Gene Expression Literature Summary

• Symbol: Cnot1
• Name: CCR4-NOT transcription complex, subunit 1
• ID: MGI:2442402

12 matching records from 12 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.

Age	E3.5	E8	E8.5	E11.5	E12.5	E13	E14.5	E15	E15.5	E17	E	P
Immunohistochemistry (section)									1
In situ RNA (section)			1	1			2		1			1
In situ RNA (whole mount)	1	1	1
Western blot					1	1		1	3	1	1	2
RT-PCR					1

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Cnot1  CCR4-NOT transcription complex, subunit 1   (Synonyms: 6030411K04Rik)
Results	Reference
4*	J:174695 Chen C, Ito K, Takahashi A, Wang G, Suzuki T, Nakazawa T, Yamamoto T, Yokoyama K, Distinct expression patterns of the subunits of the CCR4-NOT deadenylase complex during neural development. Biochem Biophys Res Commun. 2011 Jul 29;411(2):360-4
2*	J:282824 Kruszka P, Berger SI, Weiss K, Everson JL, Martinez AF, Hong S, Anyane-Yeboa K, Lipinski RJ, Muenke M, A CCR4-NOT Transcription Complex, Subunit 1, CNOT1, Variant Associated with Holoprosencephaly. Am J Hum Genet. 2019 May 2;104(5):990-993
3*	J:162220 Magdaleno S, Jensen P, Brumwell CL, Seal A, Lehman K, Asbury A, Cheung T, Cornelius T, Batten DM, Eden C, Norland SM, Rice DS, Dosooye N, Shakya S, Mehta P, Curran T, BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system. PLoS Biol. 2006 Apr;4(4):e86
1	J:350444 Martinez-Mayer J, Brinkmeier ML, O'Connell SP, Ukagwu A, Marti MA, Miras M, Forclaz MV, Benzrihen MG, Cheung LYM, Camper SA, Ellsworth BS, Raetzman LT, Perez-Millan MI, Davis SW, Knockout mice with pituitary malformations help identify human cases of hypopituitarism. Genome Med. 2024 May 31;16(1):75
2	J:361793 Serdar LD, Egol JR, Lackford B, Bennett BD, Hu G, Silver DL, mRNA stability fine-tunes gene expression in the developing cortex to control neurogenesis. PLoS Biol. 2025 Feb;23(2):e3003031
3	J:157579 Suzuki A, Igarashi K, Aisaki K, Kanno J, Saga Y, NANOS2 interacts with the CCR4-NOT deadenylation complex and leads to suppression of specific RNAs. Proc Natl Acad Sci U S A. 2010 Feb 23;107(8):3594-9
1	J:230058 Suzuki A, Niimi Y, Shinmyozu K, Zhou Z, Kiso M, Saga Y, Dead end1 is an essential partner of NANOS2 for selective binding of target RNAs in male germ cell development. EMBO Rep. 2016 Jan;17(1):37-46
1	J:187029 Suzuki A, Saba R, Miyoshi K, Morita Y, Saga Y, Interaction between NANOS2 and the CCR4-NOT deadenylation complex is essential for male germ cell development in mouse. PLoS One. 2012;7(3):e33558
1*	J:272586 Suzuki T, Kikuguchi C, Nishijima S, Nagashima T, Takahashi A, Okada M, Yamamoto T, Postnatal liver functional maturation requires Cnot complex-mediated decay of mRNAs encoding cell cycle and immature liver genes. Development. 2019 Feb 15;146(4):dev168146
1*	J:143778 Tamplin OJ, Cox BJ, Rossant J, Integrated microarray and ChIP analysis identifies multiple Foxa2 dependent target genes in the notochord. Dev Biol. 2011 Dec 15;360(2):415-25
1*	J:122989 Visel A, Thaller C, Eichele G, GenePaint.org: an atlas of gene expression patterns in the mouse embryo. Nucleic Acids Res. 2004 Jan 1;32(Database issue):D552-6
1	J:196241 Zheng X, Dumitru R, Lackford BL, Freudenberg JM, Singh AP, Archer TK, Jothi R, Hu G, Cnot1, Cnot2, and Cnot3 maintain mouse and human ESC identity and inhibit extraembryonic differentiation. Stem Cells. 2012 May;30(5):910-22