Symbol Name ID |
Prdm13
PR domain containing 13 MGI:2448528 |
Age | E9 | E9.5 | E10.5 | E11.5 | E12.5 | E13.5 | E14.5 | E15.5 | E16.5 | E17.5 | E18.5 | P |
Immunohistochemistry (section) | 1 | 1 | 1 | 2 | 2 | 4 | ||||||
In situ RNA (section) | 1 | 1 | 1 | 5 | 3 | 2 | 2 | 2 | 1 | 1 | 2 | |
In situ RNA (whole mount) | 1 | 1 | ||||||||||
In situ reporter (knock in) | 1 | 1 | ||||||||||
Northern blot | 1 | |||||||||||
Western blot | 1 | 1 | ||||||||||
RT-PCR | 1 | 1 | 1 | 2 | 2 | 1 |
Prdm13 PR domain containing 13 | |
Results | Reference |
8* | J:197142 Chang JC, Meredith DM, Mayer PR, Borromeo MD, Lai HC, Ou YH, Johnson JE, Prdm13 mediates the balance of inhibitory and excitatory neurons in somatosensory circuits. Dev Cell. 2013 Apr 29;25(2):182-95 |
6 | J:257913 Goodson NB, Nahreini J, Randazzo G, Uruena A, Johnson JE, Brzezinski JA 4th, Prdm13 is required for Ebf3+ amacrine cell formation in the retina. Dev Biol. 2018 Feb 1;434(1):149-163 |
1 | J:206882 Hanotel J, Bessodes N, Thelie A, Hedderich M, Parain K, Van Driessche B, Brandao Kde O, Kricha S, Jorgensen MC, Grapin-Botton A, Serup P, Van Lint C, Perron M, Pieler T, Henningfeld KA, Bellefroid EJ, The Prdm13 histone methyltransferase encoding gene is a Ptf1a-Rbpj downstream target that suppresses glutamatergic and promotes GABAergic neuronal fate in the dorsal neural tube. Dev Biol. 2014 Feb 15;386(2):340-57 |
5* | J:144373 Kinameri E, Inoue T, Aruga J, Imayoshi I, Kageyama R, Shimogori T, Moore AW, Prdm proto-oncogene transcription factor family expression and interaction with the Notch-Hes pathway in mouse neurogenesis. PLoS One. 2008;3(12):e3859 |
3 | J:258875 Mona B, Uruena A, Kollipara RK, Ma Z, Borromeo MD, Chang JC, Johnson JE, Repression by PRDM13 is critical for generating precision in neuronal identity. Elife. 2017 Aug 29;6:e25787 |
11 | J:222242 Watanabe S, Sanuki R, Sugita Y, Imai W, Yamazaki R, Kozuka T, Ohsuga M, Furukawa T, Prdm13 regulates subtype specification of retinal amacrine interneurons and modulates visual sensitivity. J Neurosci. 2015 May 20;35(20):8004-20 |
9 | J:316423 Whittaker DE, Oleari R, Gregory LC, Le Quesne-Stabej P, Williams HJ, Torpiano JG, Formosa N, Cachia MJ, Field D, Lettieri A, Ocaka LA, Paganoni AJ, Rajabali SH, Riegman KL, De Martini LB, Chaya T, Robinson IC, Furukawa T, Cariboni A, Basson MA, Dattani MT, A recessive PRDM13 mutation results in congenital hypogonadotropic hypogonadism and cerebellar hypoplasia. J Clin Invest. 2021 Dec 15;131(24):e141587 |
1 | J:307191 Wu M, Deng Q, Lei X, Du Y, Shen Y, Elavl2 Regulates Retinal Function Via Modulating the Differentiation of Amacrine Cells Subtype. Invest Ophthalmol Vis Sci. 2021 Jun 1;62(7):1 |
1 | J:354849 Wutikeli H, Yu Y, Zhang T, Cao J, Nawy S, Shen Y, Role of Elavl-like RNA-binding protein in retinal development and signal transduction. Biochim Biophys Acta Mol Basis Dis. 2024 Sep 20;1871(1):167518 |
1 | J:287680 Yamamoto H, Kon T, Omori Y, Furukawa T, Functional and Evolutionary Diversification of Otx2 and Crx in Vertebrate Retinal Photoreceptor and Bipolar Cell Development. Cell Rep. 2020 Jan 21;30(3):658-671.e5 |
1 | J:319845 Yu H, Rubinstein M, Low MJ, Developmental single-cell transcriptomics of hypothalamic POMC neurons reveal the genetic trajectories of multiple neuropeptidergic phenotypes. Elife. 2022 Jan 19;11:e72883 |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 11/12/2024 MGI 6.24 |
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