Gene Expression Literature Summary

• Symbol: Sun2
• Name: Sad1 and UNC84 domain containing 2
• ID: MGI:2443011

9 matching records from 9 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.

Age	E12.5	E13.5	E14.5	E15.5	E16.5	E18.5	P
Immunohistochemistry (section)		1	1	2		3	4
Immunohistochemistry (whole mount)							1
In situ reporter (knock in)							1
Western blot	1		1	1	1	1	3
RT-PCR						1	1

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Sun2  Sad1 and UNC84 domain containing 2   (Synonyms: B230369L08Rik, Unc84b)
Results	Reference
1*	J:304350 Carley E, Stewart RM, Zieman A, Jalilian I, King DE, Zubek A, Lin S, Horsley V, King MC, The LINC complex transmits integrin-dependent tension to the nuclear lamina and represses epidermal differentiation. Elife. 2021 Mar;:e58541
6	J:263180 Dominguez Gonzalez B, Billion K, Rous S, Pavie B, Lange C, Goodchild R, Excess LINC complexes impair brain morphogenesis in a mouse model of recessive TOR1A disease. Hum Mol Genet. 2018 Jun 15;27(12):2154-2170
1*	J:228563 Koscielny G, Yaikhom G, Iyer V, Meehan TF, Morgan H, Atienza-Herrero J, Blake A, Chen CK, Easty R, Di Fenza A, Fiegel T, Grifiths M, Horne A, Karp NA, Kurbatova N, Mason JC, Matthews P, Oakley DJ, Qazi A, Regnart J, Retha A, Santos LA, Sneddon DJ, Warren J, Westerberg H, Wilson RJ, Melvin DG, Smedley D, Brown SD, Flicek P, Skarnes WC, Mallon AM, Parkinson H, The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data. Nucleic Acids Res. 2014 Jan;42(Database issue):D802-9
4*	J:150047 Lei K, Zhang X, Ding X, Guo X, Chen M, Zhu B, Xu T, Zhuang Y, Xu R, Han M, SUN1 and SUN2 play critical but partially redundant roles in anchoring nuclei in skeletal muscle cells in mice. Proc Natl Acad Sci U S A. 2009 Jun 23;106(25):10207-12
2*	J:302139 Ramirez-Martinez A, Zhang Y, Chen K, Kim J, Cenik BK, McAnally JR, Cai C, Shelton JM, Huang J, Brennan A, Evers BM, Mammen PPA, Xu L, Bassel-Duby R, Liu N, Olson EN, The nuclear envelope protein Net39 is essential for muscle nuclear integrity and chromatin organization. Nat Commun. 2021 Jan 29;12(1):690
3	J:339839 Ross JA, Arcos-Villacis N, Battey E, Boogerd C, Orellana CA, Marhuenda E, Swiatlowska P, Hodzic D, Prin F, Mohun T, Catibog N, Tapia O, Gerace L, Iskratsch T, Shah AM, Stroud MJ, Lem2 is essential for cardiac development by maintaining nuclear integrity. Cardiovasc Res. 2023 Sep 5;119(11):2074-2088
3	J:246890 Stroud MJ, Feng W, Zhang J, Veevers J, Fang X, Gerace L, Chen J, Nesprin 1alpha2 is essential for mouse postnatal viability and nuclear positioning in skeletal muscle. J Cell Biol. 2017 Jul 03;216(7):1915-1924
1	J:168852 Yu J, Lei K, Zhou M, Craft CM, Xu G, Xu T, Zhuang Y, Xu R, Han M, KASH protein Syne-2/Nesprin-2 and SUN proteins SUN1/2 mediate nuclear migration during mammalian retinal development. Hum Mol Genet. 2011 Mar 15;20(6):1061-73
2	J:155113 Zhang X, Lei K, Yuan X, Wu X, Zhuang Y, Xu T, Xu R, Han M, SUN1/2 and Syne/Nesprin-1/2 complexes connect centrosome to the nucleus during neurogenesis and neuronal migration in mice. Neuron. 2009 Oct 29;64(2):173-87