Gene Expression Literature Summary

• Symbol: Foxb1
• Name: forkhead box B1
• ID: MGI:1927549

37 matching records from 37 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.

Age	E7	E7.5	E8	E8.5	E9	E9.5	E10	E10.5	E11.5	E12.5	E13	E13.5	E14.5	E15.5	E16.5	E17.5	E18.5	E19.5	E	P
Immunohistochemistry (section)												1
In situ RNA (section)	1	1	2	4	1	3		2	3	7		8	11	5	5		9			7
In situ RNA (whole mount)	2	2	1	4	2	5	1	7	2	3				2			1
In situ reporter (knock in)						1		1	1	1		1	2		1	1	3	1		1
Northern blot								1						1					1
RT-PCR										2	1
cDNA clones				2						1			1						1	3
RNase protection						1		1	1	1			1		1		1			2

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Foxb1  forkhead box B1   (Synonyms: C43, Fkh5, Foxb1a, Foxb1b, Hfh-e5.1, Mf3, TWH)
Results	Reference
9	J:53741 Alvarez-Bolado G, Cecconi F, Wehr R, Gruss P, The fork head transcription factor Fkh5/Mf3 is a developmental marker gene for superior colliculus layers and derivatives of the hindbrain somatic afferent zone. Brain Res Dev Brain Res. 1999 Feb 5;112(2):205-15
6	J:60093 Alvarez-Bolado G, Zhou X, Voss AK, Thomas T, Gruss P, Winged helix transcription factor Foxb1 is essential for access of mammillothalamic axons to the thalamus. Development. 2000 Mar;127(5):1029-38
8*	J:16244 Ang SL, Wierda A, Wong D, Stevens KA, Cascio S, Rossant J, Zaret KS, The formation and maintenance of the definitive endoderm lineage in the mouse: involvement of HNF3/forkhead proteins. Development. 1993 Dec;119(4):1301-15
2*	J:168654 Chung YC, Tsai YJ, Shiu TY, Sun YY, Wang PF, Chen CL, Screening large numbers of expression patterns of transcription factors in late stages of the mouse thymus. Gene Expr Patterns. 2011 Jan-Feb;11(1-2):84-92
3	J:139297 Dasen JS, De Camilli A, Wang B, Tucker PW, Jessell TM, Hox repertoires for motor neuron diversity and connectivity gated by a single accessory factor, FoxP1. Cell. 2008 Jul 25;134(2):304-16
1*	J:153498 Diez-Roux G, Banfi S, Sultan M, Geffers L, Anand S, Rozado D, Magen A, Canidio E, Pagani M, Peluso I, Lin-Marq N, Koch M, Bilio M, Cantiello I, Verde R, De Masi C, Bianchi SA, Cicchini J, Perroud E, Mehmeti S, Dagand E, Schrinner S, Nurnberger A, SchmidtK, Metz K, Zwingmann C, Brieske N, Springer C, Hernandez AM, Herzog S, Grabbe F, Sieverding C, Fischer B, Schrader K, Brockmeyer M, Dettmer S, Helbig C, Alunni V, Battaini MA, Mura C, Henrichsen CN, Garcia-Lopez R, Echevarria D, Puelles E, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
9*	J:40032 Dou C, Ye X, Stewart C, Lai E, Li SC, TWH regulates the development of subsets of spinal cord neurons. Neuron. 1997 Apr;18(4):539-51
3*	J:91257 Gray PA, Fu H, Luo P, Zhao Q, Yu J, Ferrari A, Tenzen T, Yuk DI, Tsung EF, Cai Z, Alberta JA, Cheng LP, Liu Y, Stenman JM, Valerius MT, Billings N, Kim HA, Greenberg ME, McMahon AP, Rowitch DH, Stiles CD, Ma Q, Mouse Brain Organization Revealed Through Direct Genome-Scale TF Expression Analysis. Science. 2004 Dec 24;306(5705):2255-2257
1*	J:171409 GUDMAP Consortium, GUDMAP: the GenitoUrinary Development Molecular Anatomy Project. www.gudmap.org. 2004;
3*	J:166749 Hammock EA, Eagleson KL, Barlow S, Earls LR, Miller DM 3rd, Levitt P, Homologs of genes expressed in Caenorhabditis elegans GABAergic neurons are also found in the developing mouse forebrain. Neural Dev. 2010;5(1):32
5	J:306316 Hou Y, Zhang Q, Liu H, Wu J, Shi Y, Qi Y, Shao M, Yang Z, Lu J, Wu Z, Gong L, He M, Topographical organization of mammillary neurogenesis and efferent projections in the mouse brain. Cell Rep. 2021 Feb 9;34(6):108712
8*	J:14165 Kaestner KH, Lee KH, Schlondorff J, Hiemisch H, Monaghan AP, Schutz G, Six members of the mouse forkhead gene family are developmentally regulated. Proc Natl Acad Sci U S A. 1993 Aug 15;90(16):7628-31
9*	J:32832 Kaestner KH, Schutz G, Monaghan AP, Expression of the winged helix genes fkh-4 and fkh-5 defines domains in the central nervous system. Mech Dev. 1996 Apr;55(2):221-30
1	J:295412 Kim DW, Washington PW, Wang ZQ, Lin SH, Sun C, Ismail BT, Wang H, Jiang L, Blackshaw S, The cellular and molecular landscape of hypothalamic patterning and differentiation from embryonic to late postnatal development. Nat Commun. 2020 Aug 31;11(1):4360
1*	J:252112 Kim JJ, Jiwani T, Erwood S, Loree J, Rosenblum ND, Suppressor of fused controls cerebellar neuronal differentiation in a manner modulated by GLI3 repressor and Fgf15. Dev Dyn. 2018 Jan;247(1):156-169
1*	J:50697 Labosky PA, Kaestner KH, The winged helix transcription factor Hfh2 is expressed in neural crest and spinal cord during mouse development. Mech Dev. 1998 Aug;76(1-2):185-90
13*	J:40034 Labosky PA, Winnier GE, Jetton TL, Hargett L, Ryan AK, Rosenfeld MG, Parlow AF, Hogan BLM, The winged helix gene, Mf3, is required for normal development of the diencephalon and midbrain, postnatal growth and the milk-ejection reflex. Development. 1997 APR;124(7):1263-1274
1	J:308430 Lopez-Gonzalez L, Alonso A, Garcia-Calero E, de Puelles E, Puelles L, Tangential Intrahypothalamic Migration of the Mouse Ventral Premamillary Nucleus and Fgf8 Signaling. Front Cell Dev Biol. 2021;9:676121
2	J:104419 Marion JF, Yang C, Caqueret A, Boucher F, Michaud JL, Sim1 and Sim2 are required for the correct targeting of mammillary body axons. Development. 2005 Dec;132(24):5527-37
1	J:239291 Metzakopian E, Bouhali K, Alvarez-Saavedra M, Whitsett JA, Picketts DJ, Ang SL, Genome-wide characterisation of Foxa1 binding sites reveals several mechanisms for regulating neuronal differentiation in midbrain dopamine cells. Development. 2015 Apr 01;142(7):1315-24
1	J:266266 Newman EA, Wu D, Taketo MM, Zhang J, Blackshaw S, Canonical Wnt signaling regulates patterning, differentiation and nucleogenesis in mouse hypothalamus and prethalamus. Dev Biol. 2018 Oct 15;442(2):236-248
4*	J:209112 Shimizu H, Kubo A, Uchibe K, Hashimoto M, Yokoyama S, Takada S, Mitsuoka K, Asahara H, The AERO system: a 3D-like approach for recording gene expression patterns in the whole mouse embryo. PLoS One. 2013;8(10):e75754
4*	J:157819 Shimogori T, Lee DA, Miranda-Angulo A, Yang Y, Wang H, Jiang L, Yoshida AC, Kataoka A, Mashiko H, Avetisyan M, Qi L, Qian J, Blackshaw S, A genomic atlas of mouse hypothalamic development. Nat Neurosci. 2010;13(6):767-75
1	J:135239 Skidmore JM, Cramer JD, Martin JF, Martin DM, Cre fate mapping reveals lineage specific defects in neuronal migration with loss of Pitx2 function in the developing mouse hypothalamus and subthalamic nucleus. Mol Cell Neurosci. 2008 Apr;37(4):696-707
1	J:294106 Soulez M, Saba-El-Leil MK, Turgeon B, Mathien S, Coulombe P, Klinger S, Rousseau J, Levesque K, Meloche S, Reevaluation of the Role of Extracellular Signal-Regulated Kinase 3 in Perinatal Survival and Postnatal Growth Using New Genetically Engineered Mouse Models. Mol Cell Biol. 2019 Mar 15;39(6)
8	J:172723 Szabo NE, Zhao T, Cankaya M, Stoykova A, Zhou X, Alvarez-Bolado G, Interaction between Axons and Specific Populations of Surrounding Cells Is Indispensable for Collateral Formation in the Mammillary System. PLoS One. 2011;6(5):e20315
5	J:149516 Szabo NE, Zhao T, Cankaya M, Theil T, Zhou X, Alvarez-Bolado G, Role of neuroepithelial Sonic hedgehog in hypothalamic patterning. J Neurosci. 2009 May 27;29(21):6989-7002
1	J:145945 Szabo NE, Zhao T, Zhou X, Alvarez-Bolado G, The role of Sonic hedgehog of neural origin in thalamic differentiation in the mouse. J Neurosci. 2009 Feb 25;29(8):2453-66
5*	J:215487 Thompson CL, Ng L, Menon V, Martinez S, Lee CK, Glattfelder K, Sunkin SM, Henry A, Lau C, Dang C, Garcia-Lopez R, Martinez-Ferre A, Pombero A, Rubenstein JL, Wakeman WB, Hohmann J, Dee N, Sodt AJ, Young R, Smith K, Nguyen TN, Kidney J, Kuan L, Jeromin A,Kaykas A, Miller J, Page D, Orta G, Bernard A, Riley Z, Smith S, Wohnoutka P, Hawrylycz MJ, Puelles L, Jones AR, A high-resolution spatiotemporal atlas of gene expression of the developing mouse brain. Neuron. 2014 Jul 16;83(2):309-23
4*	J:184831 Uchibe K, Shimizu H, Yokoyama S, Kuboki T, Asahara H, Identification of novel transcription-regulating genes expressed during murine molar development. Dev Dyn. 2012 Jul;241(7):1217-26
1*	J:122989 Visel A, Thaller C, Eichele G, GenePaint.org: an atlas of gene expression patterns in the mouse embryo. Nucleic Acids Res. 2004 Jan 1;32(Database issue):D552-6
1	J:139698 Wataya T, Ando S, Muguruma K, Ikeda H, Watanabe K, Eiraku M, Kawada M, Takahashi J, Hashimoto N, Sasai Y, Minimization of exogenous signals in ES cell culture induces rostral hypothalamic differentiation. Proc Natl Acad Sci U S A. 2008 Aug 19;105(33):11796-801
4	J:44764 Wehr R, Mansouri A, de Maeyer T, Gruss P, Fkh5-deficient mice show dysgenesis in the caudal midbrain and hypothalamic mammillary body. Development. 1997 Nov;124(22):4447-56
1	J:105897 Wijchers PJ, Hoekman MF, Burbach JP, Smidt MP, Identification of forkhead transcription factors in cortical and dopaminergic areas of the adult murine brain. Brain Res. 2006 Jan 12;1068(1):23-33
3*	J:156017 Yokoyama S, Ito Y, Ueno-Kudoh H, Shimizu H, Uchibe K, Albini S, Mitsuoka K, Miyaki S, Kiso M, Nagai A, Hikata T, Osada T, Fukuda N, Yamashita S, Harada D, Mezzano V, Kasai M, Puri PL, Hayashizaki Y, Okado H, Hashimoto M, Asahara H, A systems approach reveals that the myogenesis genome network is regulated by the transcriptional repressor RP58. Dev Cell. 2009 Dec;17(6):836-48
4	J:168297 Zhao T, Szabo N, Ma J, Luo L, Zhou X, Alvarez-Bolado G, Genetic mapping of Foxb1-cell lineage shows migration from caudal diencephalon to telencephalon and lateral hypothalamus. Eur J Neurosci. 2008 Nov;28(10):1941-55
4	J:130491 Zhao T, Zhou X, Szabo N, Leitges M, Alvarez-Bolado G, Foxb1-driven Cre expression in somites and the neuroepithelium of diencephalon, brainstem, and spinal cord. Genesis. 2007 Dec;45(12):781-7