Symbol Name ID |
Thoc2
THO complex 2 MGI:2442413 |
Age | E0.5 | E1 | E2 | E2.5 | E3 | E3.5 | E14.5 | E18.5 | P |
Immunohistochemistry (whole mount) | 1 | ||||||||
Western blot | 1 | 1 | 1 | ||||||
RT-PCR | 1 | 1 | 1 | 1 | 1 | 1 | 1 |
Thoc2 THO complex 2 (Synonyms: 6330441O12Rik, D130005M13Rik, LOC382210, LOC386493) | |
Results | Reference |
4 | J:345229 Bhattacharjee R, Jolly LA, Corbett MA, Wee IC, Rao SR, Gardner AE, Ritchie T, van Hugte EJH, Ciptasari U, Piltz S, Noll JE, Nazri N, van Eyk CL, White M, Fornarino D, Poulton C, Baynam G, Collins-Praino LE, Snel MF, Nadif Kasri N, Hemsley KM, Thomas PQ, Kumar R, Gecz J, Compromised transcription-mRNA export factor THOC2 causes R-loop accumulation, DNA damage and adverse neurodevelopment. Nat Commun. 2024 Feb 8;15(1):1210 |
7* | J:204143 Wang L, Miao YL, Zheng X, Lackford B, Zhou B, Han L, Yao C, Ward JM, Burkholder A, Lipchina I, Fargo DC, Hochedlinger K, Shi Y, Williams CJ, Hu G, The THO Complex Regulates Pluripotency Gene mRNA Export and Controls Embryonic Stem Cell Self-Renewal and Somatic Cell Reprogramming. Cell Stem Cell. 2013 Dec 5;13(6):676-90 |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 12/10/2024 MGI 6.24 |
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