Gene Expression Literature Summary

• Symbol: Nae1
• Name: NEDD8 activating enzyme E1 subunit 1
• ID: MGI:2384561

5 matching records from 5 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.

Age	E11.5	E12.5	E14.5	E15.5	E18.5	P
In situ RNA (section)	1			1	1	1
In situ reporter (knock in)			1
Northern blot						1
Western blot		1	1	1	1	1
RT-PCR						2

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Nae1  NEDD8 activating enzyme E1 subunit 1   (Synonyms: Appbp1, MGC:29435, MGC:36437, MGC:36630)
Results	Reference
1	J:80709 Aubert J, Dunstan H, Chambers I, Smith A, Functional gene screening in embryonic stem cells implicates Wnt antagonism in neural differentiation. Nat Biotechnol. 2002 Dec;20(12):1240-5
3*	J:162220 Magdaleno S, Jensen P, Brumwell CL, Seal A, Lehman K, Asbury A, Cheung T, Cornelius T, Batten DM, Eden C, Norland SM, Rice DS, Dosooye N, Shakya S, Mehta P, Curran T, BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system. PLoS Biol. 2006 Apr;4(4):e86
2	J:299730 Zhang L, Jing H, Li H, Chen W, Luo B, Zhang H, Dong Z, Li L, Su H, Xiong WC, Mei L, Neddylation is critical to cortical development by regulating Wnt/beta-catenin signaling. Proc Natl Acad Sci U S A. 2020 Oct 20;117(42):26448-26459
6	J:261328 Zou J, Ma W, Li J, Littlejohn R, Zhou H, Kim IM, Fulton DJR, Chen W, Weintraub NL, Zhou J, Su H, Neddylation mediates ventricular chamber maturation through repression of Hippo signaling. Proc Natl Acad Sci U S A. 2018 Apr 24;115(17):E4101-E4110
1*	J:333036 Zou J, Wang W, Lu Y, Ayala J, Dong K, Zhou H, Wang J, Chen W, Weintraub NL, Zhou J, Li J, Su H, Neddylation is required for perinatal cardiac development through stimulation of metabolic maturation. Cell Rep. 2023 Jan 31;42(1):112018