Gene Expression Literature Summary

• Symbol: Rdh10
• Name: retinol dehydrogenase 10 (all-trans)
• ID: MGI:1924238

34 matching records from 34 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.

Age	E6.5	E7.5	E8	E8.5	E9	E9.5	E10	E10.5	E11	E11.5	E12	E12.5	E13	E13.5	E14	E14.5	E15.5	E16.5	E17	E18.5	E	P
Immunohistochemistry (section)																1
In situ RNA (section)		1	1	3	2	5		4		2		2				8	2	2		3
Immunohistochemistry (whole mount)																				1
In situ RNA (whole mount)		1	2	5	2	4		4		1		4		3		2					1
In situ reporter (knock in)						2		2		2		2				1
Western blot					1		1	1	1		1		1	1
RT-PCR	1	1	1			2		1		1		2		1	1	3	1		1	3	1	3
cDNA clones								1

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Rdh10  retinol dehydrogenase 10 (all-trans)   (Synonyms: 3110069K09Rik, 4921506A21Rik, D1Ertd762e, m366Asp)
Results	Reference
5	J:214109 Adams MK, Belyaeva OV, Wu L, Kedishvili NY, The retinaldehyde reductase activity of DHRS3 is reciprocally activated by retinol dehydrogenase 10 to control retinoid homeostasis. J Biol Chem. 2014 May 23;289(21):14868-80
8	J:240765 Arregi I, Climent M, Iliev D, Strasser J, Gouignard N, Johansson JK, Singh T, Mazur M, Semb H, Artner I, Minichiello L, Pera EM, Retinol Dehydrogenase-10 Regulates Pancreas Organogenesis and Endocrine Cell Differentiation via Paracrine Retinoic Acid Signaling. Endocrinology. 2016 Dec;157(12):4615-4631
3*	J:187867 Ashique AM, May SR, Kane MA, Folias AE, Phamluong K, Choe Y, Napoli JL, Peterson AS, Morphological defects in a novel Rdh10 mutant that has reduced retinoic acid biosynthesis and signaling. Genesis. 2012 May;50(5):415-23
1*	J:313619 Bedogni F, Hevner RF, Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development. Front Mol Neurosci. 2021;14:686034
1	J:203823 Billings SE, Pierzchalski K, Butler Tjaden NE, Pang XY, Trainor PA, Kane MA, Moise AR, The retinaldehyde reductase DHRS3 is essential for preventing the formation of excess retinoic acid during embryonic development. FASEB J. 2013 Dec;27(12):4877-89
15*	J:125490 Cammas L, Romand R, Fraulob V, Mura C, Dolle P, Expression of the murine retinol dehydrogenase 10 (Rdh10) gene correlates with many sites of retinoid signalling during embryogenesis and organ differentiation. Dev Dyn. 2007 Oct;236(10):2899-908
3*	J:94934 Challen GA, Martinez G, Davis MJ, Taylor DF, Crowe M, Teasdale RD, Grimmond SM, Little MH, Identifying the molecular phenotype of renal progenitor cells. J Am Soc Nephrol. 2004 Sep;15(9):2344-57
1*	J:153498 Diez-Roux G, Banfi S, Sultan M, Geffers L, Anand S, Rozado D, Magen A, Canidio E, Pagani M, Peluso I, Lin-Marq N, Koch M, Bilio M, Cantiello I, Verde R, De Masi C, Bianchi SA, Cicchini J, Perroud E, Mehmeti S, Dagand E, Schrinner S, Nurnberger A, SchmidtK, Metz K, Zwingmann C, Brieske N, Springer C, Hernandez AM, Herzog S, Grabbe F, Sieverding C, Fischer B, Schrader K, Brockmeyer M, Dettmer S, Helbig C, Alunni V, Battaini MA, Mura C, Henrichsen CN, Garcia-Lopez R, Echevarria D, Puelles E, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
5	J:175783 Farjo KM, Moiseyev G, Nikolaeva O, Sandell LL, Trainor PA, Ma JX, RDH10 is the primary enzyme responsible for the first step of embryonic Vitamin A metabolism and retinoic acid synthesis. Dev Biol. 2011 Sep 15;357(2):347-55
4*	J:329930 Guertin TM, Palaria A, Mager J, Sandell LL, Trainor PA, Tremblay KD, Deciphering the role of retinoic acid in hepatic patterning and induction in the mouse. Dev Biol. 2022 Nov;491:31-42
1	J:239666 Hagglund AC, Jones I, Carlsson L, A novel mouse model of anterior segment dysgenesis (ASD): conditional deletion of Tsc1 disrupts ciliary body and iris development. Dis Model Mech. 2017 Mar 01;10(3):245-257
1	J:358060 Iskusnykh IY, Fattakhov N, Li Y, Bihannic L, Kirchner MK, Steshina EY, Northcott PA, Chizhikov VV, Lmx1a is a master regulator of the cortical hem. Elife. 2023 Sep 19;12
3*	J:257508 Kawamura Y, Katada S, Noguchi H, Yamamoto H, Sanosaka T, Iihara K, Nakashima K, Synergistic induction of astrocytic differentiation by factors secreted from meninges in the mouse developing brain. FEBS Lett. 2017 Nov;591(22):3709-3720
4*	J:241377 Kurosaka H, Wang Q, Sandell L, Yamashiro T, Trainor PA, Rdh10 loss-of-function and perturbed retinoid signaling underlies the etiology of choanal atresia. Hum Mol Genet. 2017 Apr 01;26(7):1268-1279
2*	J:237064 Lenti E, Farinello D, Yokoyama KK, Penkov D, Castagnaro L, Lavorgna G, Wuputra K, Sandell LL, Tjaden NE, Bernassola F, Caridi N, De Antoni A, Wagner M, Kozinc K, Niederreither K, Blasi F, Pasini D, Majdic G, Tonon G, Trainor PA, Brendolan A, Transcription factor TLX1 controls retinoic acid signaling to ensure spleen development. J Clin Invest. 2016 Jul 01;126(7):2452-64
1*	J:221341 Lun MP, Johnson MB, Broadbelt KG, Watanabe M, Kang YJ, Chau KF, Springel MW, Malesz A, Sousa AM, Pletikos M, Adelita T, Calicchio ML, Zhang Y, Holtzman MJ, Lidov HG, Sestan N, Steen H, Monuki ES, Lehtinen MK, Spatially heterogeneous choroid plexus transcriptomes encode positional identity and contribute to regional CSF production. J Neurosci. 2015 Mar 25;35(12):4903-16
2*	J:316714 Mason MK, Hockman D, Curry L, Cunningham TJ, Duester G, Logan M, Jacobs DS, Illing N, Retinoic acid-independent expression of Meis2 during autopod patterning in the developing bat and mouse limb. Evodevo. 2015;6:6
1	J:349775 Matern MS, Durruthy-Durruthy R, Birol O, Darmanis S, Scheibinger M, Groves AK, Heller S, Transcriptional dynamics of delaminating neuroblasts in the mouse otic vesicle. Cell Rep. 2023 Jun 27;42(6):112545
2	J:266575 Metzler MA, Raja S, Elliott KH, Friedl RM, Tran NQH, Brugmann SA, Larsen M, Sandell LL, RDH10-mediated retinol metabolism and RARalpha-mediated retinoic acid signaling are required for submandibular salivary gland initiation. Development. 2018 Aug 2;145(15):dev164822
3	J:247259 Naruse C, Shibata S, Tamura M, Kawaguchi T, Abe K, Sugihara K, Kato T, Nishiuchi T, Wakana S, Ikawa M, Asano M, New insights into the role of Jmjd3 and Utx in axial skeletal formation in mice. FASEB J. 2017 Jun;31(6):2252-2266
1	J:294163 Ono K, Sandell LL, Trainor PA, Wu DK, Retinoic acid synthesis and autoregulation mediate zonal patterning of vestibular organs and inner ear morphogenesis. Development. 2020 Aug 7;147(15):dev192070
1	J:276877 Qu X, Harmelink C, Baldwin HS, Tie2 regulates endocardial sprouting and myocardial trabeculation. JCI Insight. 2019 May 21;5
1	J:343286 Queen R, Crosier M, Eley L, Kerwin J, Turner JE, Yu J, Alqahtani A, Dhanaseelan T, Overman L, Soetjoadi H, Baldock R, Coxhead J, Boczonadi V, Laude A, Cockell SJ, Kane MA, Lisgo S, Henderson DJ, Spatial transcriptomics reveals novel genes during the remodelling of the embryonic human arterial valves. PLoS Genet. 2023 Nov;19(11):e1010777
11*	J:137638 Romand R, Kondo T, Cammas L, Hashino E, Dolle P, Dynamic expression of the retinoic acid-synthesizing enzyme retinol dehydrogenase 10 (rdh10) in the developing mouse brain and sensory organs. J Comp Neurol. 2008 Jun 20;508(6):879-92
5	J:185330 Sandell LL, Lynn ML, Inman KE, McDowell W, Trainor PA, RDH10 oxidation of Vitamin A is a critical control step in synthesis of retinoic acid during mouse embryogenesis. PLoS One. 2012;7(2):e30698
7*	J:121229 Sandell LL, Sanderson BW, Moiseyev G, Johnson T, Mushegian A, Young K, Rey JP, Ma JX, Staehling-Hampton K, Trainor PA, RDH10 is essential for synthesis of embryonic retinoic acid and is required for limb, craniofacial, and organ development. Genes Dev. 2007 May 1;21(9):1113-24
4*	J:100233 Shou S, Scott V, Reed C, Hitzemann R, Stadler HS, Transcriptome analysis of the murine forelimb and hindlimb autopod. Dev Dyn. 2005 Sep;234(1):74-89
1	J:157301 Siegenthaler JA, Ashique AM, Zarbalis K, Patterson KP, Hecht JH, Kane MA, Folias AE, Choe Y, May SR, Kume T, Napoli JL, Peterson AS, Pleasure SJ, Retinoic acid from the meninges regulates cortical neuron generation. Cell. 2009 Oct 30;139(3):597-609
1*	J:196070 Tochitani S, Kondo S, Immunoreactivity for GABA, GAD65, GAD67 and Bestrophin-1 in the meninges and the choroid plexus: implications for non-neuronal sources for GABA in the developing mouse brain. PLoS One. 2013;8(2):e56901
1*	J:122989 Visel A, Thaller C, Eichele G, GenePaint.org: an atlas of gene expression patterns in the mouse embryo. Nucleic Acids Res. 2004 Jan 1;32(Database issue):D552-6
1	J:273816 Wang S, Yu J, Jones JW, Pierzchalski K, Kane MA, Trainor PA, Xavier-Neto J, Moise AR, Retinoic acid signaling promotes the cytoskeletal rearrangement of embryonic epicardial cells. FASEB J. 2018 Jul;32(7):3765-3781
1*	J:227025 Wright DM, Buenger DE, Abashev TM, Lindeman RP, Ding J, Sandell LL, Retinoic acid regulates embryonic development of mammalian submandibular salivary glands. Dev Biol. 2015 Nov 1;407(1):57-67
1	J:283063 Wu L, Belyaeva OV, Adams MK, Klyuyeva AV, Lee SA, Goggans KR, Kesterson RA, Popov KM, Kedishvili NY, Mice lacking the epidermal retinol dehydrogenases SDR16C5 and SDR16C6 display accelerated hair growth and enlarged meibomian glands. J Biol Chem. 2019 Nov 8;294(45):17060-17074
4	J:325311 Wu Y, Kurosaka H, Wang Q, Inubushi T, Nakatsugawa K, Kikuchi M, Ohara H, Tsujimoto T, Natsuyama S, Shida Y, Sandell LL, Trainor PA, Yamashiro T, Retinoic Acid Deficiency Underlies the Etiology of Midfacial Defects. J Dent Res. 2022 Jun;101(6):686-694