Symbol Name ID |
Ndel1
nudE neurodevelopment protein 1 like 1 MGI:1932915 |
Age | E0.5 | E3.5 | E7 | E7.5 | E8.5 | E10.5 | E11 | E11.5 | E12.5 | E13.5 | E14.5 | E15 | E15.5 | E16.5 | E17 | E17.5 | E18 | E18.5 | E19.5 | E | P |
Immunohistochemistry (section) | 1 | 2 | 1 | 1 | 3 | ||||||||||||||||
In situ RNA (section) | 1 | 2 | 2 | 2 | 1 | 4 | |||||||||||||||
In situ RNA (whole mount) | 1 | 1 | |||||||||||||||||||
In situ reporter (knock in) | 1 | ||||||||||||||||||||
Northern blot | 1 | 1 | 1 | 1 | 1 | 2 | |||||||||||||||
Western blot | 1 | 1 | 1 | 2 | 1 | 3 | 1 | 1 | 2 | 1 | 2 | 4 | |||||||||
RT-PCR | 1 | 1 | 1 | ||||||||||||||||||
cDNA clones | 1 |
Ndel1 nudE neurodevelopment protein 1 like 1 (Synonyms: 2600006O07Rik, mNudel) | |
Results | Reference |
1 | J:211278 Belzil C, Asada N, Ishiguro K, Nakaya T, Parsons K, Pendolino V, Neumayer G, Mapelli M, Nakatani Y, Sanada K, Nguyen MD, p600 regulates spindle orientation in apical neural progenitors and contributes to neurogenesis in the developing neocortex. Biol Open. 2014;3(6):475-85 |
3* | J:85521 Cahana A, Jin XL, Reiner O, Wynshaw-Boris A, O'Neill C, A study of the nature of embryonic lethality in LIS1-/- mice. Mol Reprod Dev. 2003 Oct;66(2):134-42 |
1* | J:153498 Diez-Roux G, Banfi S, Sultan M, Geffers L, Anand S, Rozado D, Magen A, Canidio E, Pagani M, Peluso I, Lin-Marq N, Koch M, Bilio M, Cantiello I, Verde R, De Masi C, Bianchi SA, Cicchini J, Perroud E, Mehmeti S, Dagand E, Schrinner S, Nurnberger A, SchmidtK, Metz K, Zwingmann C, Brieske N, Springer C, Hernandez AM, Herzog S, Grabbe F, Sieverding C, Fischer B, Schrader K, Brockmeyer M, Dettmer S, Helbig C, Alunni V, Battaini MA, Mura C, Henrichsen CN, Garcia-Lopez R, Echevarria D, Puelles E, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582 |
1* | J:171409 GUDMAP Consortium, GUDMAP: the GenitoUrinary Development Molecular Anatomy Project. www.gudmap.org. 2004; |
1 | J:142819 Hebbar S, Mesngon MT, Guillotte AM, Desai B, Ayala R, Smith DS, Lis1 and Ndel1 influence the timing of nuclear envelope breakdown in neural stem cells. J Cell Biol. 2008 Sep 22;182(6):1063-71 |
1* | J:71181 Ko J, Humbert S, Bronson RT, Takahashi S, Kulkarni AB, Li E, Tsai LH, p35 and p39 are essential for cyclin-dependent kinase 5 function during neurodevelopment. J Neurosci. 2001 Sep 1;21(17):6758-71 |
1* | J:228563 Koscielny G, Yaikhom G, Iyer V, Meehan TF, Morgan H, Atienza-Herrero J, Blake A, Chen CK, Easty R, Di Fenza A, Fiegel T, Grifiths M, Horne A, Karp NA, Kurbatova N, Mason JC, Matthews P, Oakley DJ, Qazi A, Regnart J, Retha A, Santos LA, Sneddon DJ, Warren J, Westerberg H, Wilson RJ, Melvin DG, Smedley D, Brown SD, Flicek P, Skarnes WC, Mallon AM, Parkinson H, The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data. Nucleic Acids Res. 2014 Jan;42(Database issue):D802-9 |
5 | J:66487 Niethammer M, Smith DS, Ayala R, Peng J, Ko J, Lee MS, Morabito M, Tsai LH, NUDEL is a novel Cdk5 substrate that associates with LIS1 and cytoplasmic dynein. Neuron. 2000 Dec;28(3):697-711 |
1* | J:219862 Okamoto M, Iguchi T, Hattori T, Matsuzaki S, Koyama Y, Taniguchi M, Komada M, Xie MJ, Yagi H, Shimizu S, Konishi Y, Omi M, Yoshimi T, Tachibana T, Fujieda S, Katayama T, Ito A, Hirotsune S, Tohyama M, Sato M, DBZ regulates cortical cell positioning and neurite development by sustaining the anterograde transport of Lis1 and DISC1 through control of Ndel1 dual-phosphorylation. J Neurosci. 2015 Feb 18;35(7):2942-58 |
2 | J:178057 Pandey JP, Smith DS, A cdk5-dependent switch regulates lis1/ndel1/dynein-driven organelle transport in adult axons. J Neurosci. 2011 Nov 23;31(47):17207-19 |
3 | J:100552 Sasaki S, Mori D, Toyo-oka K, Chen A, Garrett-Beal L, Muramatsu M, Miyagawa S, Hiraiwa N, Yoshiki A, Wynshaw-Boris A, Hirotsune S, Complete loss of Ndel1 results in neuronal migration defects and early embryonic lethality. Mol Cell Biol. 2005 Sep;25(17):7812-27 |
12 | J:66505 Sasaki S, Shionoya A, Ishida M, Gambello MJ, Yingling J, Wynshaw-Boris A, Hirotsune S, A LIS1/NUDEL/cytoplasmic dynein heavy chain complex in the developing and adult nervous system. Neuron. 2000 Dec;28(3):681-96 |
2 | J:163156 Singh KK, Ge X, Mao Y, Drane L, Meletis K, Samuels BA, Tsai LH, Dixdc1 is a critical regulator of DISC1 and embryonic cortical development. Neuron. 2010 Jul 15;67(1):33-48 |
2 | J:176963 Sumigray KD, Chen H, Lechler T, Lis1 is essential for cortical microtubule organization and desmosome stability in the epidermis. J Cell Biol. 2011 Aug 22;194(4):631-42 |
7* | J:68112 Sweeney KJ, Prokscha A, Eichele G, NudE-L, a novel Lis1-interacting protein, belongs to a family of vertebrate coiled-coil proteins. Mech Dev. 2001 Mar;101(1-2):21-33 |
2* | J:141291 Tamplin OJ, Kinzel D, Cox BJ, Bell CE, Rossant J, Lickert H, Microarray analysis of Foxa2 mutant mouse embryos reveals novel gene expression and inductive roles for the gastrula organizer and its derivatives. BMC Genomics. 2008;9(1):511 |
5* | J:215487 Thompson CL, Ng L, Menon V, Martinez S, Lee CK, Glattfelder K, Sunkin SM, Henry A, Lau C, Dang C, Garcia-Lopez R, Martinez-Ferre A, Pombero A, Rubenstein JL, Wakeman WB, Hohmann J, Dee N, Sodt AJ, Young R, Smith K, Nguyen TN, Kidney J, Kuan L, Jeromin A,Kaykas A, Miller J, Page D, Orta G, Bernard A, Riley Z, Smith S, Wohnoutka P, Hawrylycz MJ, Puelles L, Jones AR, A high-resolution spatiotemporal atlas of gene expression of the developing mouse brain. Neuron. 2014 Jul 16;83(2):309-23 |
2 | J:102751 Toyo-Oka K, Sasaki S, Yano Y, Mori D, Kobayashi T, Toyoshima YY, Tokuoka SM, Ishii S, Shimizu T, Muramatsu M, Hiraiwa N, Yoshiki A, Wynshaw-Boris A, Hirotsune S, Recruitment of katanin p60 by phosphorylated NDEL1, an LIS1 interacting protein, is essential for mitotic cell division and neuronal migration. Hum Mol Genet. 2005 Nov 1;14(21):3113-28 |
1 | J:216299 Toyo-oka K, Wachi T, Hunt RF, Baraban SC, Taya S, Ramshaw H, Kaibuchi K, Schwarz QP, Lopez AF, Wynshaw-Boris A, 14-3-3epsilon and zeta regulate neurogenesis and differentiation of neuronal progenitor cells in the developing brain. J Neurosci. 2014 Sep 3;34(36):12168-81 |
1* | J:122989 Visel A, Thaller C, Eichele G, GenePaint.org: an atlas of gene expression patterns in the mouse embryo. Nucleic Acids Res. 2004 Jan 1;32(Database issue):D552-6 |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 08/02/2024 MGI 6.24 |
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