Symbol Name ID |
Myh10
myosin, heavy polypeptide 10, non-muscle MGI:1930780 |
Age | E0.5 | E1 | E1.5 | E2.5 | E3 | E3.5 | E6.5 | E7 | E7.5 | E8 | E8.5 | E9 | E9.5 | E10 | E10.5 | E11 | E11.5 | E12.5 | E13.5 | E14 | E14.5 | E15 | E15.5 | E16 | E16.5 | E17.5 | E18 | E18.5 | E | P |
Immunohistochemistry (section) | 2 | 1 | 1 | 4 | 7 | 3 | 14 | 6 | 1 | 9 | 4 | 4 | 3 | 6 | 1 | 4 | 1 | 8 | 1 | 1 | 3 | 13 | ||||||||
In situ RNA (section) | 1 | 1 | 5 | 1 | 1 | 1 | 2 | |||||||||||||||||||||||
Immunohistochemistry (whole mount) | 2 | 2 | 2 | 1 | 1 | 1 | 1 | 1 | 3 | 3 | 1 | 1 | 1 | |||||||||||||||||
In situ RNA (whole mount) | 1 | 1 | ||||||||||||||||||||||||||||
In situ reporter (knock in) | 2 | |||||||||||||||||||||||||||||
Northern blot | 1 | |||||||||||||||||||||||||||||
Western blot | 2 | 1 | 1 | 1 | 1 | 1 | 3 | 1 | 3 | 1 | 12 | |||||||||||||||||||
RT-PCR | 1 | 1 | 1 | 1 | 1 | 3 | 1 | 1 | 1 | 2 | 1 | 1 | 7 |
Myh10 myosin, heavy polypeptide 10, non-muscle (Synonyms: 5730504C04Rik, 9330167F11Rik, Fltn, Fltn, mKIAA3005, Myhn-2, Myhn2, myosin IIB, Myosin IIB, NMHC-B, NMHC II-B, nonmuscle myosin heavy chain II-B, nonmuscle myosin heavy chain IIB, SMemb) | |
Results | Reference |
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2 | J:220469 Grego-Bessa J, Hildebrand J, Anderson KV, Morphogenesis of the mouse neural plate depends on distinct roles of cofilin 1 in apical and basal epithelial domains. Development. 2015 Apr 1;142(7):1305-14 |
1 | J:239161 Guo C, Balsara ZR, Hill WG, Li X, Stage- and subunit-specific functions of polycomb repressive complex 2 in bladder urothelial formation and regeneration. Development. 2017 Feb 01;144(3):400-408 |
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1 | J:83331 Huang H, Paliouras M, Rambaldi I, Lasko P, Featherstone M, Nonmuscle myosin promotes cytoplasmic localization of PBX. Mol Cell Biol. 2003 May;23(10):3636-45 |
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3 | J:245570 Ma X, Adelstein RS, A point mutation in Myh10 causes major defects in heart development and body wall closure. Circ Cardiovasc Genet. 2014 Jun;7(3):257-65 |
6 | J:127463 Ma X, Bao J, Adelstein RS, Loss of cell adhesion causes hydrocephalus in nonmuscle myosin II-B-ablated and mutated mice. Mol Biol Cell. 2007 Jun;18(6):2305-12 |
3 | J:92081 Ma X, Kawamoto S, Hara Y, Adelstein RS, A point mutation in the motor domain of nonmuscle myosin II-B impairs migration of distinct groups of neurons. Mol Biol Cell. 2004 Jun;15(6):2568-79 |
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1 | J:219576 McGreevy EM, Vijayraghavan D, Davidson LA, Hildebrand JD, Shroom3 functions downstream of planar cell polarity to regulate myosin II distribution and cellular organization during neural tube closure. Biol Open. 2015;4(2):186-96 |
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1 | J:343286 Queen R, Crosier M, Eley L, Kerwin J, Turner JE, Yu J, Alqahtani A, Dhanaseelan T, Overman L, Soetjoadi H, Baldock R, Coxhead J, Boczonadi V, Laude A, Cockell SJ, Kane MA, Lisgo S, Henderson DJ, Spatial transcriptomics reveals novel genes during the remodelling of the embryonic human arterial valves. PLoS Genet. 2023 Nov;19(11):e1010777 |
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5 | J:248868 Ridge LA, Mitchell K, Al-Anbaki A, Shaikh Qureshi WM, Stephen LA, Tenin G, Lu Y, Lupu IE, Clowes C, Robertson A, Barnes E, Wright JA, Keavney B, Ehler E, Lovell SC, Kadler KE, Hentges KE, Non-muscle myosin IIB (Myh10) is required for epicardial function and coronary vessel formation during mammalian development. PLoS Genet. 2017 Oct;13(10):e1007068 |
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1 | J:250140 Wilson NR, Olm-Shipman AJ, Acevedo DS, Palaniyandi K, Hall EG, Kosa E, Stumpff KM, Smith GJ, Pitstick L, Liao EC, Bjork BC, Czirok A, Saadi I, SPECC1L deficiency results in increased adherens junction stability and reduced cranial neural crest cell delamination. Sci Rep. 2016 Jan 20;6:17735 |
1 | J:278242 Xia M, Luo W, Jin H, Yang Z, HAND2-mediated epithelial maintenance and integrity in cardiac outflow tract morphogenesis. Development. 2019 Jul 4;146(13):dev177477 |
3* | J:305110 Xu X, Vogel BE, A secreted protein promotes cleavage furrow maturation during cytokinesis. Curr Biol. 2011 Jan 25;21(2):114-9 |
13 | J:149532 Yamamoto N, Okano T, Ma X, Adelstein RS, Kelley MW, Myosin II regulates extension, growth and patterning in the mammalian cochlear duct. Development. 2009 Jun;136(12):1977-86 |
1 | J:158149 Yen WW, Williams M, Periasamy A, Conaway M, Burdsal C, Keller R, Lu X, Sutherland A, PTK7 is essential for polarized cell motility and convergent extension during mouse gastrulation. Development. 2009 Jun;136(12):2039-48 |
1 | J:168852 Yu J, Lei K, Zhou M, Craft CM, Xu G, Xu T, Zhuang Y, Xu R, Han M, KASH protein Syne-2/Nesprin-2 and SUN proteins SUN1/2 mediate nuclear migration during mammalian retinal development. Hum Mol Genet. 2011 Mar 15;20(6):1061-73 |
1 | J:317371 Zhang Y, Liu C, Adelstein RS, Ma X, Replacing nonmuscle myosin 2A with myosin 2C1 permits gastrulation but not placenta vascular development in mice. Mol Biol Cell. 2018 Sep 15;29(19):2326-2335 |
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last database update 11/12/2024 MGI 6.24 |
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