Gene Expression Literature Summary

• Symbol: Bmper
• Name: BMP-binding endothelial regulator
• ID: MGI:1920480

36 matching records from 36 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.

Age	E7	E7.5	E8	E8.5	E9	E9.5	E10	E10.5	E11.5	E12	E12.5	E13.5	E14.5	E15.5	E16.5	E17.5	E18.5	E	P
Immunohistochemistry (section)						1		1	1		4	1	3				1	1
In situ RNA (section)			1			1		4	1		7	5	7	2	1		2	1
In situ RNA (whole mount)	1			1	1	2	1	2			3	1		1
In situ reporter (knock in)				1		1		1	2	1	1	1	4	2		1	1	2	2
Northern blot																			2
RT-PCR		1		1		1		2	2		2	1	2			1	3		6
cDNA clones				1															1

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Bmper  BMP-binding endothelial regulator   (Synonyms: 3110056H04Rik, Crim3, crossveinless-2, Cv2, CV-2)
Results	Reference
3*	J:272619 Aydogdu N, Rudat C, Trowe MO, Kaiser M, Ludtke TH, Taketo MM, Christoffels VM, Moon A, Kispert A, TBX2 and TBX3 act downstream of canonical WNT signaling in patterning and differentiation of the mouse ureteric mesenchyme. Development. 2018 Nov 26;145(23):dev171827
2*	J:227274 Bloomquist RF, Parnell NF, Phillips KA, Fowler TE, Yu TY, Sharpe PT, Streelman JT, Coevolutionary patterning of teeth and taste buds. Proc Natl Acad Sci U S A. 2015 Nov 3;112(44):E5954-62
1	J:199298 Cao H, Jheon A, Li X, Sun Z, Wang J, Florez S, Zhang Z, McManus MT, Klein OD, Amendt BA, The Pitx2:miR-200c/141:noggin pathway regulates Bmp signaling and ameloblast differentiation. Development. 2013 Aug;140(16):3348-59
2*	J:112220 Caruana G, Cullen-McEwen L, Nelson AL, Kostoulias X, Woods K, Gardiner B, Davis MJ, Taylor DF, Teasdale RD, Grimmond SM, Little MH, Bertram JF, Spatial gene expression in the T-stage mouse metanephros. Gene Expr Patterns. 2006 Dec;6(8):807-25
10*	J:82196 Coffinier C, Ketpura N, Tran U, Geissert D, De Robertis EM, Mouse Crossveinless-2 is the vertebrate homolog of a Drosophila extracellular regulator of BMP signaling. Mech Dev. 2002 Dec;119 Suppl 1:S179-84
1	J:153556 Colasante G, Sessa A, Crispi S, Calogero R, Mansouri A, Collombat P, Broccoli V, Arx acts as a regional key selector gene in the ventral telencephalon mainly through its transcriptional repression activity. Dev Biol. 2009 Oct 1;334(1):59-71
1	J:161416 Collette NM, Genetos DC, Murugesh D, Harland RM, Loots GG, Genetic evidence that SOST inhibits WNT signaling in the limb. Dev Biol. 2010 Jun 15;342(2):169-79
7	J:206881 Dyer L, Wu Y, Moser M, Patterson C, BMPER-induced BMP signaling promotes coronary artery remodeling. Dev Biol. 2014 Feb 15;386(2):385-94
1	J:192165 Forsman CL, Ng BC, Heinze RK, Kuo C, Sergi C, Gopalakrishnan R, Yee D, Graf D, Schwertfeger KL, Petryk A, BMP-binding protein twisted gastrulation is required in mammary gland epithelium for normal ductal elongation and myoepithelial compartmentalization. Dev Biol. 2013 Jan 1;373(1):95-106
1*	J:317897 Gruzdev A, Nguyen M, Kovarova M, Koller BH, PGE2 through the EP4 receptor controls smooth muscle gene expression patterns in the ductus arteriosus critical for remodeling at birth. Prostaglandins Other Lipid Mediat. 2012 Mar;97(3-4):109-19
1*	J:171409 GUDMAP Consortium, GUDMAP: the GenitoUrinary Development Molecular Anatomy Project. www.gudmap.org. 2004;
11	J:157259 Ikeya M, Fukushima K, Kawada M, Onishi S, Furuta Y, Yonemura S, Kitamura T, Nosaka T, Sasai Y, Cv2, functioning as a pro-BMP factor via twisted gastrulation, is required for early development of nephron precursors. Dev Biol. 2010 Jan 15;337(2):405-14
7	J:115338 Ikeya M, Kawada M, Kiyonari H, Sasai N, Nakao K, Furuta Y, Sasai Y, Essential pro-Bmp roles of crossveinless 2 in mouse organogenesis. Development. 2006 Nov;133(22):4463-73
1*	J:139028 Ikeya M, Nosaka T, Fukushima K, Kawada M, Furuta Y, Kitamura T, Sasai Y, Twisted gastrulation mutation suppresses skeletal defect phenotypes in Crossveinless 2 mutant mice. Mech Dev. 2008 Sep-Oct;125(9-10):832-42
1	J:277787 Ikuta K, Fukuda A, Ogawa S, Masuo K, Goto N, Hiramatsu Y, Tsuda M, Kimura Y, Matsumoto Y, Kimura Y, Maruno T, Kanda K, Nishi K, Takaori K, Uemoto S, Takaishi S, Chiba T, Nishi E, Seno H, Nardilysin inhibits pancreatitis and suppresses pancreatic ductal adenocarcinoma initiation in mice. Gut. 2019 May;68(5):882-892
2	J:254511 Inoue K, Hirose M, Inoue H, Hatanaka Y, Honda A, Hasegawa A, Mochida K, Ogura A, The Rodent-Specific MicroRNA Cluster within the Sfmbt2 Gene Is Imprinted and Essential for Placental Development. Cell Rep. 2017 May 2;19(5):949-956
1	J:139700 Jeong J, Li X, McEvilly RJ, Rosenfeld MG, Lufkin T, Rubenstein JL, Dlx genes pattern mammalian jaw primordium by regulating both lower jaw-specific and upper jaw-specific genetic programs. Development. 2008 Sep;135(17):2905-16
2	J:91215 Kamimura M, Matsumoto K, Koshiba-Takeuchi K, Ogura T, Vertebrate crossveinless 2 is secreted and acts as an extracellular modulator of the BMP signaling cascade. Dev Dyn. 2004 Jul;230(3):434-45
1	J:184521 Koss M, Bolze A, Brendolan A, Saggese M, Capellini TD, Bojilova E, Boisson B, Prall OW, Elliott DA, Solloway M, Lenti E, Hidaka C, Chang CP, Mahlaoui N, Harvey RP, Casanova JL, Selleri L, Congenital Asplenia in Mice and Humans with Mutations in a Pbx/Nkx2-5/p15 Module. Dev Cell. 2012 May 15;22(5):913-26
1	J:239872 Larsen BM, Hrycaj SM, Newman M, Li Y, Wellik DM, Mesenchymal Hox6 function is required for mouse pancreatic endocrine cell differentiation. Development. 2015 Nov 15;142(22):3859-68
1	J:356545 Li X, Madison BB, Zacharias W, Kolterud A, States D, Gumucio DL, Deconvoluting the intestine: molecular evidence for a major role of the mesenchyme in the modulation of signaling cross talk. Physiol Genomics. 2007 May 11;29(3):290-301
1	J:323097 Li-Villarreal N, Wong RLY, Garcia MD, Udan RS, Poche RA, Rasmussen TL, Rhyner AM, Wythe JD, Dickinson ME, FOXO1 represses sprouty 2 and sprouty 4 expression to promote arterial specification and vascular remodeling in the mouse yolk sac. Development. 2022 Apr 1;149(7):dev200131
2*	J:147809 Masuda T, Kai N, Sakuma C, Kobayashi K, Koga H, Yaginuma H, Laser capture microdissection and cDNA array analysis for identification of mouse KIAA/FLJ genes differentially expressed in the embryonic dorsal spinal cord. Brain Res. 2009 Jan 16;1249:61-7
7	J:251966 McGarvey AC, Rybtsov S, Souilhol C, Tamagno S, Rice R, Hills D, Godwin D, Rice D, Tomlinson SR, Medvinsky A, A molecular roadmap of the AGM region reveals BMPER as a novel regulator of HSC maturation. J Exp Med. 2017 Dec 4;214(12):3731-3751
1	J:187360 McKean DM, Niswander L, Defects in GPI biosynthesis perturb Cripto signaling during forebrain development in two new mouse models of holoprosencephaly. Biol Open. 2012;1(9):874-883
5*	J:84799 Moser M, Binder O, Wu Y, Aitsebaomo J, Ren R, Bode C, Bautch VL, Conlon FL, Patterson C, BMPER, a novel endothelial cell precursor-derived protein, antagonizes bone morphogenetic protein signaling and endothelial cell differentiation. Mol Cell Biol. 2003 Aug;23(16):5664-79
1*	J:332131 Perera SN, Williams RM, Lyne R, Stubbs O, Buehler DP, Sauka-Spengler T, Noda M, Micklem G, Southard-Smith EM, Baker CVH, Insights into olfactory ensheathing cell development from a laser-microdissection and transcriptome-profiling approach. Glia. 2020 Dec;68(12):2550-2584
1	J:266826 Sandberg M, Flandin P, Silberberg S, Su-Feher L, Price JD, Hu JS, Kim C, Visel A, Nord AS, Rubenstein JLR, Transcriptional Networks Controlled by NKX2-1 in the Development of Forebrain GABAergic Neurons. Neuron. 2016 Sep 21;91(6):1260-1275
2	J:257520 Sardella C, Winkler C, Quignodon L, Hardman JA, Toffoli B, Giordano Attianese GMP, Hundt JE, Michalik L, Vinson CR, Paus R, Desvergne B, Gilardi F, Delayed Hair Follicle Morphogenesis and Hair Follicle Dystrophy in a Lipoatrophy Mouse Model of Pparg Total Deletion. J Invest Dermatol. 2018 Mar;138(3):500-510
4*	J:157819 Shimogori T, Lee DA, Miranda-Angulo A, Yang Y, Wang H, Jiang L, Yoshida AC, Kataoka A, Mashiko H, Avetisyan M, Qi L, Qian J, Blackshaw S, A genomic atlas of mouse hypothalamic development. Nat Neurosci. 2010;13(6):767-75
2	J:311811 Trowe MO, Airik R, Weiss AC, Farin HF, Foik AB, Bettenhausen E, Schuster-Gossler K, Taketo MM, Kispert A, Canonical Wnt signaling regulates smooth muscle precursor development in the mouse ureter. Development. 2012 Sep;139(17):3099-108
3	J:300975 Weiss AC, Rivera-Reyes R, Englert C, Kispert A, Expansion of the renal capsular stroma, ureteric bud branching defects and cryptorchidism in mice with Wilms tumor 1 gene deletion in the stromal compartment of the developing kidney. J Pathol. 2020 Nov;252(3):290-303
7	J:253665 Willis MS, Dyer LA, Ren R, Lockyer P, Moreno-Miralles I, Schisler JC, Patterson C, BMPER regulates cardiomyocyte size and vessel density in vivo. Cardiovasc Pathol. 2013 May-Jun;22(3):228-40
2	J:182757 Wilson DG, Phamluong K, Lin WY, Barck K, Carano RA, Diehl L, Peterson AS, Martin F, Solloway MJ, Chondroitin sulfate synthase 1 (Chsy1) is required for bone development and digit patterning. Dev Biol. 2012 Mar 15;363(2):413-25
2*	J:165712 Zakin L, Chang EY, Plouhinec JL, De Robertis EM, Crossveinless-2 is required for the relocalization of Chordin protein within the vertebral field in mouse embryos. Dev Biol. 2010 Nov 1;347(1):204-15
6*	J:141243 Zakin L, Metzinger CA, Chang EY, Coffinier C, De Robertis EM, Development of the vertebral morphogenetic field in the mouse: interactions between Crossveinless-2 and Twisted Gastrulation. Dev Biol. 2008 Nov 1;323(1):6-18