Symbol Name ID |
Arhgap35
Rho GTPase activating protein 35 MGI:1929494 |
Age | E8.5 | E9 | E11.5 | E12 | E12.5 | E13 | E13.5 | E14 | E14.5 | E15 | E15.5 | E16 | E16.5 | E17 | E17.5 | E18 | E18.5 | E | P |
Immunohistochemistry (section) | 1 | ||||||||||||||||||
In situ RNA (section) | 1 | 1 | 3 | 1 | 1 | 1 | 1 | ||||||||||||
In situ RNA (whole mount) | 1 | 1 | |||||||||||||||||
Western blot | 2 | 1 | 1 | 1 | 1 | 1 | 3 | 1 | 1 | 2 | 1 | 3 | |||||||
RT-PCR | 1 | 1 | |||||||||||||||||
cDNA clones | 1 |
Arhgap35 Rho GTPase activating protein 35 (Synonyms: 6430596G11Rik, Grlf1, p190A, p190RhoGAP, P190 RhoGAP) | |
Results | Reference |
1* | J:313619 Bedogni F, Hevner RF, Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development. Front Mol Neurosci. 2021;14:686034 |
4 | J:276248 Bonanomi D, Valenza F, Chivatakarn O, Sternfeld MJ, Driscoll SP, Aslanian A, Lettieri K, Gullo M, Badaloni A, Lewcock JW, Hunter T, Pfaff SL, p190RhoGAP Filters Competing Signals to Resolve Axon Guidance Conflicts. Neuron. 2019 May 8;102(3):602-620.e9 |
13* | J:65296 Brouns MR, Matheson SF, Hu K, Delalle I, Caviness VS, Silver J, Bronson RT, Settleman J, The adhesion signaling molecule p190 RhoGAP is required for morphogenetic processes in neural development. Development. 2000 Nov;127(22):4891-903 |
4 | J:68904 Brouns MR, Matheson SF, Settleman J, p190 RhoGAP is the principal Src substrate in brain and regulates axon outgrowth, guidance and fasciculation. Nat Cell Biol. 2001 Apr;3(4):361-7 |
1* | J:217675 Gao Z, Lee P, Stafford JM, von Schimmelmann M, Schaefer A, Reinberg D, An AUTS2-Polycomb complex activates gene expression in the CNS. Nature. 2014 Dec 18;516(7531):349-54 |
2 | J:178482 Heckman-Stoddard BM, Vargo-Gogola T, Herrick MP, Visbal AP, Lewis MT, Settleman J, Rosen JM, P190A RhoGAP is required for mammary gland development. Dev Biol. 2011 Dec 1;360(1):1-10 |
2* | J:90071 Hernandez SE, Settleman J, Koleske AJ, Adhesion-dependent regulation of p190RhoGAP in the developing brain by the Abl-related gene tyrosine kinase. Curr Biol. 2004 Apr 20;14(8):691-6 |
2 | J:338359 Kaur N, Han W, Li Z, Madrigal MP, Shim S, Pochareddy S, Gulden FO, Li M, Xu X, Xing X, Takeo Y, Li Z, Lu K, Imamura Kawasawa Y, Ballester-Lurbe B, Moreno-Bravo JA, Chedotal A, Terrado J, Perez-Roger I, Koleske AJ, Sestan N, Neural Stem Cells Direct Axon Guidance via Their Radial Fiber Scaffold. Neuron. 2020 Sep 23;107(6):1197-1211.e9 |
1 | J:101055 Kuo G, Arnaud L, Kronstad-O'Brien P, Cooper JA, Absence of Fyn and Src causes a reeler-like phenotype. J Neurosci. 2005 Sep 14;25(37):8578-86 |
1 | J:162785 Naoe H, Araki K, Nagano O, Kobayashi Y, Ishizawa J, Chiyoda T, Shimizu T, Yamamura K, Sasaki Y, Saya H, Kuninaka S, The anaphase-promoting complex/cyclosome activator Cdh1 modulates Rho GTPase by targeting p190 RhoGAP for degradation. Mol Cell Biol. 2010 Aug;30(16):3994-4005 |
1 | J:162994 Nemeth T, Futosi K, Hably C, Brouns MR, Jakob SM, Kovacs M, Kertesz Z, Walzog B, Settleman J, Mocsai A, Neutrophil Functions and Autoimmune Arthritis in the Absence of p190RhoGAP: Generation and Analysis of a Novel Null Mutation in Mice. J Immunol. 2010 Sep 1;185(5):3064-75 |
1 | J:232342 Stewart K, Gaitan Y, Shafer ME, Aoudjit L, Hu D, Sharma R, Tremblay M, Ishii H, Marcotte M, Stanga D, Tang YC, Boualia SK, Nguyen AH, Takano T, Lamarche-Vane N, Vidal S, Bouchard M, A Point Mutation in p190A RhoGAP Affects Ciliogenesis and Leads to Glomerulocystic Kidney Defects. PLoS Genet. 2016 Feb;12(2):e1005785 |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
||
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support. |
last database update 11/12/2024 MGI 6.24 |
|
|