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Gene Expression Literature Summary
Symbol
Name
ID
Brsk1
BR serine/threonine kinase 1
MGI:2685946

8 matching records from 8 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.
Age E7 E11 E12 E13 E13.5 E14 E15 E15.5 E16.5 E17 P
Immunohistochemistry (section) 1 1 1 1 2 1 2
In situ RNA (section) 1 1
Northern blot 1 1 1 1 2
Western blot 1 1 4
RT-PCR 1

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available
Brsk1  BR serine/threonine kinase 1   (Synonyms: LOC381979, SAD-B)
Results  Reference
5*J:154946 Alvarado-Kristensson M, Rodriguez MJ, Silio V, Valpuesta JM, Carrera AC, SADB phosphorylation of gamma-tubulin regulates centrosome duplication. Nat Cell Biol. 2009 Sep;11(9):1081-92
2J:162066 Barnes AP, Lilley BN, Pan YA, Plummer LJ, Powell AW, Raines AN, Sanes JR, Polleux F, LKB1 and SAD kinases define a pathway required for the polarization of cortical neurons. Cell. 2007 May 4;129(3):549-63
1J:330942 Chu Q, Yao C, Qi X, Stripp BR, Tang N, STK11 is required for the normal program of ciliated cell differentiation in airways. Cell Discov. 2019;5:36
4J:262055 Dhumale P, Menon S, Chiang J, Puschel AW, The loss of the kinases SadA and SadB results in early neuronal apoptosis and a reduced number of progenitors. PLoS One. 2018;13(4):e0196698
1J:134078 Hezel AF, Gurumurthy S, Granot Z, Swisa A, Chu GC, Bailey G, Dor Y, Bardeesy N, Depinho RA, Pancreatic LKB1 deletion leads to acinar polarity defects and cystic neoplasms. Mol Cell Biol. 2008 Apr;28(7):2414-25
4J:96030 Kishi M, Pan YA, Crump JG, Sanes JR, Mammalian SAD kinases are required for neuronal polarization. Science. 2005 Feb 11;307(5711):929-32
5J:201695 Lilley BN, Pan YA, Sanes JR, SAD kinases sculpt axonal arbors of sensory neurons through long- and short-term responses to neurotrophin signals. Neuron. 2013 Jul 10;79(1):39-53
2*J:315254 Zurashvili T, Cordon-Barris L, Ruiz-Babot G, Zhou X, Lizcano JM, Gomez N, Gimenez-Llort L, Bayascas JR, Interaction of PDK1 with phosphoinositides is essential for neuronal differentiation but dispensable for neuronal survival. Mol Cell Biol. 2013 Mar;33(5):1027-40

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
12/10/2024
MGI 6.24
The Jackson Laboratory