Symbol Name ID |
Arhgef11
Rho guanine nucleotide exchange factor 11 MGI:2441869 |
Age | E10 | E10.5 | E12 | E13 | E16.5 | E17 | P |
Immunohistochemistry (whole mount) | 1 | 1 | |||||
In situ reporter (knock in) | 1 | ||||||
Northern blot | 1 | 1 | 1 | ||||
Western blot | 1 | ||||||
RT-PCR | 1 | 1 | 1 |
Arhgef11 Rho guanine nucleotide exchange factor 11 (Synonyms: PDZ-RhoGEF, Prg) | |
Results | Reference |
1 | J:226997 Bebee TW, Park JW, Sheridan KI, Warzecha CC, Cieply BW, Rohacek AM, Xing Y, Carstens RP, The splicing regulators Esrp1 and Esrp2 direct an epithelial splicing program essential for mammalian development. Elife. 2015;4 |
2 | J:289439 Houssin NS, Martin JB, Coppola V, Yoon SO, Plageman TF Jr, Formation and contraction of multicellular actomyosin cables facilitate lens placode invagination. Dev Biol. 2020 Jun 1;462(1):36-49 |
1* | J:228563 Koscielny G, Yaikhom G, Iyer V, Meehan TF, Morgan H, Atienza-Herrero J, Blake A, Chen CK, Easty R, Di Fenza A, Fiegel T, Grifiths M, Horne A, Karp NA, Kurbatova N, Mason JC, Matthews P, Oakley DJ, Qazi A, Regnart J, Retha A, Santos LA, Sneddon DJ, Warren J, Westerberg H, Wilson RJ, Melvin DG, Smedley D, Brown SD, Flicek P, Skarnes WC, Mallon AM, Parkinson H, The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data. Nucleic Acids Res. 2014 Jan;42(Database issue):D802-9 |
1* | J:293624 Lee S, Sears MJ, Zhang Z, Li H, Salhab I, Krebs P, Xing Y, Nah HD, Williams T, Carstens RP, Cleft lip and cleft palate in Esrp1 knockout mice is associated with alterations in epithelial-mesenchymal crosstalk. Development. 2020 Apr 30;147(21):dev187369 |
1* | J:198274 Mikelis CM, Palmby TR, Simaan M, Li W, Szabo R, Lyons R, Martin D, Yagi H, Fukuhara S, Chikumi H, Galisteo R, Mukouyama YS, Bugge TH, Gutkind JS, PDZ-RhoGEF and LARG are essential for embryonic development and provide a link between thrombin and LPA receptors and Rho activation. J Biol Chem. 2013 Apr 26;288(17):12232-43 |
1 | J:245876 Rohacek AM, Bebee TW, Tilton RK, Radens CM, McDermott-Roe C, Peart N, Kaur M, Zaykaner M, Cieply B, Musunuru K, Barash Y, Germiller JA, Krantz ID, Carstens RP, Epstein DJ, ESRP1 Mutations Cause Hearing Loss due to Defects in Alternative Splicing that Disrupt Cochlear Development. Dev Cell. 2017 Nov 06;43(3):318-331.e5 |
3* | J:84356 Yoshizawa M, Sone M, Matsuo N, Nagase T, Ohara O, Nabeshima Y, Hoshino M, Dynamic and coordinated expression profile of dbl-family guanine nucleotide exchange factors in the developing mouse brain. Gene Expr Patterns. 2003 Jun;3(3):375-81 |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 11/12/2024 MGI 6.24 |
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