Gene Expression Literature Summary

• Symbol: Kcnq4
• Name: potassium voltage-gated channel, subfamily Q, member 4
• ID: MGI:1926803

13 matching records from 13 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.

Age	E9.5	E15	E16	E16.5	E17	E17.5	E18	E18.5	E19	P
Immunohistochemistry (section)										4
In situ RNA (section)										1
Immunohistochemistry (whole mount)				1				2		3
In situ RNA (whole mount)								1
RT-PCR	1	1	1	1	1	1	2	1	1	7

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Kcnq4  potassium voltage-gated channel, subfamily Q, member 4
Results	Reference
6*	J:342400 Beisel KW, Rocha-Sanchez SM, Morris KA, Nie L, Feng F, Kachar B, Yamoah EN, Fritzsch B, Differential expression of KCNQ4 in inner hair cells and sensory neurons is the basis of progressive high-frequency hearing loss. J Neurosci. 2005 Oct 5;25(40):9285-93
1	J:239907 Fulcoli FG, Franzese M, Liu X, Zhang Z, Angelini C, Baldini A, Rebalancing gene haploinsufficiency in vivo by targeting chromatin. Nat Commun. 2016 Jun 03;7:11688
1	J:330325 Garcia-Anoveros J, Clancy JC, Foo CZ, Garcia-Gomez I, Zhou Y, Homma K, Cheatham MA, Duggan A, Tbx2 is a master regulator of inner versus outer hair cell differentiation. Nature. 2022 May;605(7909):298-303
2*	J:119550 Harrell MD, Harbi S, Hoffman JF, Zavadil J, Coetzee WA, Large-scale analysis of ion channel gene expression in the mouse heart during perinatal development. Physiol Genomics. 2007 Feb 12;28(3):273-83
1	J:232973 Hirst CS, Foong JP, Stamp LA, Fegan E, Dent S, Cooper EC, Lomax AE, Anderson CR, Bornstein JC, Young HM, McKeown SJ, Ion channel expression in the developing enteric nervous system. PLoS One. 2015;10(3):e0123436
6*	J:124074 Holt JR, Stauffer EA, Abraham D, Geleoc GS, Dominant-negative inhibition of M-like potassium conductances in hair cells of the mouse inner ear. J Neurosci. 2007 Aug 15;27(33):8940-51
2	J:212089 Iannotti FA, Silvestri C, Mazzarella E, Martella A, Calvigioni D, Piscitelli F, Ambrosino P, Petrosino S, Czifra G, Biro T, Harkany T, Taglialatela M, Di Marzo V, The endocannabinoid 2-AG controls skeletal muscle cell differentiation via CB1 receptor-dependent inhibition of Kv7 channels. Proc Natl Acad Sci U S A. 2014 Jun 17;111(24):E2472-81
1*	J:332214 Kaiser M, Ludtke TH, Deuper L, Rudat C, Christoffels VM, Kispert A, Trowe MO, TBX2 specifies and maintains inner hair and supporting cell fate in the Organ of Corti. Nat Commun. 2022 Dec 9;13(1):7628
1*	J:278471 Nakanishi H, Kurima K, Pan B, Wangemann P, Fitzgerald TS, Geleoc GS, Holt JR, Griffith AJ, Tmc2 expression partially restores auditory function in a mouse model of DFNB7/B11 deafness caused by loss of Tmc1 function. Sci Rep. 2018 Aug 14;8(1):12125
4*	J:118633 Rocha-Sanchez SM, Morris KA, Kachar B, Nichols D, Fritzsch B, Beisel KW, Developmental expression of Kcnq4 in vestibular neurons and neurosensory epithelia. Brain Res. 2007 Mar 30;1139:117-25
1	J:132603 Saul SM, Brzezinski JA 4th, Altschuler RA, Shore SE, Rudolph DD, Kabara LL, Halsey KE, Hufnagel RB, Zhou J, Dolan DF, Glaser T, Math5 expression and function in the central auditory system. Mol Cell Neurosci. 2008 Jan;37(1):153-69
2	J:181639 Wende H, Lechner SG, Cheret C, Bourane S, Kolanczyk ME, Pattyn A, Reuter K, Munier FL, Carroll P, Lewin GR, Birchmeier C, The transcription factor c-Maf controls touch receptor development and function. Science. 2012 Mar 16;335(6074):1373-6
1	J:278320 Wolter S, Mohrle D, Schmidt H, Pfeiffer S, Zelle D, Eckert P, Kramer M, Feil R, Pilz PKD, Knipper M, Ruttiger L, GC-B Deficient Mice With Axon Bifurcation Loss Exhibit Compromised Auditory Processing. Front Neural Circuits. 2018;12:65