Gene Expression Literature Summary

• Symbol: Ric8a
• Name: RIC8 guanine nucleotide exchange factor A
• ID: MGI:2141866

10 matching records from 10 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.

Age	E0.5	E1	E5.5	E6.5	E7	E7.5	E8.5	E9.5	E10.5	E11.5	E12	E12.5	E13.5	E14.5	E18.5	P
Immunohistochemistry (section)			1	1	1	1	1							1		3
In situ RNA (section)														1		1
Immunohistochemistry (whole mount)	1	1														1
In situ RNA (whole mount)								1	1	1
In situ reporter (knock in)								1	1	1	1	2		1		2
Western blot																1
RT-PCR													1		1	2
cDNA clones												1

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Ric8a  RIC8 guanine nucleotide exchange factor A   (Synonyms: Ric8, RIC-8, synembryn)
Results	Reference
1*	J:153498 Diez-Roux G, Banfi S, Sultan M, Geffers L, Anand S, Rozado D, Magen A, Canidio E, Pagani M, Peluso I, Lin-Marq N, Koch M, Bilio M, Cantiello I, Verde R, De Masi C, Bianchi SA, Cicchini J, Perroud E, Mehmeti S, Dagand E, Schrinner S, Nurnberger A, SchmidtK, Metz K, Zwingmann C, Brieske N, Springer C, Hernandez AM, Herzog S, Grabbe F, Sieverding C, Fischer B, Schrader K, Brockmeyer M, Dettmer S, Helbig C, Alunni V, Battaini MA, Mura C, Henrichsen CN, Garcia-Lopez R, Echevarria D, Puelles E, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
3*	J:271730 Kask K, Tikker L, Ruisu K, Lulla S, Oja EM, Meier R, Raid R, Velling T, Tonissoo T, Pooga M, Targeted deletion of RIC8A in mouse neural precursor cells interferes with the development of the brain, eyes, and muscles. Dev Neurobiol. 2018 Apr;78(4):374-390
2*	J:228563 Koscielny G, Yaikhom G, Iyer V, Meehan TF, Morgan H, Atienza-Herrero J, Blake A, Chen CK, Easty R, Di Fenza A, Fiegel T, Grifiths M, Horne A, Karp NA, Kurbatova N, Mason JC, Matthews P, Oakley DJ, Qazi A, Regnart J, Retha A, Santos LA, Sneddon DJ, Warren J, Westerberg H, Wilson RJ, Melvin DG, Smedley D, Brown SD, Flicek P, Skarnes WC, Mallon AM, Parkinson H, The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data. Nucleic Acids Res. 2014 Jan;42(Database issue):D802-9
1	J:191222 Ma S, Kwon HJ, Huang Z, Ric-8a, a guanine nucleotide exchange factor for heterotrimeric G proteins, regulates bergmann glia-basement membrane adhesion during cerebellar foliation. J Neurosci. 2012 Oct 24;32(43):14979-93
1	J:70989 Miller KG, Emerson MD, McManus JR, Rand JB, RIC-8 (Synembryn): a novel conserved protein that is required for G(q)alpha signaling in the C. elegans nervous system. Neuron. 2000 Aug;27(2):289-99
2*	J:121917 Olesen C, Nyeng P, Kalisz M, Jensen TH, Moller M, Tommerup N, Byskov AG, Global gene expression analysis in fetal mouse ovaries with and without meiosis and comparison of selected genes with meiosis in the testis. Cell Tissue Res. 2007 Apr;328(1):207-21
4	J:206422 Ruisu K, Kask K, Meier R, Saare M, Raid R, Veraksits A, Karis A, Tonissoo T, Pooga M, Ablation of RIC8A function in mouse neurons leads to a severe neuromuscular phenotype and postnatal death. PLoS One. 2013;8(8):e74031
4*	J:237701 Saare M, Lulla S, Tonissoo T, Meier R, Kask K, Ruisu K, Karis A, Salumets A, Pooga M, Expression Pattern and Localization Dynamics of Guanine Nucleotide Exchange Factor RIC8 during Mouse Oogenesis. PLoS One. 2015;10(6):e0129131
6*	J:166847 Tonissoo T, Lulla S, Meier R, Saare M, Ruisu K, Pooga M, Karis A, Nucleotide exchange factor RIC-8 is indispensable in mammalian early development. Dev Dyn. 2010 Dec;239(12):3404-15
8*	J:85655 Tonissoo T, Meier R, Talts K, Plaas M, Karis A, Expression of ric-8 (synembryn) gene in the nervous system of developing and adult mouse. Gene Expr Patterns. 2003 Oct;3(5):591-4