Gene Expression Literature Summary

• Symbol: Smoc1
• Name: SPARC related modular calcium binding 1
• ID: MGI:1929878

20 matching records from 20 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.

Age	E7.5	E8	E8.5	E9.5	E10	E10.5	E11	E11.5	E12.5	E13.5	E14	E14.5	E15.5	E16.5	E18.5	E	P
Immunohistochemistry (section)	1								1			1		2	1		1
In situ RNA (section)	1					1			1		1	3	1	1	2		3
In situ RNA (whole mount)	1	1	1	2	1	5	2	3	3	2		1	1
In situ reporter (knock in)						1						1				1	2
RT-PCR						3		1	1	1	1	2		1	3	1	1

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Smoc1  SPARC related modular calcium binding 1   (Synonyms: 2600002F22Rik, SPARC-related protein, SRG)
Results	Reference
2	J:226941 Akerberg BN, Sarangam ML, Stankunas K, Endocardial Brg1 disruption illustrates the developmental origins of semilunar valve disease. Dev Biol. 2015 Nov 1;407(1):158-72
1*	J:313619 Bedogni F, Hevner RF, Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development. Front Mol Neurosci. 2021;14:686034
4	J:174459 Boyle MP, Bernard A, Thompson CL, Ng L, Boe A, Mortrud M, Hawrylycz MJ, Jones AR, Hevner RF, Lein ES, Cell-type-specific consequences of Reelin deficiency in the mouse neocortex, hippocampus, and amygdala. J Comp Neurol. 2011 Aug 1;519(11):2061-89
1*	J:279273 Chen G, Yao Y, Xu G, Zhang X, Regional difference in microRNA regulation in the skull vault. Dev Dyn. 2019 Oct;248(10):1009-1019
1*	J:153498 Diez-Roux G, Banfi S, Sultan M, Geffers L, Anand S, Rozado D, Magen A, Canidio E, Pagani M, Peluso I, Lin-Marq N, Koch M, Bilio M, Cantiello I, Verde R, De Masi C, Bianchi SA, Cicchini J, Perroud E, Mehmeti S, Dagand E, Schrinner S, Nurnberger A, SchmidtK, Metz K, Zwingmann C, Brieske N, Springer C, Hernandez AM, Herzog S, Grabbe F, Sieverding C, Fischer B, Schrader K, Brockmeyer M, Dettmer S, Helbig C, Alunni V, Battaini MA, Mura C, Henrichsen CN, Garcia-Lopez R, Echevarria D, Puelles E, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
3*	J:316178 Gamart J, Barozzi I, Laurent F, Reinhardt R, Martins LR, Oberholzer T, Visel A, Zeller R, Zuniga A, SMAD4 target genes are part of a transcriptional network that integrates the response to BMP and SHH signaling during early limb bud patterning. Development. 2021 Dec 1;148(23):dev200182
12	J:144899 Gersdorff N, Muller M, Schall A, Miosge N, Secreted modular calcium-binding protein-1 localization during mouse embryogenesis. Histochem Cell Biol. 2006 Dec;126(6):705-12
1	J:228726 Golonzhka O, Nord A, Tang PL, Lindtner S, Ypsilanti AR, Ferretti E, Visel A, Selleri L, Rubenstein JL, Pbx Regulates Patterning of the Cerebral Cortex in Progenitors and Postmitotic Neurons. Neuron. 2015 Dec 16;88(6):1192-207
1*	J:228563 Koscielny G, Yaikhom G, Iyer V, Meehan TF, Morgan H, Atienza-Herrero J, Blake A, Chen CK, Easty R, Di Fenza A, Fiegel T, Grifiths M, Horne A, Karp NA, Kurbatova N, Mason JC, Matthews P, Oakley DJ, Qazi A, Regnart J, Retha A, Santos LA, Sneddon DJ, Warren J, Westerberg H, Wilson RJ, Melvin DG, Smedley D, Brown SD, Flicek P, Skarnes WC, Mallon AM, Parkinson H, The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data. Nucleic Acids Res. 2014 Jan;42(Database issue):D802-9
1	J:117793 Kudo LC, Karsten SL, Chen J, Levitt P, Geschwind DH, Genetic analysis of anterior-posterior expression gradients in the developing mammalian forebrain. Cereb Cortex. 2007 Sep;17(9):2108-22
3*	J:226028 Lewandowski JP, Du F, Zhang S, Powell MB, Falkenstein KN, Ji H, Vokes SA, Spatiotemporal regulation of GLI target genes in the mammalian limb bud. Dev Biol. 2015 Oct 1;406(1):92-103
1*	J:139122 Manabe R, Tsutsui K, Yamada T, Kimura M, Nakano I, Shimono C, Sanzen N, Furutani Y, Fukuda T, Oguri Y, Shimamoto K, Kiyozumi D, Sato Y, Sado Y, Senoo H, Yamashina S, Fukuda S, Kawai J, Sugiura N, Kimata K, Hayashizaki Y, Sekiguchi K, Transcriptome-based systematic identification of extracellular matrix proteins. Proc Natl Acad Sci U S A. 2008 Sep 2;105(35):12849-54
1*	J:296149 Morkmued S, Clauss F, Schuhbaur B, Fraulob V, Mathieu E, Hemmerle J, Clevers H, Koo BK, Dolle P, Bloch-Zupan A, Niederreither K, Deficiency of the SMOC2 matricellular protein impairs bone healing and produces age-dependent bone loss. Sci Rep. 2020 Sep 9;10(1):14817
8*	J:169180 Okada I, Hamanoue H, Terada K, Tohma T, Megarbane A, Chouery E, Abou-Ghoch J, Jalkh N, Cogulu O, Ozkinay F, Horie K, Takeda J, Furuichi T, Ikegawa S, Nishiyama K, Miyatake S, Nishimura A, Mizuguchi T, Niikawa N, Hirahara F, Kaname T, Yoshiura K, Tsurusaki Y, Doi H, Miyake N, Furukawa T, Matsumoto N, Saitsu H, SMOC1 is essential for ocular and limb development in humans and mice. Am J Hum Genet. 2011 Jan 7;88(1):30-41
12*	J:153731 Pazin DE, Albrecht KH, Developmental expression of Smoc1 and Smoc2 suggests potential roles in fetal gonad and reproductive tract differentiation. Dev Dyn. 2009 Nov;238(11):2877-90
1	J:154739 Quina LA, Wang S, Ng L, Turner EE, Brn3a and Nurr1 mediate a gene regulatory pathway for habenula development. J Neurosci. 2009 Nov 11;29(45):14309-22
6*	J:174198 Rainger J, van Beusekom E, Ramsay JK, McKie L, Al-Gazali L, Pallotta R, Saponari A, Branney P, Fisher M, Morrison H, Bicknell L, Gautier P, Perry P, Sokhi K, Sexton D, Bardakjian TM, Schneider AS, Elcioglu N, Ozkinay F, Koenig R, Megarbane A, Semerci CN,Khan A, Zafar S, Hennekam R, Sousa SB, Ramos L, Garavelli L, Furga AS, Wischmeijer A, Jackson IJ, Gillessen-Kaesbach G, Brunner HG, Wieczorek D, van Bokhoven H, Fitzpatrick DR, Loss of the BMP Antagonist, SMOC-1, Causes Ophthalmo-Acromelic (Waardenburg Anophthalmia) Syndrome in Humans and Mice. PLoS Genet. 2011 Jul;7(7):e1002114
1	J:314589 Takahata Y, Hagino H, Kimura A, Urushizaki M, Kobayashi S, Wakamori K, Fujiwara C, Nakamura E, Yu K, Kiyonari H, Bando K, Murakami T, Komori T, Hata K, Nishimura R, Smoc1 and Smoc2 regulate bone formation as downstream molecules of Runx2. Commun Biol. 2021 Oct 19;4(1):1199
3*	J:141291 Tamplin OJ, Kinzel D, Cox BJ, Bell CE, Rossant J, Lickert H, Microarray analysis of Foxa2 mutant mouse embryos reveals novel gene expression and inductive roles for the gastrula organizer and its derivatives. BMC Genomics. 2008;9(1):511
1	J:276573 Wiegering A, Petzsch P, Kohrer K, Ruther U, Gerhardt C, GLI3 repressor but not GLI3 activator is essential for mouse eye patterning and morphogenesis. Dev Biol. 2019 Jun 15;450(2):141-154