Gene Expression Literature Summary

• Symbol: Manf
• Name: mesencephalic astrocyte-derived neurotrophic factor
• ID: MGI:1922090

9 matching records from 9 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.

Age	E7.5	E9.5	E11.5	E12.5	E13	E13.5	E14	E15	E15.5	E16	E17	E18	E18.5	E19.5	P
Immunohistochemistry (section)		1		1	1	3	1		1	1	1		2		5
In situ RNA (section)			1	1				1	1		1				2
In situ reporter (knock in)	1	1				1									1
Northern blot															1
Western blot														1	3
RT-PCR					1			1				1			6

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Manf  mesencephalic astrocyte-derived neurotrophic factor   (Synonyms: 3230402M22Rik, Armet)
Results	Reference
2	J:273150 Bell PA, Dennis EP, Hartley CL, Jackson RM, Porter A, Boot-Handford RP, Pirog KA, Briggs MD, Mesencephalic astrocyte-derived neurotropic factor is an important factor in chondrocyte ER homeostasis. Cell Stress Chaperones. 2019 Jan;24(1):159-173
7	J:268295 Danilova T, Belevich I, Li H, Palm E, Jokitalo E, Otonkoski T, Lindahl M, MANF Is Required for the Postnatal Expansion and Maintenance of Pancreatic beta-Cell Mass in Mice. Diabetes. 2019 Jan;68(1):66-80
6	J:284756 Danilova T, Galli E, Pakarinen E, Palm E, Lindholm P, Saarma M, Lindahl M, Mesencephalic Astrocyte-Derived Neurotrophic Factor (MANF) Is Highly Expressed in Mouse Tissues With Metabolic Function. Front Endocrinol (Lausanne). 2019;10:765
1*	J:250135 Ding M, Weng C, Fan S, Cao Q, Lu Z, Purkinje Cell Degeneration and Motor Coordination Deficits in a New Mouse Model of Autosomal Recessive Spastic Ataxia of Charlevoix-Saguenay. Front Mol Neurosci. 2017;10:121
2	J:211812 Lindahl M, Danilova T, Palm E, Lindholm P, Voikar V, Hakonen E, Ustinov J, Andressoo JO, Harvey BK, Otonkoski T, Rossi J, Saarma M, MANF is indispensable for the proliferation and survival of pancreatic beta cells. Cell Rep. 2014 Apr 24;7(2):366-75
15*	J:142284 Lindholm P, Peranen J, Andressoo JO, Kalkkinen N, Kokaia Z, Lindvall O, Timmusk T, Saarma M, MANF is widely expressed in mammalian tissues and differently regulated after ischemic and epileptic insults in rodent brain. Mol Cell Neurosci. 2008 Nov;39(3):356-71
3*	J:162220 Magdaleno S, Jensen P, Brumwell CL, Seal A, Lehman K, Asbury A, Cheung T, Cornelius T, Batten DM, Eden C, Norland SM, Rice DS, Dosooye N, Shakya S, Mehta P, Curran T, BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system. PLoS Biol. 2006 Apr;4(4):e86
2	J:287361 Pakarinen E, Danilova T, Voikar V, Chmielarz P, Piepponen P, Airavaara M, Saarma M, Lindahl M, MANF Ablation Causes Prolonged Activation of the UPR without Neurodegeneration in the Mouse Midbrain Dopamine System. eNeuro. 2020 Jan/Feb;7(1):ENEURO.0477-19.2019
4	J:255942 Tseng KY, Danilova T, Domanskyi A, Saarma M, Lindahl M, Airavaara M, MANF Is Essential for Neurite Extension and Neuronal Migration in the Developing Cortex. eNeuro. 2017 Sep-Oct;4(5):ENEURO.0214-17.2017