wohnoutka P, Hawrylycz MJ, Puelles L, Jones AR, A high-resolution spatiotemporal atlas of gene expression of the developing mouse brain. Neuron. 2014 Jul 16;83(2):309-23
3*	J:239339 Zhang S, Su Y, Gao J, Zhang C, Tanaka H, A potential inhibitory function of draxin in regulating mouse trunk neural crest migration. In Vitro Cell Dev Biol Anim. 2017 Jan;53(1):43-53
3*	J:157200 Zhang S, Su Y, Shinmyo Y, Islam SM, Naser IB, Ahmed G, Tamamaki N, Tanaka H, Draxin, a repulsive axon guidance protein, is involved in hippocampal development. Neurosci Res. 2010 Jan;66(1):53-61