Gene Expression Literature Summary

• Symbol: Tdrd1
• Name: tudor domain containing 1
• ID: MGI:1933218

25 matching records from 25 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.

Age	E6.5	E7.5	E8.5	E10.5	E11.5	E12.5	E13.5	E14.5	E15.5	E16.5	E17.5	E18	E18.5	P
Immunohistochemistry (section)					1		1		2	4	6	2	3	5
In situ RNA (section)									1					1
Northern blot														1
Western blot										1	1			3
RT-PCR	1	1	2	1	1	1	2	1	2	2			2	6

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Tdrd1  tudor domain containing 1   (Synonyms: MTR-1)
Results	Reference
1	J:155865 Aravin AA, van der Heijden GW, Castaneda J, Vagin VV, Hannon GJ, Bortvin A, Cytoplasmic compartmentalization of the fetal piRNA pathway in mice. PLoS Genet. 2009 Dec;5(12):e1000764
1*	J:164280 Bowles J, Feng CW, Spiller C, Davidson TL, Jackson A, Koopman P, FGF9 suppresses meiosis and promotes male germ cell fate in mice. Dev Cell. 2010 Sep 14;19(3):440-9
12*	J:86119 Chuma S, Hiyoshi M, Yamamoto A, Hosokawa M, Takamune K, Nakatsuji N, Mouse Tudor Repeat-1 (MTR-1) is a novel component of chromatoid bodies/nuages in male germ cells and forms a complex with snRNPs. Mech Dev. 2003 Sep;120(9):979-90
1	J:112036 Costa Y, Speed RM, Gautier P, Semple CA, Maratou K, Turner JM, Cooke HJ, Mouse MAELSTROM: the link between meiotic silencing of unsynapsed chromatin and microRNA pathway?. Hum Mol Genet. 2006 Aug 1;15(15):2324-34
1	J:342617 Dali O, D'Cruz S, Legoff L, Diba Lahmidi M, Heitz C, Merret PE, Kernanec PY, Pakdel F, Smagulova F, Transgenerational epigenetic effects imposed by neonicotinoid thiacloprid exposure. Life Sci Alliance. 2024 Feb;7(2)
1	J:184034 De Fazio S, Bartonicek N, Di Giacomo M, Abreu-Goodger C, Sankar A, Funaya C, Antony C, Moreira PN, Enright AJ, O'Carroll D, The endonuclease activity of Mili fuels piRNA amplification that silences LINE1 elements. Nature. 2011 Dec 8;480(7376):259-63
1*	J:338939 Graham-Paquin AL, Saini D, Sirois J, Hossain I, Katz MS, Zhuang QK, Kwon SY, Yamanaka Y, Bourque G, Bouchard M, Pastor WA, ZMYM2 is essential for methylation of germline genes and active transposons in embryonic development. Nucleic Acids Res. 2023 Aug 11;51(14):7314-7329
1*	J:117063 Hosokawa M, Shoji M, Kitamura K, Tanaka T, Noce T, Chuma S, Nakatsuji N, Tudor-related proteins TDRD1/MTR-1, TDRD6 and TDRD7/TRAP: domain composition, intracellular localization, and function in male germ cells in mice. Dev Biol. 2007 Jan 1;301(1):38-52
1*	J:159518 Kuramochi-Miyagawa S, Watanabe T, Gotoh K, Takamatsu K, Chuma S, Kojima-Kita K, Shiromoto Y, Asada N, Toyoda A, Fujiyama A, Totoki Y, Shibata T, Kimura T, Nakatsuji N, Noce T, Sasaki H, Nakano T, MVH in piRNA processing and gene silencing of retrotransposons. Genes Dev. 2010 May;24(9):887-92
1	J:213579 Liao HF, Chen WS, Chen YH, Kao TH, Tseng YT, Lee CY, Chiu YC, Lee PL, Lin QJ, Ching YH, Hata K, Cheng WT, Tsai MH, Sasaki H, Ho HN, Wu SC, Huang YH, Yen P, Lin SP, DNMT3L promotes quiescence in postnatal spermatogonial progenitor cells. Development. 2014 Jun;141(12):2402-13
2	J:191206 Okamura D, Maeda I, Taniguchi H, Tokitake Y, Ikeda M, Ozato K, Mise N, Abe K, Noce T, Izpisua Belmonte JC, Matsui Y, Cell cycle gene-specific control of transcription has a critical role in proliferation of primordial germ cells. Genes Dev. 2012 Nov 15;26(22):2477-82
1	J:202012 Pandey RR, Tokuzawa Y, Yang Z, Hayashi E, Ichisaka T, Kajita S, Asano Y, Kunieda T, Sachidanandam R, Chuma S, Yamanaka S, Pillai RS, Tudor domain containing 12 (TDRD12) is essential for secondary PIWI interacting RNA biogenesis in mice. Proc Natl Acad Sci U S A. 2013 Oct 8;110(41):16492-7
1	J:197673 Saxe JP, Chen M, Zhao H, Lin H, Tdrkh is essential for spermatogenesis and participates in primary piRNA biogenesis in the germline. EMBO J. 2013 Jul 3;32(13):1869-85
2*	J:277128 Shiromoto Y, Kuramochi-Miyagawa S, Nagamori I, Chuma S, Arakawa T, Nishimura T, Hasuwa H, Tachibana T, Ikawa M, Nakano T, GPAT2 is required for piRNA biogenesis, transposon silencing, and maintenance of spermatogonia in mice. Biol Reprod. 2019 Jul 1;101(1):248-256
3	J:156018 Shoji M, Tanaka T, Hosokawa M, Reuter M, Stark A, Kato Y, Kondoh G, Okawa K, Chujo T, Suzuki T, Hata K, Martin SL, Noce T, Kuramochi-Miyagawa S, Nakano T, Sasaki H, Pillai RS, Nakatsuji N, Chuma S, The TDRD9-MIWI2 complex is essential for piRNA-mediated retrotransposon silencing in the mouse male germline. Dev Cell. 2009 Dec;17(6):775-87
1	J:157579 Suzuki A, Igarashi K, Aisaki K, Kanno J, Saga Y, NANOS2 interacts with the CCR4-NOT deadenylation complex and leads to suppression of specific RNAs. Proc Natl Acad Sci U S A. 2010 Feb 23;107(8):3594-9
1	J:306454 Tan K, Kim ME, Song HW, Skarbrevik D, Babajanian E, Bedrosian TA, Gage FH, Wilkinson MF, The Rhox gene cluster suppresses germline LINE1 transposition. Proc Natl Acad Sci U S A. 2021 Jun 8;118(23):e2024785118
2	J:151086 Vagin VV, Wohlschlegel J, Qu J, Jonsson Z, Huang X, Chuma S, Girard A, Sachidanandam R, Hannon GJ, Aravin AA, Proteomic analysis of murine Piwi proteins reveals a role for arginine methylation in specifying interaction with Tudor family members. Genes Dev. 2009 Aug 1;23(15):1749-62
1	J:221349 Vourekas A, Zheng K, Fu Q, Maragkakis M, Alexiou P, Ma J, Pillai RS, Mourelatos Z, Wang PJ, The RNA helicase MOV10L1 binds piRNA precursors to initiate piRNA processing. Genes Dev. 2015 Mar 15;29(6):617-29
1	J:169934 Watanabe T, Chuma S, Yamamoto Y, Kuramochi-Miyagawa S, Totoki Y, Toyoda A, Hoki Y, Fujiyama A, Shibata T, Sado T, Noce T, Nakano T, Nakatsuji N, Lin H, Sasaki H, MITOPLD Is a Mitochondrial Protein Essential for Nuage Formation and piRNA Biogenesis in the Mouse Germline. Dev Cell. 2011 Mar 15;20(3):364-75
3*	J:188133 Xiol J, Cora E, Koglgruber R, Chuma S, Subramanian S, Hosokawa M, Reuter M, Yang Z, Berninger P, Palencia A, Benes V, Penninger J, Sachidanandam R, Pillai RS, A Role for Fkbp6 and the Chaperone Machinery in piRNA Amplification and Transposon Silencing. Mol Cell. 2012 Sep 28;47(6):970-9
11	J:170319 Yabuta Y, Ohta H, Abe T, Kurimoto K, Chuma S, Saitou M, TDRD5 is required for retrotransposon silencing, chromatoid body assembly, and spermiogenesis in mice. J Cell Biol. 2011 Mar 7;192(5):781-95
1	J:162904 Yamaji M, Tanaka T, Shigeta M, Chuma S, Saga Y, Saitou M, Functional reconstruction of NANOS3 expression in the germ cell lineage by a novel transgenic reporter reveals distinct subcellular localizations of NANOS3. Reproduction. 2010 Feb;139(2):381-93
2	J:261014 Yoshimura T, Watanabe T, Kuramochi-Miyagawa S, Takemoto N, Shiromoto Y, Kudo A, Kanai-Azuma M, Tashiro F, Miyazaki S, Katanaya A, Chuma S, Miyazaki JI, Mouse GTSF1 is an essential factor for secondary piRNA biogenesis. EMBO Rep. 2018 Apr;19(4)
1	J:244911 Zhang M, Chen D, Xia J, Han W, Cui X, Neuenkirchen N, Hermes G, Sestan N, Lin H, Post-transcriptional regulation of mouse neurogenesis by Pumilio proteins. Genes Dev. 2017 Jul 1;31(13):1354-1369