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Gene Expression Literature Summary
Symbol
Name
ID
Amotl2
angiomotin-like 2
MGI:1929286

11 matching records from 11 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.
Age E4.5 E5 E6 E7 E8 E9 E10 E10.5 E11 E11.5 E12 E12.5 E13 E13.5 E14 E14.5 E15 E16 E16.5 E17 E18 E18.5 E19 E P
Immunohistochemistry (section) 1 1 1 1
In situ RNA (section) 1
Immunohistochemistry (whole mount) 1
Western blot 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1
RT-PCR 1 1 1 3 1 1

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available
Amotl2  angiomotin-like 2   (Synonyms: Lccp, MASCOT, mKIAA0989)
Results  Reference
3J:123910 Aase K, Ernkvist M, Ebarasi L, Jakobsson L, Majumdar A, Yi C, Birot O, Ming Y, Kvanta A, Edholm D, Aspenstrom P, Kissil J, Claesson-Welsh L, Shimono A, Holmgren L, Angiomotin regulates endothelial cell migration during embryonic angiogenesis. Genes Dev. 2007 Aug 15;21(16):2055-68
1*J:153498 Diez-Roux G, Banfi S, Sultan M, Geffers L, Anand S, Rozado D, Magen A, Canidio E, Pagani M, Peluso I, Lin-Marq N, Koch M, Bilio M, Cantiello I, Verde R, De Masi C, Bianchi SA, Cicchini J, Perroud E, Mehmeti S, Dagand E, Schrinner S, Nurnberger A, SchmidtK, Metz K, Zwingmann C, Brieske N, Springer C, Hernandez AM, Herzog S, Grabbe F, Sieverding C, Fischer B, Schrader K, Brockmeyer M, Dettmer S, Helbig C, Alunni V, Battaini MA, Mura C, Henrichsen CN, Garcia-Lopez R, Echevarria D, Puelles E, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
1J:209773 Gewies A, Castineiras-Vilarino M, Ferch U, Jahrling N, Heinrich K, Hoeckendorf U, Przemeck GK, Munding M, Gross O, Schroeder T, Horsch M, Karran EL, Majid A, Antonowicz S, Beckers J, Hrabe de Angelis M, Dodt HU, Peschel C, Forster I, Dyer MJ, Ruland J, Prdm6 is essential for cardiovascular development in vivo. PLoS One. 2013;8(11):e81833
1*J:256562 Hildebrand S, Hultin S, Subramani A, Petropoulos S, Zhang Y, Cao X, Mpindi J, Kalloniemi O, Johansson S, Majumdar A, Lanner F, Holmgren L, The E-cadherin/AmotL2 complex organizes actin filaments required for epithelial hexagonal packing and blastocyst hatching. Sci Rep. 2017 Aug 25;7(1):9540
16*J:226656 Hultin S, Zheng Y, Mojallal M, Vertuani S, Gentili C, Balland M, Milloud R, Belting HG, Affolter M, Helker CS, Adams RH, Herzog W, Uhlen P, Majumdar A, Holmgren L, AmotL2 links VE-cadherin to contractile actin fibres necessary for aortic lumen expansion. Nat Commun. 2014;5:3743
1*J:199301 Lavado A, He Y, Pare J, Neale G, Olson EN, Giovannini M, Cao X, Tumor suppressor Nf2 limits expansion of the neural progenitor pool by inhibiting Yap/Taz transcriptional coactivators. Development. 2013 Aug;140(16):3323-34
2J:244106 Lin C, Yao E, Zhang K, Jiang X, Croll S, Thompson-Peer K, Chuang PT, YAP is essential for mechanical force production and epithelial cell proliferation during lung branching morphogenesis. Elife. 2017 Mar 21;6:e21130
1J:272609 Nantie LB, Young RE, Paltzer WG, Zhang Y, Johnson RL, Verheyden JM, Sun X, Lats1/2 inactivation reveals Hippo function in alveolar type I cell differentiation during lung transition to air breathing. Development. 2018 Nov 9;145(21):dev163105
1J:224392 Poncy A, Antoniou A, Cordi S, Pierreux CE, Jacquemin P, Lemaigre FP, Transcription factors SOX4 and SOX9 cooperatively control development of bile ducts. Dev Biol. 2015 Aug 15;404(2):136-48
1J:243807 Ragni CV, Diguet N, Le Garrec JF, Novotova M, Resende TP, Pop S, Charon N, Guillemot L, Kitasato L, Badouel C, Dufour A, Olivo-Marin JC, Trouve A, McNeill H, Meilhac SM, Amotl1 mediates sequestration of the Hippo effector Yap1 downstream of Fat4 to restrict heart growth. Nat Commun. 2017 Feb 27;8:14582
1*J:240405 Zhao L, Arsenault M, Ng ET, Longmuss E, Chau TC, Hartwig S, Koopman P, SOX4 regulates gonad morphogenesis and promotes male germ cell differentiation in mice. Dev Biol. 2017 Mar 01;423(1):46-56

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
06/12/2024
MGI 6.13
The Jackson Laboratory