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Gene Expression Literature Summary
Symbol
Name
ID
Sox2ot
SOX2 overlapping transcript (non-protein coding)
MGI:2444112

9 matching records from 9 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.
Age E9.5 E10 E10.5 E11 E12 E12.5 E13.5 E14.5 E15.5 E18.5 P
In situ RNA (section) 1 1 1 1 1 2
In situ RNA (whole mount) 1
Northern blot 1 1 1 1 1
RT-PCR 1 1 1 2 1 1 1 1

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available
Sox2ot  SOX2 overlapping transcript (non-protein coding)   (Synonyms: B230215L15Rik)
Results  Reference
9*J:159512 Amaral PP, Neyt C, Wilkins SJ, Askarian-Amiri ME, Sunkin SM, Perkins AC, Mattick JS, Complex architecture and regulated expression of the Sox2ot locus during vertebrate development. RNA. 2009 Nov;15(11):2013-27
1*J:313619 Bedogni F, Hevner RF, Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development. Front Mol Neurosci. 2021;14:686034
1J:303700 Cajigas I, Chakraborty A, Lynam M, Swyter KR, Bastidas M, Collens L, Luo H, Ay F, Kohtz JD, Sox2-Evf2 lncRNA-mediated mechanisms of chromosome topological control in developing forebrain. Development. 2021 Mar 15;148(6):dev197202
5J:316171 Knauss JL, Miao N, Kim SN, Nie Y, Shi Y, Wu T, Pinto HB, Donohoe ME, Sun T, Long noncoding RNA Sox2ot and transcription factor YY1 co-regulate the differentiation of cortical neural progenitors by repressing Sox2. Cell Death Dis. 2018 Jul 23;9(8):799
1*J:310878 Li PY, Li SQ, Gao SG, Dong DY, CRISPR/Cas9-mediated gene editing on Sox2ot promoter leads to its truncated expression and does not influence neural tube closure and embryonic development in mice. Biochem Biophys Res Commun. 2021 Oct 8;573:107-111
1J:191980 Mandalos N, Saridaki M, Harper JL, Kotsoni A, Yang P, Economides AN, Remboutsika E, Application of a novel strategy of engineering conditional alleles to a single exon gene, Sox2. PLoS One. 2012;7(9):e45768
2*J:260175 Messemaker TC, van Leeuwen SM, van den Berg PR, 't Jong AEJ, Palstra RJ, Hoeben RC, Semrau S, Mikkers HMM, Allele-specific repression of Sox2 through the long non-coding RNA Sox2ot. Sci Rep. 2018 Jan 10;8(1):386
1J:204277 Sauvageau M, Goff LA, Lodato S, Bonev B, Groff AF, Gerhardinger C, Sanchez-Gomez DB, Hacisuleyman E, Li E, Spence M, Liapis SC, Mallard W, Morse M, Swerdel MR, D'Ecclessis MF, Moore JC, Lai V, Gong G, Yancopoulos GD, Frendewey D, Kellis M, Hart RP, Valenzuela DM, Arlotta P, Rinn JL, Multiple knockout mouse models reveal lincRNAs are required for life and brain development. Elife. 2013;2(0):e01749
1J:245695 Tosetti V, Sassone J, Ferri ALM, Taiana M, Bedini G, Nava S, Brenna G, Di Resta C, Pareyson D, Di Giulio AM, Carelli S, Parati EA, Gorio A, Transcriptional role of androgen receptor in the expression of long non-coding RNA Sox2OT in neurogenesis. PLoS One. 2017;12(7):e0180579

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
08/02/2024
MGI 6.24
The Jackson Laboratory