Gene Expression Literature Summary

• Symbol: Syne1
• Name: spectrin repeat containing, nuclear envelope 1
• ID: MGI:1927152

12 matching records from 12 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.

Age	E8	E13.5	E14.5	E15.5	E17	E18	E18.5	P
Immunohistochemistry (section)				1			2	5
In situ RNA (section)		1	2
Immunohistochemistry (whole mount)							1	1
In situ RNA (whole mount)	1
Northern blot								1
Western blot							1	1
RT-PCR						1	1	1
cDNA clones					1

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Syne1  spectrin repeat containing, nuclear envelope 1   (Synonyms: A330049M09Rik, C130039F11Rik, enaptin165, MGC:62825, nesprin-1, SYNE-1)
Results	Reference
3	J:65130 Apel ED, Lewis RM, Grady RM, Sanes JR, Syne-1, A dystrophin- and klarsicht-related protein associated with synaptic nuclei at the neuromuscular junction. J Biol Chem. 2000 Oct 13;275(41):31986-95
1*	J:338242 Bellchambers HM, Phatak AR, Nenni MJ, Padua MB, Gao H, Liu Y, Ware SM, Single cell RNA analysis of the left-right organizer transcriptome reveals potential novel heterotaxy genes. Sci Rep. 2023 Jul 1;13(1):10688
1*	J:153498 Diez-Roux G, Banfi S, Sultan M, Geffers L, Anand S, Rozado D, Magen A, Canidio E, Pagani M, Peluso I, Lin-Marq N, Koch M, Bilio M, Cantiello I, Verde R, De Masi C, Bianchi SA, Cicchini J, Perroud E, Mehmeti S, Dagand E, Schrinner S, Nurnberger A, SchmidtK, Metz K, Zwingmann C, Brieske N, Springer C, Hernandez AM, Herzog S, Grabbe F, Sieverding C, Fischer B, Schrader K, Brockmeyer M, Dettmer S, Helbig C, Alunni V, Battaini MA, Mura C, Henrichsen CN, Garcia-Lopez R, Echevarria D, Puelles E, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
1	J:349860 Hashimoto K, Ohira M, Kodama A, Kimoto M, Inoue M, Tone S, Usui Y, Hanashima A, Goto T, Ogura Y, Ujihara Y, Mohri S, Loss of connectin novex-3 leads to heart dysfunction associated with impaired cardiomyocyte proliferation and abnormal nuclear mechanics. Sci Rep. 2024 Jun 14;14(1):13727
3*	J:150047 Lei K, Zhang X, Ding X, Guo X, Chen M, Zhu B, Xu T, Zhuang Y, Xu R, Han M, SUN1 and SUN2 play critical but partially redundant roles in anchoring nuclei in skeletal muscle cells in mice. Proc Natl Acad Sci U S A. 2009 Jun 23;106(25):10207-12
2*	J:190404 Morimoto A, Shibuya H, Zhu X, Kim J, Ishiguro K, Han M, Watanabe Y, A conserved KASH domain protein associates with telomeres, SUN1, and dynactin during mammalian meiosis. J Cell Biol. 2012 Jul 23;198(2):165-72
2	J:339839 Ross JA, Arcos-Villacis N, Battey E, Boogerd C, Orellana CA, Marhuenda E, Swiatlowska P, Hodzic D, Prin F, Mohun T, Catibog N, Tapia O, Gerace L, Iskratsch T, Shah AM, Stroud MJ, Lem2 is essential for cardiac development by maintaining nuclear integrity. Cardiovasc Res. 2023 Sep 5;119(11):2074-2088
1	J:301269 Sankoda N, Tanabe W, Tanaka A, Shibata H, Woltjen K, Chiba T, Haga H, Sakai Y, Mandai M, Yamamoto T, Yamada Y, Uemoto S, Kawaguchi Y, Epithelial expression of Gata4 and Sox2 regulates specification of the squamous-columnar junction via MAPK/ERK signaling in mice. Nat Commun. 2021 Jan 25;12(1):560
2	J:246890 Stroud MJ, Feng W, Zhang J, Veevers J, Fang X, Gerace L, Chen J, Nesprin 1alpha2 is essential for mouse postnatal viability and nuclear positioning in skeletal muscle. J Cell Biol. 2017 Jul 03;216(7):1915-1924
1*	J:122989 Visel A, Thaller C, Eichele G, GenePaint.org: an atlas of gene expression patterns in the mouse embryo. Nucleic Acids Res. 2004 Jan 1;32(Database issue):D552-6
2	J:168852 Yu J, Lei K, Zhou M, Craft CM, Xu G, Xu T, Zhuang Y, Xu R, Han M, KASH protein Syne-2/Nesprin-2 and SUN proteins SUN1/2 mediate nuclear migration during mammalian retinal development. Hum Mol Genet. 2011 Mar 15;20(6):1061-73
2	J:155113 Zhang X, Lei K, Yuan X, Wu X, Zhuang Y, Xu T, Xu R, Han M, SUN1/2 and Syne/Nesprin-1/2 complexes connect centrosome to the nucleus during neurogenesis and neuronal migration in mice. Neuron. 2009 Oct 29;64(2):173-87