Gene Expression Literature Summary

• Symbol: Adamts10
• Name: ADAM metallopeptidase with thrombospondin type 1 motif 10
• ID: MGI:2449112

6 matching records from 6 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.

Age	E6.5	E7	E7.5	E9.5	E10	E10.5	E11	E12.5	E13.5	E14.5	E15	E15.5	E16.5	E17	E17.5	P
In situ RNA (section)				1		1		1	1	2		1			1
In situ reporter (knock in)								1					1		1	1
Northern blot		1					1				1			1		1
RT-PCR	1		1		1									1		3
cDNA clones															1

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Adamts10  ADAM metallopeptidase with thrombospondin type 1 motif 10   (Synonyms: ZnMP)
Results	Reference
3*	J:89731 Abe K, Yuzuriha M, Sugimoto M, Ko MS, Brathwaite M, Waeltz P, Nagaraja R, Gene content of the 750-kb critical region for mouse embryonic ectoderm lethal tcl-w5. Mamm Genome. 2004 Apr;15(4):265-76
1*	J:165751 Du J, Takeuchi H, Leonhard-Melief C, Shroyer KR, Dlugosz M, Haltiwanger RS, Holdener BC, O-fucosylation of thrombospondin type 1 repeats restricts epithelial to mesenchymal transition (EMT) and maintains epiblast pluripotency during mouse gastrulation. Dev Biol. 2010 Oct 1;346(1):25-38
1	J:351385 Kaneko N, Hirai K, Oshima M, Yura K, Hattori M, Maeda N, Ohtaka-Maruyama C, ADAMTS2 promotes radial migration by activating TGF-beta signaling in the developing neocortex. EMBO Rep. 2024 Jul;25(7):3090-3115
3	J:324217 Mead TJ, Martin DR, Wang LW, Cain SA, Gulec C, Cahill E, Mauch J, Reinhardt D, Lo C, Baldock C, Apte SS, Proteolysis of fibrillin-2 microfibrils is essential for normal skeletal development. Elife. 2022 May 3;11:e71142
12*	J:95196 Somerville RP, Jungers KA, Apte SS, Discovery and characterization of a novel, widely expressed metalloprotease, ADAMTS10, and its proteolytic activation. J Biol Chem. 2004 Dec 3;279(49):51208-17
5*	J:275665 Wang LW, Kutz WE, Mead TJ, Beene LC, Singh S, Jenkins MW, Reinhardt DP, Apte SS, Adamts10 inactivation in mice leads to persistence of ocular microfibrils subsequent to reduced fibrillin-2 cleavage. Matrix Biol. 2019 Apr;77:117-128