Gene Expression Literature Summary

• Symbol: Chrdl1
• Name: chordin-like 1
• ID: MGI:1933172

21 matching records from 21 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.

Age	E7	E7.5	E8	E8.5	E9	E9.5	E10	E10.5	E11	E11.5	E12.5	E13	E13.5	E15	E15.5	E16	E16.5	E17	E17.5	E18.5	P
Immunohistochemistry (section)													1		1				1
In situ RNA (section)				2	1	5		2		1	2	1	1		1		1		1	1	3
In situ RNA (whole mount)	1	1		1		4	1	1
Northern blot	1								1					1				1			2
RT-PCR			1		1	3	1	1	1	1		1	3			1				1	6
cDNA clones											1								1

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Chrdl1  chordin-like 1   (Synonyms: CHL1, Nrln1, ventroptin-alpha, verntroptin-beta, VOPT)
Results	Reference
2	J:196086 Appler JM, Lu CC, Druckenbrod NR, Yu WM, Koundakjian EJ, Goodrich LV, Gata3 is a critical regulator of cochlear wiring. J Neurosci. 2013 Feb 20;33(8):3679-91
1	J:317270 Bottasso Arias N, Leesman L, Burra K, Snowball J, Shah RM, Mohanakrishnan M, Xu Y, Sinner D, BMP4 and WNT signaling interact to promote mouse tracheal mesenchyme morphogenesis. Am J Physiol Lung Cell Mol Physiol. 2021 Dec 1;
8*	J:66485 Coffinier C, Tran U, Larrain J, De Robertis EM, Neuralin-1 is a novel Chordin-related molecule expressed in the mouse neural plate. Mech Dev. 2001 Jan;100(1):119-22
2	J:335088 Escuin S, Rose Raza-Knight S, Savery D, Gaston-Massuet C, Galea GL, Greene NDE, Copp AJ, Dual mechanism underlying failure of neural tube closure in the Zic2 mutant mouse. Dis Model Mech. 2023 Mar 1;16(3)
1	J:192165 Forsman CL, Ng BC, Heinze RK, Kuo C, Sergi C, Gopalakrishnan R, Yee D, Graf D, Schwertfeger KL, Petryk A, BMP-binding protein twisted gastrulation is required in mammary gland epithelium for normal ductal elongation and myoepithelial compartmentalization. Dev Biol. 2013 Jan 1;373(1):95-106
3	J:186019 Gaughwin P, Ciesla M, Yang H, Lim B, Brundin P, Stage-specific modulation of cortical neuronal development by Mmu-miR-134. Cereb Cortex. 2011 Aug;21(8):1857-69
1	J:261899 Hasten E, McDonald-McGinn DM, Crowley TB, Zackai E, Emanuel BS, Morrow BE, Racedo SE, Dysregulation of TBX1 dosage in the anterior heart field results in congenital heart disease resembling the 22q11.2 duplication syndrome. Hum Mol Genet. 2018 Jun 1;27(11):1847-1857
2	J:254511 Inoue K, Hirose M, Inoue H, Hatanaka Y, Honda A, Hasegawa A, Mochida K, Ogura A, The Rodent-Specific MicroRNA Cluster within the Sfmbt2 Gene Is Imprinted and Essential for Placental Development. Cell Rep. 2017 May 2;19(5):949-956
1	J:232147 Isbel L, Srivastava R, Oey H, Spurling A, Daxinger L, Puthalakath H, Whitelaw E, Trim33 Binds and Silences a Class of Young Endogenous Retroviruses in the Mouse Testis; a Novel Component of the Arms Race between Retrotransposons and the Host Genome. PLoS Genet. 2015 Dec;11(12):e1005693
6	J:213620 Kong P, Racedo SE, Macchiarulo S, Hu Z, Carpenter C, Guo T, Wang T, Zheng D, Morrow BE, Tbx1 is required autonomously for cell survival and fate in the pharyngeal core mesoderm to form the muscles of mastication. Hum Mol Genet. 2014 Aug 15;23(16):4215-31
1	J:356545 Li X, Madison BB, Zacharias W, Kolterud A, States D, Gumucio DL, Deconvoluting the intestine: molecular evidence for a major role of the mesenchyme in the modulation of signaling cross talk. Physiol Genomics. 2007 May 11;29(3):290-301
1	J:187983 Lopez-Escobar B, De Felipe B, Sanchez-Alcazar JA, Sasaki T, Copp AJ, Ybot-Gonzalez P, Laminin and integrin expression in the ventral ectodermal ridge of the mouse embryo: Implications for regulation of BMP signalling. Dev Dyn. 2012 Nov;241(11):1808-15
1*	J:193822 Lumayag S, Haldin CE, Corbett NJ, Wahlin KJ, Cowan C, Turturro S, Larsen PE, Kovacs B, Witmer PD, Valle D, Zack DJ, Nicholson DA, Xu S, Inactivation of the microRNA-183/96/182 cluster results in syndromic retinal degeneration. Proc Natl Acad Sci U S A. 2013 Feb 5;110(6):E507-16
1	J:262487 Murgai A, Altmeyer S, Wiegand S, Tylzanowski P, Stricker S, Cooperation of BMP and IHH signaling in interdigital cell fate determination. PLoS One. 2018;13(5):e0197535
14*	J:69274 Nakayama N, Han CE, Scully S, Nishinakamura R, He C, Zeni L, Yamane H, Chang D, Yu D, Yokota T, Wen D, A novel chordin-like protein inhibitor for bone morphogenetic proteins expressed preferentially in mesenchymal cell lineages. Dev Biol. 2001 Apr 15;232(2):372-87
1*	J:87049 Nakayama N, Han CY, Cam L, Lee JI, Pretorius J, Fisher S, Rosenfeld R, Scully S, Nishinakamura R, Duryea D, Van G, Bolon B, Yokota T, Zhang K, A novel chordin-like BMP inhibitor, CHL2, expressed preferentially in chondrocytes of developing cartilage and osteoarthritic joint cartilage. Development. 2004 Jan;131(1):229-40
1	J:242314 Racedo SE, Hasten E, Lin M, Devakanmalai GS, Guo T, Ozbudak EM, Cai CL, Zheng D, Morrow BE, Reduced dosage of beta-catenin provides significant rescue of cardiac outflow tract anomalies in a Tbx1 conditional null mouse model of 22q11.2 deletion syndrome. PLoS Genet. 2017 Mar;13(3):e1006687
10	J:131661 Rizzolio F, Bione S, Sala C, Tribioli C, Ciccone R, Zuffardi O, di Iorgi N, Maghnie M, Toniolo D, Highly conserved non-coding sequences and the 18q critical region for short stature: a common mechanism of disease?. PLoS One. 2008;3(1):e1460
4	J:124256 Ybot-Gonzalez P, Gaston-Massuet C, Girdler G, Klingensmith J, Arkell R, Greene ND, Copp AJ, Neural plate morphogenesis during mouse neurulation is regulated by antagonism of Bmp signalling. Development. 2007 Sep;134(17):3203-11
1*	J:141243 Zakin L, Metzinger CA, Chang EY, Coffinier C, De Robertis EM, Development of the vertebral morphogenetic field in the mouse: interactions between Crossveinless-2 and Twisted Gastrulation. Dev Biol. 2008 Nov 1;323(1):6-18
1	J:197419 Zhou Y, Tanzie C, Yan Z, Chen S, Duncan M, Gaudenz K, Li H, Seidel C, Lewis B, Moran A, Libby RT, Kiernan AE, Xie T, Notch2 regulates BMP signaling and epithelial morphogenesis in the ciliary body of the mouse eye. Proc Natl Acad Sci U S A. 2013 May 28;110(22):8966-71