Gene Expression Literature Summary

• Symbol: Ano1
• Name: anoctamin 1, calcium activated chloride channel
• ID: MGI:2142149

24 matching records from 24 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.

Age	E8.5	E9.5	E10.5	E11	E11.5	E12	E12.5	E13.5	E14.5	E15	E15.5	E16.5	E17.5	E18.5	E	P
Immunohistochemistry (section)							2		2			2		1		6
In situ RNA (section)	1	1	2		2	1	3	2	6	2	4	2		3		4
In situ RNA (whole mount)	1	1	5		2		5	3			1
Western blot					1				1				1			1
RT-PCR				1	1				2		1					1
cDNA clones				1											1

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Ano1  anoctamin 1, calcium activated chloride channel   (Synonyms: Tmem16a)
Results	Reference
1*	J:153498 Diez-Roux G, Banfi S, Sultan M, Geffers L, Anand S, Rozado D, Magen A, Canidio E, Pagani M, Peluso I, Lin-Marq N, Koch M, Bilio M, Cantiello I, Verde R, De Masi C, Bianchi SA, Cicchini J, Perroud E, Mehmeti S, Dagand E, Schrinner S, Nurnberger A, SchmidtK, Metz K, Zwingmann C, Brieske N, Springer C, Hernandez AM, Herzog S, Grabbe F, Sieverding C, Fischer B, Schrader K, Brockmeyer M, Dettmer S, Helbig C, Alunni V, Battaini MA, Mura C, Henrichsen CN, Garcia-Lopez R, Echevarria D, Puelles E, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
4	J:152865 Georgas K, Rumballe B, Valerius MT, Chiu HS, Thiagarajan RD, Lesieur E, Aronow BJ, Brunskill EW, Combes AN, Tang D, Taylor D, Grimmond SM, Potter SS, McMahon AP, Little MH, Analysis of early nephron patterning reveals a role for distal RV proliferation in fusion to the ureteric tip via a cap mesenchyme-derived connecting segment. Dev Biol. 2009 Aug 15;332(2):273-86
2	J:171615 Georgas KM, Chiu HS, Lesieur E, Rumballe BA, Little MH, Expression of metanephric nephron-patterning genes in differentiating mesonephric tubules. Dev Dyn. 2011 Jun;240(6):1600-12
14*	J:144232 Gritli-Linde A, Vaziri Sani F, Rock JR, Hallberg K, Iribarne D, Harfe BD, Linde A, Expression patterns of the Tmem16 gene family during cephalic development in the mouse. Gene Expr Patterns. 2009 Mar;9(3):178-91
4*	J:171409 GUDMAP Consortium, GUDMAP: the GenitoUrinary Development Molecular Anatomy Project. www.gudmap.org. 2004;
2*	J:306246 He M, Wu B, Ye W, Le DD, Sinclair AW, Padovano V, Chen Y, Li KX, Sit R, Tan M, Caplan MJ, Neff N, Jan YN, Darmanis S, Jan LY, Chloride channels regulate differentiation and barrier functions of the mammalian airway. Elife. 2020 Apr 14;9:e53085
1	J:186529 He X, Yang WC, Wen XY, Tang D, Xiao L, Han J, Yu B, Zhang W, Mei F, Late embryonic and postnatal development of interstitial cells of cajal in mouse esophagus: distribution, proliferation and kit dependence. Cells Tissues Organs. 2012;196(2):175-88
2*	J:115165 Hecht J, Seitz V, Urban M, Wagner F, Robinson PN, Stiege A, Dieterich C, Kornak U, Wilkening U, Brieske N, Zwingman C, Kidess A, Stricker S, Mundlos S, Detection of novel skeletogenesis target genes by comprehensive analysis of a Runx2(-/-) mouse model. Gene Expr Patterns. 2007 Jan;7(1-2):102-12
5	J:276557 Hong GS, Lee SH, Lee B, Choi JH, Oh SJ, Jang Y, Hwang EM, Kim H, Jung J, Kim IB, Oh U, ANO1/TMEM16A regulates process maturation in radial glial cells in the developing brain. Proc Natl Acad Sci U S A. 2019 Jun 18;116(25):12494-12499
1	J:303088 Iino S, Horiguchi S, Horiguchi K, Hashimoto T, Interstitial cells of Cajal in W(sh)/W(sh) c-kit mutant mice. J Smooth Muscle Res. 2020;56(0):58-68
1	J:285409 Li Y, Jiao J, Deficiency of TRPM2 leads to embryonic neurogenesis defects in hyperthermia. Sci Adv. 2020 Jan;6(1):eaay6350
5	J:237697 Maurya DK, Henriques T, Marini M, Pedemonte N, Galietta LJ, Rock JR, Harfe BD, Menini A, Development of the Olfactory Epithelium and Nasal Glands in TMEM16A-/- and TMEM16A+/+ Mice. PLoS One. 2015;10(6):e0129171
1	J:305858 Morarach K, Mikhailova A, Knoflach V, Memic F, Kumar R, Li W, Ernfors P, Marklund U, Diversification of molecularly defined myenteric neuron classes revealed by single-cell RNA sequencing. Nat Neurosci. 2021 Jan;24(1):34-46
2*	J:308818 Moreau MX, Saillour Y, Cwetsch AW, Pierani A, Causeret F, Single-cell transcriptomics of the early developing mouse cerebral cortex disentangle the spatial and temporal components of neuronal fate acquisition. Development. 2021 Jul 15;148(14):dev197962
1	J:331901 Muthu V, Rohacek AM, Yao Y, Rakowiecki SM, Brown AS, Zhao YT, Meyers J, Won KJ, Ramdas S, Brown CD, Peterson KA, Epstein DJ, Genomic architecture of Shh-dependent cochlear morphogenesis. Development. 2019 Sep 19;146(18)
1	J:154739 Quina LA, Wang S, Ng L, Turner EE, Brn3a and Nurr1 mediate a gene regulatory pathway for habenula development. J Neurosci. 2009 Nov 11;29(45):14309-22
7*	J:127128 Rock JR, Cecilia Lopez M, Baker HV, Harfe BD, Identification of genes expressed in the mouse limb using a novel ZPA microarray approach. Gene Expr Patterns. 2007 Dec;8(1):19-26
8*	J:138613 Rock JR, Futtner CR, Harfe BD, The transmembrane protein TMEM16A is required for normal development of the murine trachea. Dev Biol. 2008 Sep 1;321(1):141-9
4*	J:138798 Rock JR, Harfe BD, Expression of TMEM16 paralogs during murine embryogenesis. Dev Dyn. 2008 Sep;237(9):2566-74
1	J:343283 Russell NX, Burra K, Shah RM, Bottasso-Arias N, Mohanakrishnan M, Snowball J, Ediga HH, Madala SK, Sinner D, Wnt signaling regulates ion channel expression to promote smooth muscle and cartilage formation in developing mouse trachea. Am J Physiol Lung Cell Mol Physiol. 2023 Dec 1;325(6):L788-L802
1	J:212391 Uslu VV, Petretich M, Ruf S, Langenfeld K, Fonseca NA, Marioni JC, Spitz F, Long-range enhancers regulating Myc expression are required for normal facial morphogenesis. Nat Genet. 2014 Jul;46(7):753-8
1*	J:127119 Visel A, Carson J, Oldekamp J, Warnecke M, Jakubcakova V, Zhou X, Shaw CA, Alvarez-Bolado G, Eichele G, Regulatory pathway analysis by high-throughput in situ hybridization. PLoS Genet. 2007 Oct 19;3(10):1867-83
1*	J:122989 Visel A, Thaller C, Eichele G, GenePaint.org: an atlas of gene expression patterns in the mouse embryo. Nucleic Acids Res. 2004 Jan 1;32(Database issue):D552-6
6	J:331144 Yuan W, Cui CC, Li J, Xu YH, Fan CE, Chen YC, Fan HW, Hu BX, Shi MY, Sun ZY, Wang P, Ma TX, Zhang Z, Zhu MS, Chen HQ, Intracellular TMEM16A is necessary for myogenesis of skeletal muscle. iScience. 2022 Nov 18;25(11):105446