Symbol Name ID |
Piwil1
piwi-like RNA-mediated gene silencing 1 MGI:1928897 |
Age | E7 | E7.5 | E8.5 | E9.5 | E10.5 | E11 | E11.5 | E12.5 | E13.5 | E14.5 | E15 | E15.5 | E16.5 | E17 | E18.5 | P |
Immunohistochemistry (section) | 6 | |||||||||||||||
In situ RNA (section) | 2 | |||||||||||||||
In situ RNA (whole mount) | 1 | 1 | ||||||||||||||
Northern blot | 1 | 1 | 1 | 1 | 2 | |||||||||||
Western blot | 7 | |||||||||||||||
RT-PCR | 2 | 2 | 1 | 2 | 1 | 2 | 3 | 2 | 1 | 2 | 2 | 12 | ||||
cDNA clones | 1 |
Piwil1 piwi-like RNA-mediated gene silencing 1 (Synonyms: MIWI) | |
Results | Reference |
1* | J:253477 Bailey AS, Batista PJ, Gold RS, Chen YG, de Rooij DG, Chang HY, Fuller MT, The conserved RNA helicase YTHDC2 regulates the transition from proliferation to differentiation in the germline. Elife. 2017 Oct 31;6:e26116 |
1 | J:112036 Costa Y, Speed RM, Gautier P, Semple CA, Maratou K, Turner JM, Cooke HJ, Mouse MAELSTROM: the link between meiotic silencing of unsynapsed chromatin and microRNA pathway?. Hum Mol Genet. 2006 Aug 1;15(15):2324-34 |
1 | J:342617 Dali O, D'Cruz S, Legoff L, Diba Lahmidi M, Heitz C, Merret PE, Kernanec PY, Pakdel F, Smagulova F, Transgenerational epigenetic effects imposed by neonicotinoid thiacloprid exposure. Life Sci Alliance. 2024 Feb;7(2) |
9* | J:77015 Deng W, Lin H, miwi, a murine homolog of piwi, encodes a cytoplasmic protein essential for spermatogenesis. Dev Cell. 2002 Jun;2(6):819-30 |
1 | J:161124 Frost RJ, Hamra FK, Richardson JA, Qi X, Bassel-Duby R, Olson EN, MOV10L1 is necessary for protection of spermatocytes against retrotransposons by Piwi-interacting RNAs. Proc Natl Acad Sci U S A. 2010 Jun 29;107(26):11847-52 |
1* | J:91257 Gray PA, Fu H, Luo P, Zhao Q, Yu J, Ferrari A, Tenzen T, Yuk DI, Tsung EF, Cai Z, Alberta JA, Cheng LP, Liu Y, Stenman JM, Valerius MT, Billings N, Kim HA, Greenberg ME, McMahon AP, Rowitch DH, Stiles CD, Ma Q, Mouse Brain Organization Revealed Through Direct Genome-Scale TF Expression Analysis. Science. 2004 Dec 24;306(5705):2255-2257 |
1* | J:171409 GUDMAP Consortium, GUDMAP: the GenitoUrinary Development Molecular Anatomy Project. www.gudmap.org. 2004; |
1 | J:292511 Gustafson EA, Seymour KA, Sigrist K, Rooij DGDE, Freiman RN, ZFP628 Is a TAF4b-Interacting Transcription Factor Required for Mouse Spermiogenesis. Mol Cell Biol. 2020 Mar 16;40(7) |
1 | J:306320 Ho UY, Feng CA, Yeap YY, Bain AL, Wei Z, Shohayeb B, Reichelt ME, Homer H, Khanna KK, Bowles J, Ng DCH, WDR62 is required for centriole duplication in spermatogenesis and manchette removal in spermiogenesis. Commun Biol. 2021 May 31;4(1):645 |
2 | J:203322 Hussain S, Tuorto F, Menon S, Blanco S, Cox C, Flores JV, Watt S, Kudo NR, Lyko F, Frye M, The mouse cytosine-5 RNA methyltransferase NSun2 is a component of the chromatoid body and required for testis differentiation. Mol Cell Biol. 2013 Apr;33(8):1561-70 |
1 | J:262823 Kasowitz SD, Ma J, Anderson SJ, Leu NA, Xu Y, Gregory BD, Schultz RM, Wang PJ, Nuclear m6A reader YTHDC1 regulates alternative polyadenylation and splicing during mouse oocyte development. PLoS Genet. 2018 May;14(5):e1007412 |
1* | J:118291 Kress C, Gautier-Courteille C, Osborne HB, Babinet C, Paillard L, Inactivation of CUG-BP1/CELF1 causes growth, viability, and spermatogenesis defects in mice. Mol Cell Biol. 2007 Feb;27(3):1146-57 |
3 | J:87735 Kuramochi-Miyagawa S, Kimura T, Ijiri TW, Isobe T, Asada N, Fujita Y, Ikawa M, Iwai N, Okabe M, Deng W, Lin H, Matsuda Y, Nakano T, Mili, a mammalian member of piwi family gene, is essential for spermatogenesis. Development. 2004 Feb;131(4):839-49 |
14* | J:71909 Kuramochi-Miyagawa S, Kimura T, Yomogida K, Kuroiwa A, Tadokoro Y, Fujita Y, Sato M, Matsuda Y, Nakano T, Two mouse piwi-related genes: miwi and mili. Mech Dev. 2001 Oct;108(1-2):121-33 |
2* | J:103446 McKee AE, Minet E, Stern C, Riahi S, Stiles CD, Silver PA, A genome-wide in situ hybridization map of RNA-binding proteins reveals anatomically restricted expression in the developing mouse brain. BMC Dev Biol. 2005 Jul 20;5:14 |
1* | J:256987 Shi B, Xue J, Zhou J, Kasowitz SD, Zhang Y, Liang G, Guan Y, Shi Q, Liu M, Sha J, Huang X, Wang PJ, MORC2B is essential for meiotic progression and fertility. PLoS Genet. 2018 Jan;14(1):e1007175 |
2* | J:148942 Vasileva A, Tiedau D, Firooznia A, Muller-Reichert T, Jessberger R, Tdrd6 is required for spermiogenesis, chromatoid body architecture, and regulation of miRNA expression. Curr Biol. 2009 Apr 28;19(8):630-9 |
2 | J:221349 Vourekas A, Zheng K, Fu Q, Maragkakis M, Alexiou P, Ma J, Pillai RS, Mourelatos Z, Wang PJ, The RNA helicase MOV10L1 binds piRNA precursors to initiate piRNA processing. Genes Dev. 2015 Mar 15;29(6):617-29 |
1 | J:306880 Xia Q, Cui G, Fan Y, Wang X, Hu G, Wang L, Luo X, Yang L, Cai Q, Xu K, Guo W, Gao M, Li Y, Wu J, Li W, Chen J, Qi H, Peng G, Yao H, RNA helicase DDX5 acts as a critical regulator for survival of neonatal mouse gonocytes. Cell Prolif. 2021 May;54(5):e13000 |
10 | J:170319 Yabuta Y, Ohta H, Abe T, Kurimoto K, Chuma S, Saitou M, TDRD5 is required for retrotransposon silencing, chromatoid body assembly, and spermiogenesis in mice. J Cell Biol. 2011 Mar 7;192(5):781-95 |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 08/02/2024 MGI 6.24 |
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