Gene Expression Literature Summary

• Symbol: Pak4
• Name: p21 (RAC1) activated kinase 4
• ID: MGI:1917834

8 matching records from 8 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.

Age	E7	E9.5	E10	E11	E14.5	E15	E17	E17.5	E18.5	E	P
In situ RNA (section)					1
Northern blot	1			1		1	1				1
Western blot		1	1						1	1	6
RT-PCR								1

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Pak4  p21 (RAC1) activated kinase 4   (Synonyms: 5730488L07Rik, mKIAA1142)
Results	Reference
2*	J:357470 Hu B, Moiseev D, Schena I, Faezov B, Dunbrack R, Chernoff J, Li J, PAK2 is necessary for myelination in the peripheral nervous system. Brain. 2024 May 3;147(5):1809-1821
1*	J:85956 Li X, Minden A, Targeted disruption of the gene for the PAK5 kinase in mice. Mol Cell Biol. 2003 Oct;23(20):7134-42
3	J:186592 Nekrasova T, Minden A, Role for p21-activated kinase PAK4 in development of the mammalian heart. Transgenic Res. 2012 Aug;21(4):797-811
6	J:85954 Qu J, Li X, Novitch BG, Zheng Y, Kohn M, Xie JM, Kozinn S, Bronson R, Beg AA, Minden A, PAK4 kinase is essential for embryonic viability and for proper neuronal development. Mol Cell Biol. 2003 Oct;23(20):7122-33
1	J:229358 Teo ZL, McQueen-Miscamble L, Turner K, Martinez G, Madakashira B, Dedhar S, Robinson ML, de Iongh RU, Integrin linked kinase (ILK) is required for lens epithelial cell survival, proliferation and differentiation. Exp Eye Res. 2014 Apr;121:130-42
2*	J:152821 Tian Y, Lei L, Cammarano M, Nekrasova T, Minden A, Essential role for the Pak4 protein kinase in extraembryonic tissue development and vessel formation. Mech Dev. 2009 Aug-Sep;126(8-9):710-20
1	J:173842 Tian Y, Lei L, Minden A, A key role for Pak4 in proliferation and differentiation of neural progenitor cells. Dev Biol. 2011 May 15;353(2):206-16
1*	J:122989 Visel A, Thaller C, Eichele G, GenePaint.org: an atlas of gene expression patterns in the mouse embryo. Nucleic Acids Res. 2004 Jan 1;32(Database issue):D552-6