Gene Expression Literature Summary

• Symbol: Mir140
• Name: microRNA 140
• ID: MGI:2676825

24 matching records from 24 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.

Age	E0.5	E1	E2	E2.5	E9.5	E10	E10.5	E11	E11.5	E12	E12.5	E13	E13.5	E14	E14.5	E15	E15.5	E16	E16.5	E17	E17.5	E18	E18.5	P
In situ RNA (section)									1	1	2	1	1	1	2	1			2				1	3
In situ RNA (whole mount)					1		2		2		3		1		2		1				1
Northern blot													1
Western blot																								1
RT-PCR	1	1	1	1		1	2	1	4		3		5	1	3	1		1	1	2	1	2		9
cDNA clones											1

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Mir140  microRNA 140   (Synonyms: Mirn140, mmu-mir-140)
Results	Reference
2*	J:200017 Barritt LC, Miller JM, Scheetz LR, Gardner K, Pierce ML, Soukup GA, Rocha-Sanchez SM, Conditional deletion of the human ortholog gene Dicer1 in Pax2-Cre expression domain impairs orofacial development. Indian J Hum Genet. 2012 Sep;18(3):310-9
2	J:164021 Bremer J, O'Connor T, Tiberi C, Rehrauer H, Weis J, Aguzzi A, Ablation of Dicer from murine Schwann cells increases their proliferation while blocking myelination. PLoS One. 2010;5(8):e12450
3*	J:152495 Carraro G, El-Hashash A, Guidolin D, Tiozzo C, Turcatel G, Young BM, De Langhe SP, Bellusci S, Shi W, Parnigotto PP, Warburton D, miR-17 family of microRNAs controls FGF10-mediated embryonic lung epithelial branching morphogenesis through MAPK14 and STAT3 regulation of E-Cadherin distribution. Dev Biol. 2009 Sep 15;333(2):238-50
1	J:133461 Choi PS, Zakhary L, Choi WY, Caron S, Alvarez-Saavedra E, Miska EA, McManus M, Harfe B, Giraldez AJ, Horvitz RH, Schier AF, Dulac C, Members of the miRNA-200 family regulate olfactory neurogenesis. Neuron. 2008 Jan 10;57(1):41-55
1*	J:153498 Diez-Roux G, Banfi S, Sultan M, Geffers L, Anand S, Rozado D, Magen A, Canidio E, Pagani M, Peluso I, Lin-Marq N, Koch M, Bilio M, Cantiello I, Verde R, De Masi C, Bianchi SA, Cicchini J, Perroud E, Mehmeti S, Dagand E, Schrinner S, Nurnberger A, SchmidtK, Metz K, Zwingmann C, Brieske N, Springer C, Hernandez AM, Herzog S, Grabbe F, Sieverding C, Fischer B, Schrader K, Brockmeyer M, Dettmer S, Helbig C, Alunni V, Battaini MA, Mura C, Henrichsen CN, Garcia-Lopez R, Echevarria D, Puelles E, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
3	J:138346 Dogini DB, Ribeiro PA, Rocha C, Pereira TC, Lopes-Cendes I, MicroRNA expression profile in murine central nervous system development. J Mol Neurosci. 2008 Jul;35(3):331-7
2*	J:257616 Du J, Zhang X, Cao H, Jiang D, Wang X, Zhou W, Chen K, Zhou J, Jiang H, Ba L, MiR-194 is involved in morphogenesis of spiral ganglion neurons in inner ear by rearranging actin cytoskeleton via targeting RhoB. Int J Dev Neurosci. 2017 Dec;63:16-26
2*	J:112756 Kloosterman WP, Wienholds E, de Bruijn E, Kauppinen S, Plasterk RH, In situ detection of miRNAs in animal embryos using LNA-modified oligonucleotide probes. Nat Methods. 2006 Jan;3(1):27-9
2	J:316130 Knezevic I, Patel A, Sundaresan NR, Gupta MP, Solaro RJ, Nagalingam RS, Gupta M, A novel cardiomyocyte-enriched microRNA, miR-378, targets insulin-like growth factor 1 receptor: implications in postnatal cardiac remodeling and cell survival. J Biol Chem. 2012 Apr 13;287(16):12913-26
1	J:266580 Kobayashi T, Kozlova A, Lin28a overexpression reveals the role of Erk signaling in articular cartilage development. Development. 2018 Aug 2;145(15):dev162594
4*	J:178144 Li L, Zhu GQ, Meng T, Shi JY, Wu J, Xu X, Shi B, Biological and epidemiological evidence of interaction of infant genotypes at Rs7205289 and maternal passive smoking in cleft palate. Am J Med Genet A. 2011 Dec;155(12):2940-8
1*	J:160269 Michon F, Tummers M, Kyyronen M, Frilander MJ, Thesleff I, Tooth morphogenesis and ameloblast differentiation are regulated by micro-RNAs. Dev Biol. 2010 Apr 15;340(2):355-68
3	J:160358 Miyaki S, Sato T, Inoue A, Otsuki S, Ito Y, Yokoyama S, Kato Y, Takemoto F, Nakasa T, Yamashita S, Takada S, Lotz MK, Ueno-Kudo H, Asahara H, MicroRNA-140 plays dual roles in both cartilage development and homeostasis. Genes Dev. 2010 Jun 1;24(11):1173-85
3	J:165457 Mukhopadhyay P, Brock G, Pihur V, Webb C, Pisano MM, Greene RM, Developmental microRNA expression profiling of murine embryonic orofacial tissue. Birth Defects Res A Clin Mol Teratol. 2010 Jul;88(7):511-34
2	J:197985 Ota H, Sakurai M, Gupta R, Valente L, Wulff BE, Ariyoshi K, Iizasa H, Davuluri RV, Nishikura K, ADAR1 forms a complex with Dicer to promote microRNA processing and RNA-induced gene silencing. Cell. 2013 Apr 25;153(3):575-89
7	J:202060 Rakoczy J, Fernandez-Valverde SL, Glazov EA, Wainwright EN, Sato T, Takada S, Combes AN, Korbie DJ, Miller D, Grimmond SM, Little MH, Asahara H, Mattick JS, Taft RJ, Wilhelm D, MicroRNAs-140-5p/140-3p modulate Leydig cell numbers in the developing mouse testis. Biol Reprod. 2013 Jun;88(6):143
5	J:119483 Tang F, Kaneda M, O'Carroll D, Hajkova P, Barton SC, Sun YA, Lee C, Tarakhovsky A, Lao K, Surani MA, Maternal microRNAs are essential for mouse zygotic development. Genes Dev. 2007 Mar 15;21(6):644-8
2	J:111684 Thomson JM, Newman M, Parker JS, Morin-Kensicki EM, Wright T, Hammond SM, Extensive post-transcriptional regulation of microRNAs and its implications for cancer. Genes Dev. 2006 Aug 15;20(16):2202-7
5*	J:111442 Tuddenham L, Wheeler G, Ntounia-Fousara S, Waters J, Hajihosseini MK, Clark I, Dalmay T, The cartilage specific microRNA-140 targets histone deacetylase 4 in mouse cells. FEBS Lett. 2006 Jul 24;580(17):4214-7
4*	J:163875 Wang XR, Zhang XM, Zhen J, Zhang PX, Xu G, Jiang H, MicroRNA expression in the embryonic mouse inner ear. Neuroreport. 2010 Jun 23;21(9):611-7
4*	J:124661 Xu S, Witmer PD, Lumayag S, Kovacs B, Valle D, MicroRNA (miRNA) transcriptome of mouse retina and identification of a sensory organ-specific miRNA cluster. J Biol Chem. 2007 Aug 24;282(34):25053-66
5	J:187536 Yamashita S, Miyaki S, Kato Y, Yokoyama S, Sato T, Barrionuevo F, Akiyama H, Scherer G, Takada S, Asahara H, L-Sox5 and Sox6 proteins enhance chondrogenic miR-140 microRNA expression by strengthening dimeric Sox9 activity. J Biol Chem. 2012 Jun 22;287(26):22206-15
2	J:176426 Yang J, Qin S, Yi C, Ma G, Zhu H, Zhou W, Xiong Y, Zhu X, Wang Y, He L, Guo X, MiR-140 is co-expressed with Wwp2-C transcript and activated by Sox9 to target Sp1 in maintaining the chondrocyte proliferation. FEBS Lett. 2011 Oct 3;585(19):2992-7
7	J:224791 Yin Y, Castro AM, Hoekstra M, Yan TJ, Kanakamedala AC, Dehner LP, Hill DA, Ornitz DM, Fibroblast Growth Factor 9 Regulation by MicroRNAs Controls Lung Development and Links DICER1 Loss to the Pathogenesis of Pleuropulmonary Blastoma. PLoS Genet. 2015 May;11(5):e1005242