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Gene Expression Literature Summary
Symbol
Name
ID
Eda2r
ectodysplasin A2 receptor
MGI:2442860

12 matching records from 12 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.
Age E8.5 E9.5 E10.5 E11 E11.5 E12.5 E13.5 E14.5 E15.5 E18.5 E19 P
Immunohistochemistry (section) 1
In situ RNA (section) 1 1
Western blot 1
RT-PCR 1 2 2 1 1 1 2 2 1 1 1 1

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available
Eda2r  ectodysplasin A2 receptor   (Synonyms: 9430060M22Rik, Xedar)
Results  Reference
1J:319558 Bizen N, Bepari AK, Zhou L, Abe M, Sakimura K, Ono K, Takebayashi H, Ddx20, an Olig2 binding factor, governs the survival of neural and oligodendrocyte progenitor cells via proper Mdm2 splicing and p53 suppression. Cell Death Differ. 2022;
1J:260112 Filipova D, Henry M, Rotshteyn T, Brunn A, Carstov M, Deckert M, Hescheler J, Sachinidis A, Pfitzer G, Papadopoulos S, Distinct transcriptomic changes in E14.5 mouse skeletal muscle lacking RYR1 or Cav1.1 converge at E18.5. PLoS One. 2018;13(3):e0194428
2J:204566 Gendrel AV, Tang YA, Suzuki M, Godwin J, Nesterova TB, Greally JM, Heard E, Brockdorff N, Epigenetic functions of smchd1 repress gene clusters on the inactive X chromosome and on autosomes. Mol Cell Biol. 2013 Aug;33(16):3150-65
1J:331939 Keil JM, Doyle DZ, Qalieh A, Lam MM, Funk OH, Qalieh Y, Shi L, Mohan N, Sorel A, Kwan KY, Symmetric neural progenitor divisions require chromatin-mediated homologous recombination DNA repair by Ino80. Nat Commun. 2020 Jul 31;11(1):3839
1J:352165 Lin Y, Tang W, Huang P, Wang Z, Duan L, Jia C, Sun R, Liu L, Shen J, Denticleless E3 ubiquitin protein ligase (DTL) maintains the proliferation and differentiation of epidermis and hair follicles during skin development. Dev Dyn. 2024 Jul;253(7):635-647
6*J:87681 Newton K, French DM, Yan M, Frantz GD, Dixit VM, Myodegeneration in EDA-A2 transgenic mice is prevented by XEDAR deficiency. Mol Cell Biol. 2004 Feb;24(4):1608-13
1*J:221155 Quintens R, Verreet T, Janssen A, Neefs M, Leysen L, Michaux A, Verslegers M, Samari N, Pani G, Verheyde J, Baatout S, Benotmane MA, Identification of novel radiation-induced p53-dependent transcripts extensively regulated during mouse brain development. Biol Open. 2015;4(3):331-44
1*J:82802 Ruiz S, Segrelles C, Bravo A, Santos M, Perez P, Leis H, Jorcano JL, Paramio JM, Abnormal epidermal differentiation and impaired epithelial-mesenchymal tissue interactions in mice lacking the retinoblastoma relatives p107 and p130. Development. 2003 Jun;130(11):2341-53
1J:278483 Shi L, Qalieh A, Lam MM, Keil JM, Kwan KY, Robust elimination of genome-damaged cells safeguards against brain somatic aneuploidy following Knl1 deletion. Nat Commun. 2019 Jun 13;10(1):2588
2J:308686 Tiu GC, Kerr CH, Forester CM, Krishnarao PS, Rosenblatt HD, Raj N, Lantz TC, Zhulyn O, Bowen ME, Shokat L, Attardi LD, Ruggero D, Barna M, A p53-dependent translational program directs tissue-selective phenotypes in a model of ribosomopathies. Dev Cell. 2021 Jul 26;56(14):2089-2102.e11
2J:334712 Wark AR, Aldea D, Tomizawa RR, Kokalari B, Warder B, Kamberov YG, Ectodysplasin Signaling through XEDAR Is Required for Mammary Gland Morphogenesis. J Invest Dermatol. 2023 Feb 18;
1J:317033 Xie C, Abrams SR, Herranz-Perez V, Garcia-Verdugo JM, Reiter JF, Endoderm development requires centrioles to restrain p53-mediated apoptosis in the absence of ERK activity. Dev Cell. 2021 Dec 20;56(24):3334-3348.e6

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory