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Gene Expression Literature Summary
Symbol
Name
ID
Mei4
meiotic double-stranded break formation protein 4
MGI:1922283

5 matching records from 5 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.
Age E15.5 E16 E P
Immunohistochemistry (section) 2
Immunohistochemistry (whole mount) 1 1 1
Northern blot 1
Western blot 1
RT-PCR 1 1 1 1

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available
Mei4  meiotic double-stranded break formation protein 4   (Synonyms: 4930486G11Rik)
Results  Reference
1J:325094 Guan Y, Lin H, Leu NA, Ruthel G, Fuchs SY, Busino L, Luo M, Wang PJ, SCF ubiquitin E3 ligase regulates DNA double-strand breaks in early meiotic recombination. Nucleic Acids Res. 2022 May 20;50(9):5129-5144
1J:230563 Kato Y, Katsuki T, Kokubo H, Masuda A, Saga Y, Dazl is a target RNA suppressed by mammalian NANOS2 in sexually differentiating male germ cells. Nat Commun. 2016;7:11272
6J:161203 Kumar R, Bourbon HM, de Massy B, Functional conservation of Mei4 for meiotic DNA double-strand break formation from yeasts to mice. Genes Dev. 2010 Jun 15;24(12):1266-80
2J:271216 Kumar R, Oliver C, Brun C, Juarez-Martinez AB, Tarabay Y, Kadlec J, de Massy B, Mouse REC114 is essential for meiotic DNA double-strand break formation and forms a complex with MEI4. Life Sci Alliance. 2018 Dec;1(6):e201800259
1*J:229524 Robert T, Nore A, Brun C, Maffre C, Crimi B, Bourbon HM, de Massy B, The TopoVIB-Like protein family is required for meiotic DNA double-strand break formation. Science. 2016 Feb 26;351(6276):943-9

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory