Gene Expression Literature Summary

• Symbol: Mirlet7d
• Name: microRNA let7d
• ID: MGI:2676796

16 matching records from 16 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.

Age	E0.5	E1	E2	E2.5	E3	E3.5	E8.5	E9.5	E10.5	E11	E11.5	E12.5	E13	E13.5	E14.5	E15	E15.5	E16	E16.5	E17	E17.5	E18	E18.5	E	P
In situ RNA (section)											1			1					1						1
Western blot														1
RT-PCR	2	2	2	2	1	1	1	1	3	1	1	3	2	2	3	2	2	1	2	1	2	1	2	1	10

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Mirlet7d  microRNA let7d   (Synonyms: Mirnlet7d, mmu-let-7d)
Results	Reference
1	J:190567 Cao L, Kong LP, Yu ZB, Han SP, Bai YF, Zhu J, Hu X, Zhu C, Zhu S, Guo XR, microRNA expression profiling of the developing mouse heart. Int J Mol Med. 2012 Nov;30(5):1095-104
1	J:273987 Chen PY, Qin L, Barnes C, Charisse K, Yi T, Zhang X, Ali R, Medina PP, Yu J, Slack FJ, Anderson DG, Kotelianski V, Wang F, Tellides G, Simons M, FGF regulates TGF-beta signaling and endothelial-to-mesenchymal transition via control of let-7 miRNA expression. Cell Rep. 2012 Dec 27;2(6):1684-96
3	J:138346 Dogini DB, Ribeiro PA, Rocha C, Pereira TC, Lopes-Cendes I, MicroRNA expression profile in murine central nervous system development. J Mol Neurosci. 2008 Jul;35(3):331-7
8*	J:297771 Fairchild CLA, Cheema SK, Wong J, Hino K, Simo S, La Torre A, Let-7 regulates cell cycle dynamics in the developing cerebral cortex and retina. Sci Rep. 2019 Oct 25;9(1):15336
3	J:223798 Golden EJ, Benito-Gonzalez A, Doetzlhofer A, The RNA-binding protein LIN28B regulates developmental timing in the mammalian cochlea. Proc Natl Acad Sci U S A. 2015 Jul 21;112(29):E3864-73
1*	J:277622 Koerner MV, Chhatbar K, Webb S, Cholewa-Waclaw J, Selfridge J, De Sousa D, Skarnes B, Rosen B, Thomas M, Bottomley J, Ramires-Solis R, Lelliott C, Adams DJ, Bird A, An Orphan CpG Island Drives Expression of a let-7 miRNA Precursor with an Important Role in Mouse Development. Epigenomes. 2019 Mar;3(1):7
1	J:183008 Li Y, Taketo T, Lau YF, Isolation of fetal gonads from embryos of timed-pregnant mice for morphological and molecular studies. Methods Mol Biol. 2012;825:3-16
7	J:335513 Liu W, Chen J, Yang C, Lee KF, Lee YL, Chiu PC, Zhang Y, Duan YG, Liu K, Yeung WS, Expression of microRNA let-7 in cleavage embryos modulates cell fate determination and formation of mouse blastocysts. Biol Reprod. 2022 Dec 10;107(6):1452-1463
3	J:238411 Miyazawa H, Yamaguchi Y, Sugiura Y, Honda K, Kondo K, Matsuda F, Yamamoto T, Suematsu M, Miura M, Rewiring of embryonic glucose metabolism via suppression of PFK-1 and aldolase during mouse chorioallantoic branching. Development. 2017 Jan 01;144(1):63-73
9	J:321070 Osborne JK, Kinney MA, Han A, Akinnola KE, Yermalovich AV, Vo LT, Pearson DS, Sousa PM, Ratanasirintrawoot S, Tsanov KM, Barragan J, North TE, Metzger RJ, Daley GQ, Lin28 paralogs regulate lung branching morphogenesis. Cell Rep. 2021 Jul 20;36(3):109408
1	J:199787 Saurat N, Andersson T, Vasistha NA, Molnar Z, Livesey FJ, Dicer is required for neural stem cell multipotency and lineage progression during cerebral cortex development. Neural Dev. 2013;8:14
1	J:344338 Subramanian M, Mills WT 4th, Paranjpe MD, Onuchukwu US, Inamdar M, Maytin AR, Li X, Pomerantz JL, Meffert MK, Growth-suppressor microRNAs mediate synaptic overgrowth and behavioral deficits in Fragile X mental retardation protein deficiency. iScience. 2024 Jan 19;27(1):108676
5	J:119483 Tang F, Kaneda M, O'Carroll D, Hajkova P, Barton SC, Sun YA, Lee C, Tarakhovsky A, Lao K, Surani MA, Maternal microRNAs are essential for mouse zygotic development. Genes Dev. 2007 Mar 15;21(6):644-8
2	J:111684 Thomson JM, Newman M, Parker JS, Morin-Kensicki EM, Wright T, Hammond SM, Extensive post-transcriptional regulation of microRNAs and its implications for cancer. Genes Dev. 2006 Aug 15;20(16):2202-7
2	J:316662 Wei J, Li H, Wang S, Li T, Fan J, Liang X, Li J, Han Q, Zhu L, Fan L, Zhao RC, let-7 enhances osteogenesis and bone formation while repressing adipogenesis of human stromal/mesenchymal stem cells by regulating HMGA2. Stem Cells Dev. 2014 Jul 1;23(13):1452-63
8	J:270550 Yermalovich AV, Osborne JK, Sousa P, Han A, Kinney MA, Chen MJ, Robinton DA, Montie H, Pearson DS, Wilson SB, Combes AN, Little MH, Daley GQ, Lin28 and let-7 regulate the timing of cessation of murine nephrogenesis. Nat Commun. 2019 Jan 11;10(1):168