Symbol Name ID |
Wwox
WW domain-containing oxidoreductase MGI:1931237 |
Age | E8.5 | E9.5 | E10.5 | E11.5 | E12.5 | E14.5 | E16.5 | E17.5 | E18.5 | P |
Immunohistochemistry (section) | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 3 |
In situ RNA (section) | 1 | 1 | ||||||||
In situ reporter (knock in) | 2 | |||||||||
Western blot | 3 | |||||||||
RT-PCR | 1 |
Wwox WW domain-containing oxidoreductase (Synonyms: 5330426P09Rik, 9030416C10Rik, WOX1) | |
Results | Reference |
3* | J:138140 Aqeilan RI, Hassan MQ, de Bruin A, Hagan JP, Volinia S, Palumbo T, Hussain S, Lee SH, Gaur T, Stein GS, Lian JB, Croce CM, The WWOX tumor suppressor is essential for postnatal survival and normal bone metabolism. J Biol Chem. 2008 Aug 1;283(31):21629-39 |
3* | J:120064 Aqeilan RI, Trapasso F, Hussain S, Costinean S, Marshall D, Pekarsky Y, Hagan JP, Zanesi N, Kaou M, Stein GS, Lian JB, Croce CM, Targeted deletion of Wwox reveals a tumor suppressor function. Proc Natl Acad Sci U S A. 2007 Mar 6;104(10):3949-54 |
2 | J:112701 Bailey PJ, Klos JM, Andersson E, Karlen M, Kallstrom M, Ponjavic J, Muhr J, Lenhard B, Sandelin A, Ericson J, A global genomic transcriptional code associated with CNS-expressed genes. Exp Cell Res. 2006 Oct 1;312(16):3108-19 |
11* | J:89992 Chen ST, Chuang JI, Wang JP, Tsai MS, Li H, Chang NS, Expression of WW domain-containing oxidoreductase WOX1 in the developing murine nervous system. Neuroscience. 2004;124(4):831-9 |
1 | J:299855 Cheng YY, Chou YT, Lai FJ, Jan MS, Chang TH, Jou IM, Chen PS, Lo JY, Huang SS, Chang NS, Liou YT, Hsu PC, Cheng HC, Lin YS, Hsu LJ, Wwox deficiency leads to neurodevelopmental and degenerative neuropathies and glycogen synthase kinase 3beta-mediated epileptic seizure activity in mice. Acta Neuropathol Commun. 2020 Jan 30;8(1):6 |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 11/19/2024 MGI 6.24 |
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