Symbol Name ID |
Nanos3
nanos C2HC-type zinc finger 3 MGI:2675387 |
Age | E7.5 | E8.5 | E9 | E9.5 | E11 | E11.5 | E12.5 | E13 | E13.5 | E14.5 | E15 | E15.5 | E16.5 | E17 | E17.5 | E18.5 | P |
Immunohistochemistry (section) | 1 | 2 | 1 | 1 | 1 | 2 | 1 | ||||||||||
In situ RNA (section) | 1 | 1 | 1 | ||||||||||||||
In situ RNA (whole mount) | 1 | 1 | 1 | ||||||||||||||
In situ reporter (knock in) | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 2 | ||||||
Western blot | 1 | 2 | 2 | 2 | 1 | 1 | |||||||||||
RT-PCR | 1 | 1 | 1 | 2 | 4 | 1 | 2 | 3 | 2 | 1 | 1 | 1 | 1 | 3 |
Nanos3 nanos C2HC-type zinc finger 3 (Synonyms: nos3) | |
Results | Reference |
6* | J:227840 Amadei G, Zander MA, Yang G, Dumelie JG, Vessey JP, Lipshitz HD, Smibert CA, Kaplan DR, Miller FD, A Smaug2-Based Translational Repression Complex Determines the Balance between Precursor Maintenance versus Differentiation during Mammalian Neurogenesis. J Neurosci. 2015 Nov 25;35(47):15666-81 |
1* | J:313619 Bedogni F, Hevner RF, Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development. Front Mol Neurosci. 2021;14:686034 |
2 | J:335822 Capriati M, Hao C, D'Cruz SC, Monfort C, Chevrier C, Warembourg C, Smagulova F, Genome-wide analysis of sex-specific differences in the mother-child PELAGIE cohort exposed to organophosphate metabolites. Sci Rep. 2023 May 17;13(1):8003 |
1 | J:167041 Cook MS, Munger SC, Nadeau JH, Capel B, Regulation of male germ cell cycle arrest and differentiation by DND1 is modulated by genetic background. Development. 2011 Jan;138(1):23-32 |
5 | J:165736 Guerquin MJ, Duquenne C, Lahaye JB, Tourpin S, Habert R, Livera G, New testicular mechanisms involved in the prevention of fetal meiotic initiation in mice. Dev Biol. 2010 Oct 15;346(2):320-30 |
1 | J:213579 Liao HF, Chen WS, Chen YH, Kao TH, Tseng YT, Lee CY, Chiu YC, Lee PL, Lin QJ, Ching YH, Hata K, Cheng WT, Tsai MH, Sasaki H, Ho HN, Wu SC, Huang YH, Yen P, Lin SP, DNMT3L promotes quiescence in postnatal spermatogonial progenitor cells. Development. 2014 Jun;141(12):2402-13 |
1 | J:306136 Manti M, Pui HP, Edstrom S, Risal S, Lu H, Lindgren E, Ohlsson C, Jerlhag E, Benrick A, Deng Q, Stener-Victorin E, Excess of ovarian nerve growth factor impairs embryonic development and causes reproductive and metabolic dysfunction in adult female mice. FASEB J. 2020 Nov;34(11):14440-14457 |
6 | J:217384 Suzuki A, Niimi Y, Saga Y, Interaction of NANOS2 and NANOS3 with different components of the CNOT complex may contribute to the functional differences in mouse male germ cells. Biol Open. 2014;3(12):1207-16 |
7* | J:117055 Suzuki A, Tsuda M, Saga Y, Functional redundancy among Nanos proteins and a distinct role of Nanos2 during male germ cell development. Development. 2007 Jan;134(1):77-83 |
7* | J:223131 Suzuki H, Saba R, Sada A, Saga Y, The Nanos3-3'UTR is required for germ cell specific NANOS3 expression in mouse embryos. PLoS One. 2010;5(2):e9300 |
3* | J:154912 Suzuki H, Sada A, Yoshida S, Saga Y, The heterogeneity of spermatogonia is revealed by their topology and expression of marker proteins including the germ cell-specific proteins Nanos2 and Nanos3. Dev Biol. 2009 Dec 15;336(2):222-31 |
3 | J:86522 Tsuda M, Sasaoka Y, Kiso M, Abe K, Haraguchi S, Kobayashi S, Saga Y, Conserved role of nanos proteins in germ cell development. Science. 2003 Aug 29;301(5637):1239-41 |
2 | J:277545 Wang Y, Li Q, Liu C, Han F, Chen M, Zhang L, Cui X, Qin Y, Bao S, Gao F, Protein arginine methyltransferase 5 (Prmt5) is required for germ cell survival during mouse embryonic development. Biol Reprod. 2015 Apr;92(4):104 |
1 | J:301042 Wright D, Kiso M, Saga Y, Genetic and structural analysis of the in vivo functional redundancy between murine NANOS2 and NANOS3. Development. 2021 Jan 11;148(1):dev191916 |
2 | J:320746 Wu X, Wang B, Dong Z, Zhou S, Liu Z, Shi G, Cao Y, Xu Y, A NANOS3 mutation linked to protein degradation causes premature ovarian insufficiency. Cell Death Dis. 2013 Oct 3;4:e825 |
12 | J:162904 Yamaji M, Tanaka T, Shigeta M, Chuma S, Saga Y, Saitou M, Functional reconstruction of NANOS3 expression in the germ cell lineage by a novel transgenic reporter reveals distinct subcellular localizations of NANOS3. Reproduction. 2010 Feb;139(2):381-93 |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
||
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support. |
last database update 11/12/2024 MGI 6.24 |
|
|