Gene Expression Literature Summary

• Symbol: Cadps2
• Name: Ca2+-dependent activator protein for secretion 2
• ID: MGI:2443963

15 matching records from 15 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.

Age	E10.5	E11.5	E13.5	E14.5	E15.5	E16	E18	E18.5	E19	P
Immunohistochemistry (section)						1			1	5
In situ RNA (section)		1	1	1	1			1	1	9
Western blot									1	3
RT-PCR	1			1			4	1		6

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Cadps2  Ca2+-dependent activator protein for secretion 2   (Synonyms: A230044C21Rik, Caps2, cpd2)
Results	Reference
1	J:332132 Cattaneo P, Hayes MGB, Baumgarten N, Hecker D, Peruzzo S, Aslan GS, Kunderfranco P, Larcher V, Zhang L, Contu R, Fonseca G, Spinozzi S, Chen J, Condorelli G, Dimmeler S, Schulz MH, Heinz S, Guimaraes-Camboa N, Evans SM, DOT1L regulates chamber-specific transcriptional networks during cardiogenesis and mediates postnatal cell cycle withdrawal. Nat Commun. 2022 Dec 2;13(1):7444
1*	J:153498 Diez-Roux G, Banfi S, Sultan M, Geffers L, Anand S, Rozado D, Magen A, Canidio E, Pagani M, Peluso I, Lin-Marq N, Koch M, Bilio M, Cantiello I, Verde R, De Masi C, Bianchi SA, Cicchini J, Perroud E, Mehmeti S, Dagand E, Schrinner S, Nurnberger A, SchmidtK, Metz K, Zwingmann C, Brieske N, Springer C, Hernandez AM, Herzog S, Grabbe F, Sieverding C, Fischer B, Schrader K, Brockmeyer M, Dettmer S, Helbig C, Alunni V, Battaini MA, Mura C, Henrichsen CN, Garcia-Lopez R, Echevarria D, Puelles E, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
1*	J:310161 Fujima S, Yamaga R, Minami H, Mizuno S, Shinoda Y, Sadakata T, Abe M, Sakimura K, Sano Y, Furuichi T, CAPS2 Deficiency Impairs the Release of the Social Peptide Oxytocin, as Well as Oxytocin-Associated Social Behavior. J Neurosci. 2021 May 19;41(20):4524-4535
1*	J:138839 Fulp CT, Cho G, Marsh ED, Nasrallah IM, Labosky PA, Golden JA, Identification of Arx transcriptional targets in the developing basal forebrain. Hum Mol Genet. 2008;17(23):3740-60
1	J:345844 Guo Y, Xiang P, Sun X, Liu W, Zhou J, Yin B, Hou L, Qiang B, Li H, Shu P, Peng X, Docking protein 6 (DOK6) selectively docks the neurotrophic signaling transduction to restrain peripheral neuropathy. Signal Transduct Target Ther. 2024 Feb 14;9(1):32
1*	J:205051 Miller JA, Nathanson J, Franjic D, Shim S, Dalley RA, Shapouri S, Smith KA, Sunkin SM, Bernard A, Bennett JL, Lee CK, Hawrylycz MJ, Jones AR, Amaral DG, Sestan N, Gage FH, Lein ES, Conserved molecular signatures of neurogenesis in the hippocampal subgranular zone of rodents and primates. Development. 2013 Nov;140(22):4633-44
2*	J:263391 Nguyen Truong CQ, Nestvogel D, Ratai O, Schirra C, Stevens DR, Brose N, Rhee J, Rettig J, Secretory vesicle priming by CAPS is independent of its SNARE-binding MUN domain. Cell Rep. 2014 Nov 6;9(3):902-9
5	J:161693 Sadakata T, Furuichi T, Developmentally regulated Ca2+-dependent activator protein for secretion 2 (CAPS2) is involved in BDNF secretion and is associated with autism susceptibility. Cerebellum. 2009 Sep;8(3):312-22
3*	J:165469 Sadakata T, Itakura M, Kozaki S, Sekine Y, Takahashi M, Furuichi T, Differential distributions of the Ca2+ -dependent activator protein for secretion family proteins (CAPS2 and CAPS1) in the mouse brain. J Comp Neurol. 2006 Apr 20;495(6):735-53
5*	J:87385 Sadakata T, Mizoguchi A, Sato Y, Katoh-Semba R, Fukuda M, Mikoshiba K, Furuichi T, The secretory granule-associated protein CAPS2 regulates neurotrophin release and cell survival. J Neurosci. 2004 Jan 7;24(1):43-52
3*	J:121566 Sadakata T, Washida M, Furuichi T, Alternative splicing variations in mouse CAPS2: differential expression and functional properties of splicing variants. BMC Neurosci. 2007;8:25
3*	J:138696 Sato A, Sekine Y, Saruta C, Nishibe H, Morita N, Sato Y, Sadakata T, Shinoda Y, Kojima T, Furuichi T, Cerebellar development transcriptome database (CDT-DB): profiling of spatio-temporal gene expression during the postnatal development of mouse cerebellum. Neural Netw. 2008 Oct;21(8):1056-69
6*	J:99762 Speidel D, Bruederle CE, Enk C, Voets T, Varoqueaux F, Reim K, Becherer U, Fornai F, Ruggieri S, Holighaus Y, Weihe E, Bruns D, Brose N, Rettig J, CAPS1 regulates catecholamine loading of large dense-core vesicles. Neuron. 2005 Apr 7;46(1):75-88
5*	J:215487 Thompson CL, Ng L, Menon V, Martinez S, Lee CK, Glattfelder K, Sunkin SM, Henry A, Lau C, Dang C, Garcia-Lopez R, Martinez-Ferre A, Pombero A, Rubenstein JL, Wakeman WB, Hohmann J, Dee N, Sodt AJ, Young R, Smith K, Nguyen TN, Kidney J, Kuan L, Jeromin A,Kaykas A, Miller J, Page D, Orta G, Bernard A, Riley Z, Smith S, Wohnoutka P, Hawrylycz MJ, Puelles L, Jones AR, A high-resolution spatiotemporal atlas of gene expression of the developing mouse brain. Neuron. 2014 Jul 16;83(2):309-23
1	J:270598 Tiklova K, Bjorklund AK, Lahti L, Fiorenzano A, Nolbrant S, Gillberg L, Volakakis N, Yokota C, Hilscher MM, Hauling T, Holmstrom F, Joodmardi E, Nilsson M, Parmar M, Perlmann T, Single-cell RNA sequencing reveals midbrain dopamine neuron diversity emerging during mouse brain development. Nat Commun. 2019 Feb 4;10(1):581