Gene Expression Literature Summary

• Symbol: Pum2
• Name: pumilio RNA-binding family member 2
• ID: MGI:1931751

19 matching records from 19 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.

Age	E0.5	E1	E2	E2.5	E3	E3.5	E4.5	E6.5	E7.5	E8.5	E9	E9.5	E11.5	E13	E13.5	E14.5	E15	E15.5	E16.5	E18.5	E19	P
Immunohistochemistry (section)													1	1								2
In situ RNA (section)																2						1
Immunohistochemistry (whole mount)				1		1	1
In situ RNA (whole mount)										1		1
In situ reporter (knock in)						1		1	1	1												1
Northern blot																						1
Western blot						1									2			2	1	1		4
RT-PCR	1	1	1	1	1			1							1		2			1	1	7
cDNA clones										1	1

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Pum2  pumilio RNA-binding family member 2   (Synonyms: 5730503J23Rik, mKIAA0235, Pumm2)
Results	Reference
2	J:158581 Barrios F, Filipponi D, Pellegrini M, Paronetto MP, Di Siena S, Geremia R, Rossi P, De Felici M, Jannini EA, Dolci S, Opposing effects of retinoic acid and FGF9 on Nanos2 expression and meiotic entry of mouse germ cells. J Cell Sci. 2010 Mar 15;123(Pt 6):871-80
1*	J:313619 Bedogni F, Hevner RF, Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development. Front Mol Neurosci. 2021;14:686034
1	J:170300 Chen J, Melton C, Suh N, Oh JS, Horner K, Xie F, Sette C, Blelloch R, Conti M, Genome-wide analysis of translation reveals a critical role for deleted in azoospermia-like (Dazl) at the oocyte-to-zygote transition. Genes Dev. 2011 Apr 1;25(7):755-66
1*	J:153498 Diez-Roux G, Banfi S, Sultan M, Geffers L, Anand S, Rozado D, Magen A, Canidio E, Pagani M, Peluso I, Lin-Marq N, Koch M, Bilio M, Cantiello I, Verde R, De Masi C, Bianchi SA, Cicchini J, Perroud E, Mehmeti S, Dagand E, Schrinner S, Nurnberger A, SchmidtK, Metz K, Zwingmann C, Brieske N, Springer C, Hernandez AM, Herzog S, Grabbe F, Sieverding C, Fischer B, Schrader K, Brockmeyer M, Dettmer S, Helbig C, Alunni V, Battaini MA, Mura C, Henrichsen CN, Garcia-Lopez R, Echevarria D, Puelles E, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
3*	J:186646 Ekdahl Y, Farahani HS, Behm M, Lagergren J, Ohman M, A-to-I editing of microRNAs in the mammalian brain increases during development. Genome Res. 2012 Aug;22(8):1477-87
1*	J:228563 Koscielny G, Yaikhom G, Iyer V, Meehan TF, Morgan H, Atienza-Herrero J, Blake A, Chen CK, Easty R, Di Fenza A, Fiegel T, Grifiths M, Horne A, Karp NA, Kurbatova N, Mason JC, Matthews P, Oakley DJ, Qazi A, Regnart J, Retha A, Santos LA, Sneddon DJ, Warren J, Westerberg H, Wilson RJ, Melvin DG, Smedley D, Brown SD, Flicek P, Skarnes WC, Mallon AM, Parkinson H, The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data. Nucleic Acids Res. 2014 Jan;42(Database issue):D802-9
1*	J:317272 Kuc CA, Brott JT, Thorpe HHA, Smart A, Vessey JP, Staufen 1 is expressed by neural precursor cells in the developing murine cortex but is dispensable for NPC self-renewal and neuronal differentiation in vitro. Brain Res. 2021 Dec 15;1773:147700
2	J:185949 Licatalosi DD, Yano M, Fak JJ, Mele A, Grabinski SE, Zhang C, Darnell RB, Ptbp2 represses adult-specific splicing to regulate the generation of neuronal precursors in the embryonic brain. Genes Dev. 2012 Jul 15;26(14):1626-42
12	J:270950 Lin K, Zhang S, Shi Q, Zhu M, Gao L, Xia W, Geng B, Zheng Z, Xu EY, Essential requirement of mammalian Pumilio family in embryonic development. Mol Biol Cell. 2018 Nov 26;29(24):2922-2932
4	J:236329 Mak W, Fang C, Holden T, Dratver MB, Lin H, An Important Role of Pumilio 1 in Regulating the Development of the Mammalian Female Germline. Biol Reprod. 2016 Jun;94(6):134
2*	J:103446 McKee AE, Minet E, Stern C, Riahi S, Stiles CD, Silver PA, A genome-wide in situ hybridization map of RNA-binding proteins reveals anatomically restricted expression in the developing mouse brain. BMC Dev Biol. 2005 Jul 20;5:14
2	J:124972 Raji B, Dansault A, Leemput J, de la Houssaye G, Vieira V, Kobetz A, Arbogast L, Masson C, Menasche M, Abitbol M, The RNA-binding protein Musashi-1 is produced in the developing and adult mouse eye. Mol Vis. 2007;13:1412-27
1	J:230058 Suzuki A, Niimi Y, Shinmyozu K, Zhou Z, Kiso M, Saga Y, Dead end1 is an essential partner of NANOS2 for selective binding of target RNAs in male germ cell development. EMBO Rep. 2016 Jan;17(1):37-46
6	J:290083 Uyhazi KE, Yang Y, Liu N, Qi H, Huang XA, Mak W, Weatherbee SD, de Prisco N, Gennarino VA, Song X, Lin H, Pumilio proteins utilize distinct regulatory mechanisms to achieve complementary functions required for pluripotency and embryogenesis. Proc Natl Acad Sci U S A. 2020 Apr 7;117(14):7851-7862
1	J:306368 Vessey JP, Amadei G, Burns SE, Kiebler MA, Kaplan DR, Miller FD, An asymmetrically localized Staufen2-dependent RNA complex regulates maintenance of mammalian neural stem cells. Cell Stem Cell. 2012 Oct 5;11(4):517-28
3*	J:75821 White EK, Moore-Jarrett T, Ruley HE, PUM2, a novel murine puf protein, and its consensus RNA-binding site. RNA. 2001 Dec;7(12):1855-66
2	J:162904 Yamaji M, Tanaka T, Shigeta M, Chuma S, Saga Y, Saitou M, Functional reconstruction of NANOS3 expression in the germ cell lineage by a novel transgenic reporter reveals distinct subcellular localizations of NANOS3. Reproduction. 2010 Feb;139(2):381-93
1*	J:235839 Zagore LL, Grabinski SE, Sweet TJ, Hannigan MM, Sramkoski RM, Li Q, Licatalosi DD, RNA Binding Protein Ptbp2 Is Essential for Male Germ Cell Development. Mol Cell Biol. 2015 Dec;35(23):4030-42
3	J:244911 Zhang M, Chen D, Xia J, Han W, Cui X, Neuenkirchen N, Hermes G, Sestan N, Lin H, Post-transcriptional regulation of mouse neurogenesis by Pumilio proteins. Genes Dev. 2017 Jul 1;31(13):1354-1369