Gene Expression Literature Summary

• Symbol: Twsg1
• Name: twisted gastrulation BMP signaling modulator 1
• ID: MGI:2137520

21 matching records from 21 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.

Age	E6.5	E7	E7.5	E8	E8.5	E9	E9.5	E10	E10.5	E11.5	E12.5	E13.5	E14	E14.5	E15	E15.5	E16	E17.5	E18	E18.5	E	P
Immunohistochemistry (section)							1		1	1		1									1	1
In situ RNA (section)				1	3	2	1			1	1		1	2		2	1	2	1			3
In situ RNA (whole mount)	2	1	1	1	2	1	1	1	1					1
In situ reporter (knock in)	1		1		2	2	1		1	1		1		1								1
Northern blot			1						1		1											3
RT-PCR									1	1	1	2		2	1					1		2

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Twsg1  twisted gastrulation BMP signaling modulator 1   (Synonyms: 1810013J15Rik, 9030422N06Rik, D17Ertd403e, Tsg)
Results	Reference
1	J:173627 Billington CJ Jr, Ng B, Forsman C, Schmidt B, Bagchi A, Symer DE, Schotta G, Gopalakrishnan R, Sarver AL, Petryk A, The molecular and cellular basis of variable craniofacial phenotypes and their genetic rescue in Twisted gastrulation mutant mice. Dev Biol. 2011 Jul 1;355(1):21-31
4*	J:93300 Blackshaw S, Harpavat S, Trimarchi J, Cai L, Huang H, Kuo WP, Weber G, Lee K, Fraioli RE, Cho SH, Yung R, Asch E, Ohno-Machado L, Wong WH, Cepko CL, Genomic analysis of mouse retinal development. PLoS Biol. 2004 Oct;2(9):E247
1*	J:101679 Deltagen Inc, NIH initiative supporting placement of Deltagen, Inc. mice into public repositories. MGI Direct Data Submission. 2005;
2	J:192165 Forsman CL, Ng BC, Heinze RK, Kuo C, Sergi C, Gopalakrishnan R, Yee D, Graf D, Schwertfeger KL, Petryk A, BMP-binding protein twisted gastrulation is required in mammary gland epithelium for normal ductal elongation and myoepithelial compartmentalization. Dev Biol. 2013 Jan 1;373(1):95-106
13*	J:70514 Graf D, Timmons PM, Hitchins M, Episkopou V, Moore G, Ito T, Fujiyama A, Fisher AG, Merkenschlager M, Evolutionary conservation, developmental expression, and genomic mapping of mammalian Twisted gastrulation. Mamm Genome. 2001 Jul;12(7):554-60
1*	J:80062 Hager-Theodorides AL, Outram SV, Shah DK, Sacedon R, Shrimpton RE, Vicente A, Varas A, Crompton T, Bone morphogenetic protein 2/4 signaling regulates early thymocyte differentiation. J Immunol. 2002 Nov 15;169(10):5496-504
1	J:157259 Ikeya M, Fukushima K, Kawada M, Onishi S, Furuta Y, Yonemura S, Kitamura T, Nosaka T, Sasai Y, Cv2, functioning as a pro-BMP factor via twisted gastrulation, is required for early development of nephron precursors. Dev Biol. 2010 Jan 15;337(2):405-14
3*	J:139028 Ikeya M, Nosaka T, Fukushima K, Kawada M, Furuta Y, Kitamura T, Sasai Y, Twisted gastrulation mutation suppresses skeletal defect phenotypes in Crossveinless 2 mutant mice. Mech Dev. 2008 Sep-Oct;125(9-10):832-42
1	J:356545 Li X, Madison BB, Zacharias W, Kolterud A, States D, Gumucio DL, Deconvoluting the intestine: molecular evidence for a major role of the mesenchyme in the modulation of signaling cross talk. Physiol Genomics. 2007 May 11;29(3):290-301
6*	J:149571 MacKenzie B, Wolff R, Lowe N, Billington CJ Jr, Peterson A, Schmidt B, Graf D, Mina M, Gopalakrishnan R, Petryk A, Twisted gastrulation limits apoptosis in the distal region of the mandibular arch in mice. Dev Biol. 2009 Apr 1;328(1):13-23
1	J:144153 Melnick M, Petryk A, Abichaker G, Witcher D, Person AD, Jaskoll T, Embryonic salivary gland dysmorphogenesis in Twisted gastrulation deficient mice. Arch Oral Biol. 2006 May;51(5):433-8
1	J:204605 Minoux M, Kratochwil CF, Ducret S, Amin S, Kitazawa T, Kurihara H, Bobola N, Vilain N, Rijli FM, Mouse Hoxa2 mutations provide a model for microtia and auricle duplication. Development. 2013 Nov;140(21):4386-97
1	J:262487 Murgai A, Altmeyer S, Wiegand S, Tylzanowski P, Stricker S, Cooperation of BMP and IHH signaling in interdigital cell fate determination. PLoS One. 2018;13(5):e0197535
3*	J:82738 Nosaka T, Morita S, Kitamura H, Nakajima H, Shibata F, Morikawa Y, Kataoka Y, Ebihara Y, Kawashima T, Itoh T, Ozaki K, Senba E, Tsuji K, Makishima F, Yoshida N, Kitamura T, Mammalian twisted gastrulation is essential for skeleto-lymphogenesis. Mol Cell Biol. 2003 Apr;23(8):2969-80
1*	J:150963 Pavlinkova G, Salbaum JM, Kappen C, Maternal diabetes alters transcriptional programs in the developing embryo. BMC Genomics. 2009;10:274
1*	J:88784 Petryk A, Anderson RM, Jarcho MP, Leaf I, Carlson CS, Klingensmith J, Shawlot W, O'Connor MB, The mammalian twisted gastrulation gene functions in foregut and craniofacial development. Dev Biol. 2004 Mar 15;267(2):374-86
5*	J:117178 Schmidl M, Adam N, Surmann-Schmitt C, Hattori T, Stock M, Dietz U, de Crombrugghe B, Poschl E, von der Mark K, Twisted gastrulation modulates bone morphogenetic protein-induced collagen II and X expression in chondrocytes in vitro and in vivo. J Biol Chem. 2006 Oct 20;281(42):31790-800
2	J:239983 Walton KD, Whidden M, Kolterud A, Shoffner SK, Czerwinski MJ, Kushwaha J, Parmar N, Chandhrasekhar D, Freddo AM, Schnell S, Gumucio DL, Villification in the mouse: Bmp signals control intestinal villus patterning. Development. 2016 Feb 01;143(3):427-36
14	J:90398 Zakin L, De Robertis EM, Inactivation of mouse Twisted gastrulation reveals its role in promoting Bmp4 activity during forebrain development. Development. 2004 Jan;131(2):413-24
1*	J:141243 Zakin L, Metzinger CA, Chang EY, Coffinier C, De Robertis EM, Development of the vertebral morphogenetic field in the mouse: interactions between Crossveinless-2 and Twisted Gastrulation. Dev Biol. 2008 Nov 1;323(1):6-18
5*	J:98379 Zakin L, Reversade B, Kuroda H, Lyons KM, De Robertis EM, Sirenomelia in Bmp7 and Tsg compound mutant mice: requirement for Bmp signaling in the development of ventral posterior mesoderm. Development. 2005 May;132(10):2489-99