Symbol Name ID |
Kat5
K(lysine) acetyltransferase 5 MGI:1932051 |
Age | E7 | E7.5 | E8.5 | E9 | E9.5 | E10 | E10.5 | E11 | E11.5 | E12.5 | E14.5 | E15 | E15.5 | P |
Immunohistochemistry (section) | 1 | 1 | ||||||||||||
In situ RNA (section) | 1 | 1 | 1 | 1 | 1 | |||||||||
In situ RNA (whole mount) | 1 | 1 | 1 | 1 | ||||||||||
In situ reporter (knock in) | 1 | |||||||||||||
Northern blot | 1 | 1 | 1 | 1 | 3 | |||||||||
Western blot | 1 | |||||||||||||
RT-PCR | 1 | 1 | 1 | 1 | 1 | 1 | 1 |
Kat5 K(lysine) acetyltransferase 5 (Synonyms: Htatip, mHTATIP/CPLA2, PLIP, Tip60) | |
Results | Reference |
7* | J:278470 Acharya D, Nera B, Milstone ZJ, Bourke L, Yoon Y, Rivera-Perez JA, Trivedi CM, Fazzio TG, TIP55, a splice isoform of the KAT5 acetyltransferase, is essential for developmental gene regulation and organogenesis. Sci Rep. 2018 Oct 8;8(1):14908 |
1* | J:338182 Gehlen-Breitbach S, Schmid T, Frob F, Rodrian G, Weider M, Wegner M, Golz L, The Tip60/Ep400 chromatin remodeling complex impacts basic cellular functions in cranial neural crest-derived tissue during early orofacial development. Int J Oral Sci. 2023 Apr 6;15(1):16 |
1* | J:173071 Hattori T, Coustry F, Stephens S, Eberspaecher H, Takigawa M, Yasuda H, de Crombrugghe B, Transcriptional regulation of chondrogenesis by coactivator Tip60 via chromatin association with Sox9 and Sox5. Nucleic Acids Res. 2008 May;36(9):3011-24 |
1 | J:256001 Jung EM, Moffat JJ, Liu J, Dravid SM, Gurumurthy CB, Kim WY, Arid1b haploinsufficiency disrupts cortical interneuron development and mouse behavior. Nat Neurosci. 2017 Dec;20(12):1694-1707 |
1* | J:228563 Koscielny G, Yaikhom G, Iyer V, Meehan TF, Morgan H, Atienza-Herrero J, Blake A, Chen CK, Easty R, Di Fenza A, Fiegel T, Grifiths M, Horne A, Karp NA, Kurbatova N, Mason JC, Matthews P, Oakley DJ, Qazi A, Regnart J, Retha A, Santos LA, Sneddon DJ, Warren J, Westerberg H, Wilson RJ, Melvin DG, Smedley D, Brown SD, Flicek P, Skarnes WC, Mallon AM, Parkinson H, The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data. Nucleic Acids Res. 2014 Jan;42(Database issue):D802-9 |
4* | J:77074 McAllister D, Merlo X, Lough J, Characterization and expression of the mouse tat interactive protein 60 kD (TIP60) gene. Gene. 2002 May 1;289(1-2):169-76 |
8* | J:121832 Thomas T, Loveland KL, Voss AK, The genes coding for the MYST family histone acetyltransferases, Tip60 and Mof, are expressed at high levels during sperm development. Gene Expr Patterns. 2007 Jun;7(6):657-65 |
1 | J:333324 Tominaga K, Sakashita E, Kasashima K, Kuroiwa K, Nagao Y, Iwamori N, Endo H, Tip60/KAT5 Histone Acetyltransferase Is Required for Maintenance and Neurogenesis of Embryonic Neural Stem Cells. Int J Mol Sci. 2023 Jan 20;24(3) |
1* | J:122989 Visel A, Thaller C, Eichele G, GenePaint.org: an atlas of gene expression patterns in the mouse embryo. Nucleic Acids Res. 2004 Jan 1;32(Database issue):D552-6 |
1* | J:150467 Xie W, Dolzhanskaya N, LaFauci G, Dobkin C, Denman RB, Tissue and developmental regulation of fragile X mental retardation 1 exon 12 and 15 isoforms. Neurobiol Dis. 2009 Jul;35(1):52-62 |
1* | J:270211 Yang P, Xu C, Reece EA, Chen X, Zhong J, Zhan M, Stumpo DJ, Blackshear PJ, Yang P, Tip60- and sirtuin 2-regulated MARCKS acetylation and phosphorylation are required for diabetic embryopathy. Nat Commun. 2019 Jan 17;10(1):282 |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 11/19/2024 MGI 6.24 |
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