Gene Expression Literature Summary

• Symbol: Tubb2b
• Name: tubulin, beta 2B class IIB
• ID: MGI:1920960

15 matching records from 15 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.

Age	E10.5	E11	E12	E12.5	E13	E14	E14.5	E15	E16	E16.5	E17.5	E18.5	P
Immunohistochemistry (section)				1									1
In situ RNA (section)							1			1		1	1
Immunohistochemistry (whole mount)												1	1
RT-PCR	2	1	1	2	1	1	2	1	1	3	1	2	7

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Tubb2b  tubulin, beta 2B class IIB   (Synonyms: 2410129E14Rik, brdp)
Results	Reference
6*	J:64688 Arden SD, Zahn T, Steegers S, Webb S, Bergman B, O'Brien RM, Hutton JC, Molecular cloning of a pancreatic islet-specific glucose-6-phosphatase catalytic subunit-related protein. Diabetes. 1999 Mar;48(3):531-42
1	J:278765 Bittermann E, Abdelhamed Z, Liegel RP, Menke C, Timms A, Beier DR, Stottmann RW, Differential requirements of tubulin genes in mammalian forebrain development. PLoS Genet. 2019 Aug;15(8):e1008243
6*	J:169198 Braun A, Breuss M, Salzer MC, Flint J, Cowan NJ, Keays DA, Tuba8 is expressed at low levels in the developing mouse and human brain. Am J Hum Genet. 2010 May 14;86(5):819-22; author reply 822-3
6*	J:196330 Breuss M, Heng JI, Poirier K, Tian G, Jaglin XH, Qu Z, Braun A, Gstrein T, Ngo L, Haas M, Bahi-Buisson N, Moutard ML, Passemard S, Verloes A, Gressens P, Xie Y, Robson KJ, Rani DS, Thangaraj K, Clausen T, Chelly J, Cowan NJ, Keays DA, Mutations in the beta-tubulin gene TUBB5 cause microcephaly with structural brain abnormalities. Cell Rep. 2012 Dec 27;2(6):1554-62
2*	J:227088 Breuss M, Morandell J, Nimpf S, Gstrein T, Lauwers M, Hochstoeger T, Braun A, Chan K, Sanchez Guajardo ER, Zhang L, Suplata M, Heinze KG, Elsayad K, Keays DA, The Expression of Tubb2b Undergoes a Developmental Transition in Murine Cortical Neurons. J Comp Neurol. 2015 Oct 15;523(15):2161-86
1	J:201321 Copley CO, Duncan JS, Liu C, Cheng H, Deans MR, Postnatal refinement of auditory hair cell planar polarity deficits occurs in the absence of Vangl2. J Neurosci. 2013 Aug 28;33(35):14001-16
1*	J:153498 Diez-Roux G, Banfi S, Sultan M, Geffers L, Anand S, Rozado D, Magen A, Canidio E, Pagani M, Peluso I, Lin-Marq N, Koch M, Bilio M, Cantiello I, Verde R, De Masi C, Bianchi SA, Cicchini J, Perroud E, Mehmeti S, Dagand E, Schrinner S, Nurnberger A, SchmidtK, Metz K, Zwingmann C, Brieske N, Springer C, Hernandez AM, Herzog S, Grabbe F, Sieverding C, Fischer B, Schrader K, Brockmeyer M, Dettmer S, Helbig C, Alunni V, Battaini MA, Mura C, Henrichsen CN, Garcia-Lopez R, Echevarria D, Puelles E, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
1	J:231463 Haque K, Pandey AK, Zheng HW, Riazuddin S, Sha SH, Puligilla C, MEKK4 Signaling Regulates Sensory Cell Development and Function in the Mouse Inner Ear. J Neurosci. 2016 Jan 27;36(4):1347-61
1	J:259186 Heng X, Guo Q, Leung AW, Li JY, Analogous mechanism regulating formation of neocortical basal radial glia and cerebellar Bergmann glia. Elife. 2017 May 10;6:e23253
1*	J:248708 Hoffmeister M, Krieg J, Ehrke A, Seigfried FA, Wischmann L, Dietmann P, Kuhl SJ, Oess S, Developmental neurogenesis in mouse and Xenopus is impaired in the absence of Nosip. Dev Biol. 2017 Sep 1;429(1):200-212
1	J:270401 Latremoliere A, Cheng L, DeLisle M, Wu C, Chew S, Hutchinson EB, Sheridan A, Alexandre C, Latremoliere F, Sheu SH, Golidy S, Omura T, Huebner EA, Fan Y, Whitman MC, Nguyen E, Hermawan C, Pierpaoli C, Tischfield MA, Woolf CJ, Engle EC, Neuronal-Specific TUBB3 Is Not Required for Normal Neuronal Function but Is Essential for Timely Axon Regeneration. Cell Rep. 2018 Aug 14;24(7):1865-1879.e9
1	J:195272 Sipe CW, Liu L, Lee J, Grimsley-Myers C, Lu X, Lis1 mediates planar polarity of auditory hair cells through regulation of microtubule organization. Development. 2013 Apr;140(8):1785-95
1	J:201099 Stottmann RW, Donlin M, Hafner A, Bernard A, Sinclair DA, Beier DR, A mutation in Tubb2b, a human polymicrogyria gene, leads to lethality and abnormal cortical development in the mouse. Hum Mol Genet. 2013 Oct 15;22(20):4053-63
2	J:295090 Stoupa A, Adam F, Kariyawasam D, Strassel C, Gawade S, Szinnai G, Kauskot A, Lasne D, Janke C, Natarajan K, Schmitt A, Bole-Feysot C, Nitschke P, Leger J, Jabot-Hanin F, Tores F, Michel A, Munnich A, Besmond C, Scharfmann R, Lanza F, Borgel D, Polak M, Carre A, TUBB1 mutations cause thyroid dysgenesis associated with abnormal platelet physiology. EMBO Mol Med. 2018 Dec;10(12)
2*	J:130714 Tachikawa K, Sasaki S, Maeda T, Nakajima K, Identification of molecules preferentially expressed beneath the marginal zone in the developing cerebral cortex. Neurosci Res. 2008 Feb;60(2):135-46