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Gene Expression Literature Summary
Symbol
Name
ID
Hic2
hypermethylated in cancer 2
MGI:1929869

6 matching records from 6 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.
Age E7.5 E8 E8.5 E9.5 E10 E10.5 E11.5 E13.5 E14.5 E15.5 E18.5
Immunohistochemistry (section) 1 1 1
In situ RNA (section) 1 1
In situ RNA (whole mount) 1 1
In situ reporter (knock in) 1 1 1 2 1 1 1
RT-PCR 1 1 1

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available
Hic2  hypermethylated in cancer 2   (Synonyms: HRG22, mKIAA1020)
Results  Reference
12*J:225226 Dykes IM, van Bueren KL, Ashmore RJ, Floss T, Wurst W, Szumska D, Bhattacharya S, Scambler PJ, HIC2 is a novel dosage-dependent regulator of cardiac development located within the distal 22q11 deletion syndrome region. Circ Res. 2014 Jun 20;115(1):23-31
1J:257501 Dykes IM, van Bueren KL, Scambler PJ, HIC2 regulates isoform switching during maturation of the cardiovascular system. J Mol Cell Cardiol. 2018 Jan;114:29-37
2*J:91257 Gray PA, Fu H, Luo P, Zhao Q, Yu J, Ferrari A, Tenzen T, Yuk DI, Tsung EF, Cai Z, Alberta JA, Cheng LP, Liu Y, Stenman JM, Valerius MT, Billings N, Kim HA, Greenberg ME, McMahon AP, Rowitch DH, Stiles CD, Ma Q, Mouse Brain Organization Revealed Through Direct Genome-Scale TF Expression Analysis. Science. 2004 Dec 24;306(5705):2255-2257
1*J:171409 GUDMAP Consortium, GUDMAP: the GenitoUrinary Development Molecular Anatomy Project. www.gudmap.org. 2004;
1J:308922 Medeiros de Araujo JA, Barao S, Mateos-White I, Espinosa A, Costa MR, Gil-Sanz C, Muller U, ZBTB20 is crucial for the specification of a subset of callosal projection neurons and astrocytes in the mammalian neocortex. Development. 2021 Aug 15;148(16):dev196642
1*J:122989 Visel A, Thaller C, Eichele G, GenePaint.org: an atlas of gene expression patterns in the mouse embryo. Nucleic Acids Res. 2004 Jan 1;32(Database issue):D552-6

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
12/10/2024
MGI 6.24
The Jackson Laboratory