Gene Expression Literature Summary

• Symbol: Syngap1
• Name: synaptic Ras GTPase activating protein 1 homolog (rat)
• ID: MGI:3039785

12 matching records from 12 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.

Age	E8.5	E10.5	E12	E12.5	E14	E14.5	E16	E16.5	E18	E18.5	P
Immunohistochemistry (section)											2
In situ RNA (section)						1
In situ reporter (knock in)	1	1				1		1		1	1
Western blot			1		2		1		1	1	6
RT-PCR				1		1		1		1	4

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Syngap1  synaptic Ras GTPase activating protein 1 homolog (rat)   (Synonyms: Syngap)
Results	Reference
1*	J:313619 Bedogni F, Hevner RF, Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development. Front Mol Neurosci. 2021;14:686034
1	J:306456 Farini D, Cesari E, Weatheritt RJ, La Sala G, Naro C, Pagliarini V, Bonvissuto D, Medici V, Guerra M, Di Pietro C, Rizzo FR, Musella A, Carola V, Centonze D, Blencowe BJ, Marazziti D, Sette C, A Dynamic Splicing Program Ensures Proper Synaptic Connections in the Developing Cerebellum. Cell Rep. 2020 Jun 2;31(9):107703
1*	J:283039 Giralt A, Brito V, Pardo M, Rubio SE, Marion-Poll L, Martin-Ibanez R, Zamora-Moratalla A, Bosch C, Ballesteros JJ, Blasco E, Garcia-Torralba A, Pascual M, Pumarola M, Alberch J, Gines S, Martin ED, Segovia J, Soriano E, Canals JM, Helios modulates the maturation of a CA1 neuronal subpopulation required for spatial memory formation. Exp Neurol. 2020 Jan;323:113095
1	J:346895 Guo P, Lim RC, Rajawasam K, Trinh T, Sun H, Zhang H, A methylation-phosphorylation switch controls EZH2 stability and hematopoiesis. Elife. 2024 Feb 12;13
1	J:267025 Jung H, Park H, Choi Y, Kang H, Lee E, Kweon H, Roh JD, Ellegood J, Choi W, Kang J, Rhim I, Choi SY, Bae M, Kim SG, Lee J, Chung C, Yoo T, Park H, Kim Y, Ha S, Um SM, Mo S, Kwon Y, Mah W, Bae YC, Kim H, Lerch JP, Paik SB, Kim E, Sexually dimorphic behavior, neuronal activity, and gene expression in Chd8-mutant mice. Nat Neurosci. 2018 Sep;21(9):1218-1228
2	J:101084 Knuesel I, Elliott A, Chen HJ, Mansuy IM, Kennedy MB, A role for synGAP in regulating neuronal apoptosis. Eur J Neurosci. 2005 Feb;21(3):611-21
1	J:241274 Lie E, Ko JS, Choi SY, Roh JD, Cho YS, Noh R, Kim D, Li Y, Kang H, Choi TY, Nam J, Mah W, Lee D, Lee SG, Kim HM, Kim H, Choi SY, Um JW, Kang MG, Bae YC, Ko J, Kim E, SALM4 suppresses excitatory synapse development by cis-inhibiting trans-synaptic SALM3-LAR adhesion. Nat Commun. 2016 Aug 02;7:12328
6	J:97490 Porter K, Komiyama NH, Vitalis T, Kind PC, Grant SG, Differential expression of two NMDA receptor interacting proteins, PSD-95 and SynGAP during mouse development. Eur J Neurosci. 2005 Jan;21(2):351-62
1	J:282160 Su P, Lai TKY, Lee FHF, Abela AR, Fletcher PJ, Liu F, Disruption of SynGAP-dopamine D1 receptor complexes alters actin and microtubule dynamics and impairs GABAergic interneuron migration. Sci Signal. 2019 Aug 6;12(593)
1*	J:249826 Tanabe Y, Naito Y, Vasuta C, Lee AK, Soumounou Y, Linhoff MW, Takahashi H, IgSF21 promotes differentiation of inhibitory synapses via binding to neurexin2alpha. Nat Commun. 2017 Sep 01;8(1):408
3	J:89027 Tomoda T, Kim JH, Zhan C, Hatten ME, Role of Unc51.1 and its binding partners in CNS axon outgrowth. Genes Dev. 2004 Mar 1;18(5):541-58
10*	J:334714 Yang R, Feng X, Arias-Cavieres A, Mitchell RM, Polo A, Hu K, Zhong R, Qi C, Zhang RS, Westneat N, Portillo CA, Nobrega MA, Hansel C, Garcia Iii AJ, Zhang X, Upregulation of SYNGAP1 expression in mice and human neurons by redirecting alternative splicing. Neuron. 2023 Mar 3;