Gene Expression Literature Summary

• Symbol: Atoh8
• Name: atonal bHLH transcription factor 8
• ID: MGI:1918343

19 matching records from 19 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.

Age	E3.5	E8.5	E9.5	E10.5	E11.5	E12.5	E13.5	E14	E14.5	E15	E15.5	E16	E16.5	E17	E17.5	E18	E18.5	E	P
Immunohistochemistry (section)						1			1							1
In situ RNA (section)				2	1	2	1	1	3		1	1	1		3	1	1		7
Immunohistochemistry (whole mount)	1
In situ RNA (whole mount)		1		2	1	2					2
In situ reporter (knock in)		1	1	2		4			3		1		2		2		1		1
Northern blot		1		1		1		1		1	1	1		1		1	1		2
RT-PCR		1		2		1	2	1	2		2		1		1		1	1	5
cDNA clones											1

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Atoh8  atonal bHLH transcription factor 8   (Synonyms: 4933425C05Rik, bHLHa21, Math6, okadin)
Results	Reference
7	J:278550 Boing M, Brand-Saberi B, Napirei M, Murine transcription factor Math6 is a regulator of placenta development. Sci Rep. 2018 Oct 9;8(1):14997
1	J:248949 Ejarque M, Mir-Coll J, Gomis R, German MS, Lynn FC, Gasa R, Generation of a Conditional Allele of the Transcription Factor Atonal Homolog 8 (Atoh8). PLoS One. 2016;11(1):e0146273
1	J:309350 Estrada SM, Thagard AS, Dehart MJ, Damicis JR, Dornisch EM, Ippolito DL, Burd I, Napolitano PG, Ieronimakis N, The orphan nuclear receptor Nr4a1 mediates perinatal neuroinflammation in a murine model of preterm labor. Cell Death Dis. 2020 Jan 6;11(1):11
4	J:212346 Fang F, Wasserman SM, Torres-Vazquez J, Weinstein B, Cao F, Li Z, Wilson KD, Yue W, Wu JC, Xie X, Pei X, The role of Hath6, a newly identified shear-stress-responsive transcription factor, in endothelial cell differentiation and function. J Cell Sci. 2014 Apr 1;127(Pt 7):1428-40
3*	J:91257 Gray PA, Fu H, Luo P, Zhao Q, Yu J, Ferrari A, Tenzen T, Yuk DI, Tsung EF, Cai Z, Alberta JA, Cheng LP, Liu Y, Stenman JM, Valerius MT, Billings N, Kim HA, Greenberg ME, McMahon AP, Rowitch DH, Stiles CD, Ma Q, Mouse Brain Organization Revealed Through Direct Genome-Scale TF Expression Analysis. Science. 2004 Dec 24;306(5705):2255-2257
3*	J:171409 GUDMAP Consortium, GUDMAP: the GenitoUrinary Development Molecular Anatomy Project. www.gudmap.org. 2004;
12	J:87008 Inoue C, Bae SK, Takatsuka K, Inoue T, Bessho Y, Kageyama R, Math6, a bHLH gene expressed in the developing nervous system, regulates neuronal versus glial differentiation. Genes Cells. 2001 Nov;6(11):977-86
1	J:160796 Lee DH, Zhou LJ, Zhou Z, Xie JX, Jung JU, Liu Y, Xi CX, Mei L, Xiong WC, Neogenin inhibits HJV secretion and regulates BMP-induced hepcidin expression and iron homeostasis. Blood. 2010 Apr 15;115(15):3136-45
13	J:137207 Lynn FC, Sanchez L, Gomis R, German MS, Gasa R, Identification of the bHLH factor Math6 as a novel component of the embryonic pancreas transcriptional network. PLoS One. 2008;3(6):e2430
1	J:185583 Metzakopian E, Lin W, Salmon-Divon M, Dvinge H, Andersson E, Ericson J, Perlmann T, Whitsett JA, Bertone P, Ang SL, Genome-wide characterization of Foxa2 targets reveals upregulation of floor plate genes and repression of ventrolateral genes in midbrain dopaminergic progenitors. Development. 2012 Jul;139(14):2625-34
2	J:293202 Morikawa M, Mitani Y, Holmborn K, Kato T, Koinuma D, Maruyama J, Vasilaki E, Sawada H, Kobayashi M, Ozawa T, Morishita Y, Bessho Y, Maeda S, Ledin J, Aburatani H, Kageyama R, Maruyama K, Heldin CH, Miyazono K, The ALK-1/SMAD/ATOH8 axis attenuates hypoxic responses and protects against the development of pulmonary arterial hypertension. Sci Signal. 2019 Nov 12;12(607)
1	J:328038 Niu F, Che P, Yang Z, Zhang J, Yang L, Zhuang M, Ou X, Ji SJ, m(6)A regulation of cortical and retinal neurogenesis is mediated by the redundant m(6)A readers YTHDFs. iScience. 2022 Sep 16;25(9):104908
5*	J:203454 Rawnsley DR, Xiao J, Lee JS, Liu X, Mericko-Ishizuka P, Kumar V, He J, Basu A, Lu M, Lynn FC, Pack M, Gasa R, Kahn ML, The transcription factor Atonal homolog 8 regulates Gata4 and Friend of Gata-2 during vertebrate development. J Biol Chem. 2013 Aug 23;288(34):24429-40
13*	J:113418 Ross MD, Martinka S, Mukherjee A, Sedor JR, Vinson C, Bruggeman LA, Math6 expression during kidney development and altered expression in a mouse model of glomerulosclerosis. Dev Dyn. 2006 Nov;235(11):3102-9
3	J:279005 Schroeder N, Wuelling M, Hoffmann D, Brand-Saberi B, Vortkamp A, Atoh8 acts as a regulator of chondrocyte proliferation and differentiation in endochondral bones. PLoS One. 2019;14(8):e0218230
1*	J:198239 Tamura M, Hosoya M, Fujita M, Iida T, Amano T, Maeno A, Kataoka T, Otsuka T, Tanaka S, Tomizawa S, Shiroishi T, Overdosage of Hand2 causes limb and heart defects in the human chromosomal disorder partial trisomy distal 4q. Hum Mol Genet. 2013 Jun 15;22(12):2471-81
7	J:308784 Tang Q, Xie MY, Zhang YL, Xue RY, Zhu XH, Yang H, Targeted deletion of Atoh8 results in severe hearing loss in mice. Genesis. 2021 Aug 17;:e23442
9*	J:318603 Wang B, Balakrishnan-Renuka A, Napirei M, Theiss C, Brand-Saberi B, Spatiotemporal expression of Math6 during mouse embryonic development. Histochem Cell Biol. 2015 Jun;143(6):575-82
1*	J:190636 Wiese CB, Ireland S, Fleming NL, Yu J, Valerius MT, Georgas K, Chiu HS, Brennan J, Armstrong J, Little MH, McMahon AP, Southard-Smith EM, A genome-wide screen to identify transcription factors expressed in pelvic ganglia of the lower urinary tract. Front Neurosci. 2012;6:130