Gene Expression Literature Summary

• Symbol: Rxfp2
• Name: relaxin/insulin-like family peptide receptor 2
• ID: MGI:2153463

16 matching records from 16 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.

Age	E7	E11	E11.5	E12.5	E13.5	E14	E14.5	E15	E15.5	E16	E16.5	E17	E17.5	E18	P
Immunohistochemistry (section)							1								1
In situ RNA (section)					1		2				1		1		1
In situ RNA (whole mount)							2		1
In situ reporter (knock in)													1		2
Northern blot	1	1						1				1
RT-PCR			1	1	1	1	1			1	2			1	7

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Rxfp2  relaxin/insulin-like family peptide receptor 2   (Synonyms: Gpr106, Great, LGR8)
Results	Reference
2	J:208419 Basta JM, Robbins L, Kiefer SM, Dorsett D, Rauchman M, Sall1 balances self-renewal and differentiation of renal progenitor cells. Development. 2014 Mar;141(5):1047-58
1*	J:153498 Diez-Roux G, Banfi S, Sultan M, Geffers L, Anand S, Rozado D, Magen A, Canidio E, Pagani M, Peluso I, Lin-Marq N, Koch M, Bilio M, Cantiello I, Verde R, De Masi C, Bianchi SA, Cicchini J, Perroud E, Mehmeti S, Dagand E, Schrinner S, Nurnberger A, SchmidtK, Metz K, Zwingmann C, Brieske N, Springer C, Hernandez AM, Herzog S, Grabbe F, Sieverding C, Fischer B, Schrader K, Brockmeyer M, Dettmer S, Helbig C, Alunni V, Battaini MA, Mura C, Henrichsen CN, Garcia-Lopez R, Echevarria D, Puelles E, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
3	J:219254 Duarte C, Kobayashi Y, Kawamoto T, Moriyama K, RELAXIN enhances differentiation and matrix mineralization through Relaxin/insulin-like family peptide receptor 2 (Rxfp2) in MC3T3-E1 cells in vitro. Bone. 2014 Aug;65:92-101
4*	J:150371 Familari M, Vu D, Parry LJ, Regulation of Rxfp2 (Lgr8) expression in the mouse fetal kidney by the transcription factor Pod1 (Tcf 21). Ann N Y Acad Sci. 2009 Apr;1160:317-9
4	J:122478 Feng S, Bogatcheva NV, Truong A, Korchin B, Bishop CE, Klonisch T, Agoulnik IU, Agoulnik AI, Devlopmental Expression and gene regulations of insulin-like 3 receptor RXFP2 in mouse male reproductive organs. Biol Reprod. 2007 Oct;77(4):671-80
4*	J:79124 Gorlov IP, Kamat A, Bogatcheva NV, Jones E, Lamb DJ, Truong A, Bishop CE, McElreavey K, Agoulnik AI, Mutations of the GREAT gene cause cryptorchidism. Hum Mol Genet. 2002 Sep 15;11(19):2309-18
2*	J:171409 GUDMAP Consortium, GUDMAP: the GenitoUrinary Development Molecular Anatomy Project. www.gudmap.org. 2004;
3	J:194006 Huang Z, Rivas B, Agoulnik AI, Insulin-like 3 signaling is important for testicular descent but dispensable for spermatogenesis and germ cell survival in adult mice. Biol Reprod. 2012;87(6):143
1	J:182895 Kaftanovskaya EM, Feng S, Huang Z, Tan Y, Barbara AM, Kaur S, Truong A, Gorlov IP, Agoulnik AI, Suppression of insulin-like3 receptor reveals the role of beta-catenin and Notch signaling in gubernaculum development. Mol Endocrinol. 2011 Jan;25(1):170-83
1	J:314319 Kaftanovskaya EM, Neukirchner G, Huff V, Agoulnik AI, Left-sided cryptorchidism in mice with Wilms' tumour 1 gene deletion in gubernaculum testis. J Pathol. 2013 May;230(1):39-47
1	J:92627 Kamat AA, Feng S, Bogatcheva NV, Truong A, Bishop CE, Agoulnik AI, Genetic targeting of relaxin and insulin-like factor 3 receptors in mice. Endocrinology. 2004 Oct;145(10):4712-20
1*	J:228563 Koscielny G, Yaikhom G, Iyer V, Meehan TF, Morgan H, Atienza-Herrero J, Blake A, Chen CK, Easty R, Di Fenza A, Fiegel T, Grifiths M, Horne A, Karp NA, Kurbatova N, Mason JC, Matthews P, Oakley DJ, Qazi A, Regnart J, Retha A, Santos LA, Sneddon DJ, Warren J, Westerberg H, Wilson RJ, Melvin DG, Smedley D, Brown SD, Flicek P, Skarnes WC, Mallon AM, Parkinson H, The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data. Nucleic Acids Res. 2014 Jan;42(Database issue):D802-9
1	J:290695 Kothandapani A, Lewis SR, Noel JL, Zacharski A, Krellwitz K, Baines A, Winske S, Vezina CM, Kaftanovskaya EM, Agoulnik AI, Merton EM, Cohn MJ, Jorgensen JS, GLI3 resides at the intersection of hedgehog and androgen action to promote male sex differentiation. PLoS Genet. 2020 Jun;16(6):e1008810
2*	J:283272 Livermore C, Warr N, Chalon N, Siggers P, Mianne J, Codner G, Teboul L, Wells S, Greenfield A, Male mice lacking ADAMTS-16 are fertile but exhibit testes of reduced weight. Sci Rep. 2019 Nov 20;9(1):17195
2*	J:69948 Overbeek PA, Gorlov IP, Sutherland RW, Houston JB, Harrison WR, Boettger-Tong HL, Bishop CE, Agoulnik AI, A transgenic insertion causing cryptorchidism in mice. Genesis. 2001 May;30(1):26-35
2	J:147206 Warr N, Siggers P, Bogani D, Brixey R, Pastorelli L, Yates L, Dean CH, Wells S, Satoh W, Shimono A, Greenfield A, Sfrp1 and Sfrp2 are required for normal male sexual development in mice. Dev Biol. 2009 Feb 15;326(2):273-84