Gene Expression Literature Summary

• Symbol: Mir19b-2
• Name: microRNA 19b-2
• ID: MGI:2676868

18 matching records from 18 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.

Age	E0.5	E1	E2	E2.5	E6.5	E7.5	E8.5	E9.5	E10.5	E11.5	E12	E12.5	E13	E13.5	E14	E14.5	E15.5	E16.5	E17.5	E18	E18.5	P
In situ RNA (section)										2						1					1
In situ RNA (whole mount)					1	1	1	1	1	1
Northern blot										1				1			1		1			1
RT-PCR	1	1	1	1			1	1		1	1	2	1	2	1	3	3	3	2	1	1	5

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Mir19b-2  microRNA 19b-2   (Synonyms: Mirn19b, Mirn19b-2, mmu-mir-19b-2)
Results	Reference
1	J:263996 Cao H, Yu W, Li X, Wang J, Gao S, Holton NE, Eliason S, Sharp T, Amendt BA, A new plasmid-based microRNA inhibitor system that inhibits microRNA families in transgenic mice and cells: a potential new therapeutic reagent. Gene Ther. 2016 Jun;23(6):527-42
1	J:186203 Chen Z, Wu J, Yang C, Fan P, Balazs L, Jiao Y, Lu M, Gu W, Li C, Pfeffer LM, Tigyi G, Yue J, DiGeorge syndrome critical region 8 (DGCR8) protein-mediated microRNA biogenesis is essential for vascular smooth muscle cell development in mice. J Biol Chem. 2012 Jun 1;287(23):19018-28
1	J:187728 Clovis YM, Enard W, Marinaro F, Huttner WB, De Pietri Tonelli D, Convergent repression of Foxp2 3'UTR by miR-9 and miR-132 in embryonic mouse neocortex: implications for radial migration of neurons. Development. 2012 Sep;139(18):3332-42
1	J:188762 de Pontual L, Yao E, Callier P, Faivre L, Drouin V, Cariou S, Van Haeringen A, Genevieve D, Goldenberg A, Oufadem M, Manouvrier S, Munnich A, Vidigal JA, Vekemans M, Lyonnet S, Henrion-Caude A, Ventura A, Amiel J, Germline deletion of the miR-17 approximately 92 cluster causes skeletal and growth defects in humans. Nat Genet. 2011 Oct;43(10):1026-30
2	J:111626 Deo M, Yu JY, Chung KH, Tippens M, Turner DL, Detection of mammalian microRNA expression by in situ hybridization with RNA oligonucleotides. Dev Dyn. 2006 May 30;235(9):2538-2548
2*	J:176480 Eda A, Takahashi M, Fukushima T, Hohjoh H, Alteration of microRNA expression in the process of mouse brain growth. Gene. 2011 Oct 1;485(1):46-52
6*	J:180114 Jevnaker AM, Khuu C, Kjole E, Bryne M, Osmundsen H, Expression of members of the miRNA17-92 cluster during development and in carcinogenesis. J Cell Physiol. 2011 Sep;226(9):2257-66
1*	J:182447 Jiang Z, Yu N, Kuang P, Chen M, Shao F, Martin G, Chui DH, Cardoso WV, Ai X, Lu J, Trinucleotide repeat containing 6a (Tnrc6a)-mediated microRNA function is required for development of yolk sac endoderm. J Biol Chem. 2012 Feb 17;287(8):5979-87
2*	J:112756 Kloosterman WP, Wienholds E, de Bruijn E, Kauppinen S, Plasterk RH, In situ detection of miRNAs in animal embryos using LNA-modified oligonucleotide probes. Nat Methods. 2006 Jan;3(1):27-9
4*	J:186286 Li L, Shi JY, Zhu GQ, Shi B, MiR-17-92 cluster regulates cell proliferation and collagen synthesis by targeting TGFB pathway in mouse palatal mesenchymal cells. J Cell Biochem. 2012 Apr;113(4):1235-44
2*	J:279731 Liu K, Hao Q, Wei J, Li GH, Wu Y, Zhao YF, MicroRNA-19a/b-3p protect the heart from hypertension-induced pathological cardiac hypertrophy through PDE5A. J Hypertens. 2018 Sep;36(9):1847-1857
7*	J:128019 Lu Y, Thomson JM, Wong HY, Hammond SM, Hogan BL, Transgenic over-expression of the microRNA miR-17-92 cluster promotes proliferation and inhibits differentiation of lung epithelial progenitor cells. Dev Biol. 2007 Oct 15;310(2):442-53
1	J:172088 Pan Y, Balazs L, Tigyi G, Yue J, Conditional deletion of Dicer in vascular smooth muscle cells leads to the developmental delay and embryonic mortality. Biochem Biophys Res Commun. 2011 May 13;408(3):369-74
3	J:213695 Pernaute B, Spruce T, Smith KM, Sanchez-Nieto JM, Manzanares M, Cobb B, Rodriguez TA, MicroRNAs control the apoptotic threshold in primed pluripotent stem cells through regulation of BIM. Genes Dev. 2014 Sep 1;28(17):1873-8
1	J:356218 Szakats S, McAtamney A, Cross H, Wilson MJ, Sex-biased gene and microRNA expression in the developing mouse brain is associated with neurodevelopmental functions and neurological phenotypes. Biol Sex Differ. 2023 Sep 7;14(1):57
5	J:119483 Tang F, Kaneda M, O'Carroll D, Hajkova P, Barton SC, Sun YA, Lee C, Tarakhovsky A, Lao K, Surani MA, Maternal microRNAs are essential for mouse zygotic development. Genes Dev. 2007 Mar 15;21(6):644-8
3*	J:176013 Zhang ZW, Zhang LQ, Ding L, Wang F, Sun YJ, An Y, Zhao Y, Li YH, Teng CB, MicroRNA-19b downregulates insulin 1 through targeting transcription factor NeuroD1. FEBS Lett. 2011 Aug 19;585(16):2592-8
4	J:214730 Zindy F, Kawauchi D, Lee Y, Ayrault O, Ben Merzoug L, McKinnon PJ, Ventura A, Roussel MF, Role of the miR-17 approximately 92 cluster family in cerebellar and medulloblastoma development. Biol Open. 2014;3(7):597-605