Gene Expression Literature Summary

• Symbol: Setd1a
• Name: SET domain containing 1A
• ID: MGI:2446244

8 matching records from 8 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.

Age	E0.5	E1	E2	E2.5	E3	E3.5	E4.5	E5.5	E6.5	E7.5	E8.5	E9.5	E10.5	E14.5	E17.5	E	P
Immunohistochemistry (section)						1				1
In situ RNA (section)														1
Immunohistochemistry (whole mount)						1
In situ reporter (knock in)									1		1		1
Western blot															1	1
RT-PCR	3	3	3	2	3	3	1	1	1	2	2	1				1	2

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Setd1a  SET domain containing 1A   (Synonyms: KMT2F, MGC:55143, mKIAA0339)
Results	Reference
5*	J:170241 Bi Y, Lv Z, Wang Y, Hai T, Huo R, Zhou Z, Zhou Q, Sha J, WDR82, a Key Epigenetics-Related Factor, Plays a Crucial Role in Normal Early Embryonic Development in Mice. Biol Reprod. 2011 Apr;84(4):756-64
18*	J:208420 Bledau AS, Schmidt K, Neumann K, Hill U, Ciotta G, Gupta A, Torres DC, Fu J, Kranz A, Stewart AF, Anastassiadis K, The H3K4 methyltransferase Setd1a is first required at the epiblast stage, whereas Setd1b becomes essential after gastrulation. Development. 2014 Mar;141(5):1022-35
1*	J:233340 Fang L, Zhang J, Zhang H, Yang X, Jin X, Zhang L, Skalnik DG, Jin Y, Zhang Y, Huang X, Li J, Wong J, H3K4 Methyltransferase Set1a Is A Key Oct4 Coactivator Essential for Generation of Oct4 Positive Inner Cell Mass. Stem Cells. 2016 Mar;34(3):565-80
7	J:215367 Shao GB, Chen JC, Zhang LP, Huang P, Lu HY, Jin J, Gong AH, Sang JR, Dynamic patterns of histone H3 lysine 4 methyltransferases and demethylases during mouse preimplantation development. In Vitro Cell Dev Biol Anim. 2014 Aug;50(7):603-13
1*	J:122989 Visel A, Thaller C, Eichele G, GenePaint.org: an atlas of gene expression patterns in the mouse embryo. Nucleic Acids Res. 2004 Jan 1;32(Database issue):D552-6
1	J:335806 Yan L, Yin H, Mi Y, Wu Y, Zheng Y, Deficiency of Wdr60 and Wdr34 cause distinct neural tube malformation phenotypes in early embryos. Front Cell Dev Biol. 2023;11:1084245
3	J:313616 Zhang F, Zhao X, Jiang R, Wang Y, Wang X, Gu Y, Xu L, Ye J, Chen CD, Guo S, Zhang D, Zhao D, Identification of Jmjd3 as an Essential Epigenetic Regulator of Hox Gene Temporal Collinear Activation for Body Axial Patterning in Mice. Front Cell Dev Biol. 2021;9:642931
1	J:351002 Zhao T, Hong Y, Yan B, Huang S, Ming GL, Song H, Epigenetic maintenance of adult neural stem cell quiescence in the mouse hippocampus via Setd1a. Nat Commun. 2024 Jul 6;15(1):5674