Symbol Name ID |
Myh14
myosin, heavy polypeptide 14 MGI:1919210 |
Age | E0.5 | E1.5 | E2.5 | E3.5 | E7.5 | E9.5 | E10.5 | E11.5 | E12.5 | E13.5 | E14.5 | E15 | E15.5 | E16 | E16.5 | E18 | E18.5 | E | P |
Immunohistochemistry (section) | 1 | 1 | 1 | 2 | 3 | 1 | 1 | 1 | 4 | 1 | 1 | 4 | |||||||
In situ RNA (section) | 2 | 1 | 1 | ||||||||||||||||
Immunohistochemistry (whole mount) | 1 | 1 | |||||||||||||||||
In situ RNA (whole mount) | 1 | 1 | |||||||||||||||||
Western blot | 2 | 1 | 5 | ||||||||||||||||
RT-PCR | 1 | 1 | 1 | 1 | 1 | 2 | 1 | 1 | 1 | 2 | 2 | 4 |
Myh14 myosin, heavy polypeptide 14 (Synonyms: 2400004E04Rik, NMHC II-C) | |
Results | Reference |
1* | J:153498 Diez-Roux G, Banfi S, Sultan M, Geffers L, Anand S, Rozado D, Magen A, Canidio E, Pagani M, Peluso I, Lin-Marq N, Koch M, Bilio M, Cantiello I, Verde R, De Masi C, Bianchi SA, Cicchini J, Perroud E, Mehmeti S, Dagand E, Schrinner S, Nurnberger A, SchmidtK, Metz K, Zwingmann C, Brieske N, Springer C, Hernandez AM, Herzog S, Grabbe F, Sieverding C, Fischer B, Schrader K, Brockmeyer M, Dettmer S, Helbig C, Alunni V, Battaini MA, Mura C, Henrichsen CN, Garcia-Lopez R, Echevarria D, Puelles E, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582 |
1 | J:273293 Du TT, Dewey JB, Wagner EL, Cui R, Heo J, Park JJ, Francis SP, Perez-Reyes E, Guillot SJ, Sherman NE, Xu W, Oghalai JS, Kachar B, Shin JB, LMO7 deficiency reveals the significance of the cuticular plate for hearing function. Nat Commun. 2019 Mar 8;10(1):1117 |
4 | J:90427 Golomb E, Ma X, Jana SS, Preston YA, Kawamoto S, Shoham NG, Goldin E, Conti MA, Sellers JR, Adelstein RS, Identification and characterization of nonmuscle myosin II-C, a new member of the myosin II family. J Biol Chem. 2004 Jan 23;279(4):2800-8 |
1 | J:349163 Huycke TR, Hakkinen TJ, Miyazaki H, Srivastava V, Barruet E, McGinnis CS, Kalantari A, Cornwall-Scoones J, Vaka D, Zhu Q, Jo H, Oria R, Weaver VM, DeGrado WF, Thomson M, Garikipati K, Boffelli D, Klein OD, Gartner ZJ, Patterning and folding of intestinal villi by active mesenchymal dewetting. Cell. 2024 Jun 6;187(12):3072-3089.e20 |
4* | J:149772 Jana SS, Kim KY, Mao J, Kawamoto S, Sellers JR, Adelstein RS, An alternatively spliced isoform of non-muscle myosin II-C is not regulated by myosin light chain phosphorylation. J Biol Chem. 2009 Apr 24;284(17):11563-71 |
1 | J:342314 Jun S, Angueira AR, Fein EC, Tan JME, Weller AH, Cheng L, Batmanov K, Ishibashi J, Sakers AP, Stine RR, Seale P, Control of murine brown adipocyte development by GATA6. Dev Cell. 2023 Nov 6;58(21):2195-2205.e5 |
1 | J:222409 Kim S, Lewis AE, Singh V, Ma X, Adelstein R, Bush JO, Convergence and extrusion are required for normal fusion of the mammalian secondary palate. PLoS Biol. 2015 Apr;13(4):e1002122 |
2 | J:199510 Lee J, Andreeva A, Sipe CW, Liu L, Cheng A, Lu X, PTK7 regulates myosin II activity to orient planar polarity in the mammalian auditory epithelium. Curr Biol. 2012 Jun 5;22(11):956-66 |
1 | J:264111 Liu CF, Angelozzi M, Haseeb A, Lefebvre V, SOX9 is dispensable for the initiation of epigenetic remodeling and the activation of marker genes at the onset of chondrogenesis. Development. 2018 Jul 18;145(14):dev164459 |
2 | J:142122 Lu W, Seeholzer SH, Han M, Arnold AS, Serrano M, Garita B, Philp NJ, Farthing C, Steele P, Chen J, Linask KK, Cellular nonmuscle myosins NMHC-IIA and NMHC-IIB and vertebrate heart looping. Dev Dyn. 2008 Dec;237(12):3577-90 |
2 | J:245570 Ma X, Adelstein RS, A point mutation in Myh10 causes major defects in heart development and body wall closure. Circ Cardiovasc Genet. 2014 Jun;7(3):257-65 |
1 | J:127463 Ma X, Bao J, Adelstein RS, Loss of cell adhesion causes hydrocephalus in nonmuscle myosin II-B-ablated and mutated mice. Mol Biol Cell. 2007 Jun;18(6):2305-12 |
2 | J:92081 Ma X, Kawamoto S, Hara Y, Adelstein RS, A point mutation in the motor domain of nonmuscle myosin II-B impairs migration of distinct groups of neurons. Mol Biol Cell. 2004 Jun;15(6):2568-79 |
5 | J:90712 Marigo V, Nigro A, Pecci A, Montanaro D, Di Stazio M, Balduini CL, Savoia A, Correlation between the clinical phenotype of MYH9-related disease and tissue distribution of class II nonmuscle myosin heavy chains. Genomics. 2004 Jun;83(6):1125-33 |
3 | J:187967 Plosa EJ, Gooding KA, Zent R, Prince LS, Nonmuscle myosin II regulation of lung epithelial morphology. Dev Dyn. 2012 Nov;241(11):1770-81 |
2 | J:244798 Recuenco MC, Ohmori T, Tanigawa S, Taguchi A, Fujimura S, Conti MA, Wei Q, Kiyonari H, Abe T, Adelstein RS, Nishinakamura R, Nonmuscle Myosin II Regulates the Morphogenesis of Metanephric Mesenchyme-Derived Immature Nephrons. J Am Soc Nephrol. 2015 May;26(5):1081-91 |
4* | J:308323 Schliffka MF, Tortorelli AF, Ozguc O, de Plater L, Polzer O, Pelzer D, Maitre JL, Multiscale analysis of single and double maternal-zygotic Myh9 and Myh10 mutants during mouse preimplantation development. Elife. 2021 Apr 19;10:e68536 |
1 | J:218919 Sumigray K, Zhou K, Lechler T, Cell-cell adhesions and cell contractility are upregulated upon desmosome disruption. PLoS One. 2014;9(7):e101824 |
1 | J:163702 Wang A, Ma X, Conti MA, Liu C, Kawamoto S, Adelstein RS, Nonmuscle myosin II isoform and domain specificity during early mouse development. Proc Natl Acad Sci U S A. 2010 Aug 17;107(33):14645-50 |
14 | J:149532 Yamamoto N, Okano T, Ma X, Adelstein RS, Kelley MW, Myosin II regulates extension, growth and patterning in the mammalian cochlear duct. Development. 2009 Jun;136(12):1977-86 |
2 | J:317371 Zhang Y, Liu C, Adelstein RS, Ma X, Replacing nonmuscle myosin 2A with myosin 2C1 permits gastrulation but not placenta vascular development in mice. Mol Biol Cell. 2018 Sep 15;29(19):2326-2335 |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 11/19/2024 MGI 6.24 |
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