Gene Expression Literature Summary

• Symbol: Apcdd1
• Name: adenomatosis polyposis coli down-regulated 1
• ID: MGI:3513977

28 matching records from 28 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.

Age	E7	E8	E8.5	E9	E9.5	E10.5	E11	E11.5	E12.5	E13	E13.5	E14	E14.5	E15.5	E16	E16.5	E	P
Immunohistochemistry (section)																		1
In situ RNA (section)			1	1	2	3		3	8	1	3	1	3	6	1	1	1	2
In situ RNA (whole mount)	1	1	2		3	4	1	3	2		2		1
RT-PCR						1			4		1		2	1		1	2

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Apcdd1  adenomatosis polyposis coli down-regulated 1   (Synonyms: Drapc1, EIG180)
Results	Reference
2	J:214677 Bohnenpoll T, Trowe MO, Wojahn I, Taketo MM, Petry M, Kispert A, Canonical Wnt signaling regulates the proliferative expansion and differentiation of fibrocytes in the murine inner ear. Dev Biol. 2014 Jul 1;391(1):54-65
2	J:161813 Chilov D, Sinjushina N, Saarimaki-Vire J, Taketo MM, Partanen J, beta-Catenin regulates intercellular signalling networks and cell-type specific transcription in the developing mouse midbrain-rhombomere 1 region. PLoS One. 2010;5(6):e10881
2*	J:165759 Chiu HS, Szucsik JC, Georgas KM, Jones JL, Rumballe BA, Tang D, Grimmond SM, Lewis AG, Aronow BJ, Lessard JL, Little MH, Comparative gene expression analysis of genital tubercle development reveals a putative appendicular Wnt7 network for the epidermal differentiation. Dev Biol. 2010 Aug 15;344(2):1071-87
2	J:330505 Drake KA, Chaney C, Patel M, Das A, Bittencourt J, Cohn M, Carroll TJ, Transcription Factors YAP/TAZ and SRF Cooperate To Specify Renal Myofibroblasts in the Developing Mouse Kidney. J Am Soc Nephrol. 2022 Aug 2;
1	J:295217 Drake KA, Chaney CP, Das A, Roy P, Kwartler CS, Rakheja D, Carroll TJ, Stromal beta-catenin activation impacts nephron progenitor differentiation in the developing kidney and may contribute to Wilms tumor. Development. 2020 Jul 31;147(21):dev189597
2	J:178994 Fantauzzo KA, Christiano AM, Trps1 activates a network of secreted Wnt inhibitors and transcription factors crucial to vibrissa follicle morphogenesis. Development. 2012 Jan;139(1):203-14
1	J:152858 Garcia-Ortiz JE, Pelosi E, Omari S, Nedorezov T, Piao Y, Karmazin J, Uda M, Cao A, Cole SW, Forabosco A, Schlessinger D, Ottolenghi C, Foxl2 functions in sex determination and histogenesis throughout mouse ovary development. BMC Dev Biol. 2009;9:36
2	J:306309 Genestine M, Ambriz D, Crabtree GW, Dummer P, Molotkova A, Quintero M, Mela A, Biswas S, Feng H, Zhang C, Canoll P, Hargus G, Agalliu D, Gogos JA, Au E, Vascular-derived SPARC and SerpinE1 regulate interneuron tangential migration and accelerate functional maturation of human stem cell-derived interneurons. Elife. 2021 Apr 27;10:e56063
1	J:245873 Goddard LM, Duchemin AL, Ramalingan H, Wu B, Chen M, Bamezai S, Yang J, Li L, Morley MP, Wang T, Scherrer-Crosbie M, Frank DB, Engleka KA, Jameson SC, Morrisey EE, Carroll TJ, Zhou B, Vermot J, Kahn ML, Hemodynamic Forces Sculpt Developing Heart Valves through a KLF2-WNT9B Paracrine Signaling Axis. Dev Cell. 2017 Nov 06;43(3):274-289.e5
2*	J:171409 GUDMAP Consortium, GUDMAP: the GenitoUrinary Development Molecular Anatomy Project. www.gudmap.org. 2004;
1	J:207650 Ha TJ, Swanson DJ, Kirova R, Yeung J, Choi K, Tong Y, Chesler EJ, Goldowitz D, Genome-wide microarray comparison reveals downstream genes of Pax6 in the developing mouse cerebellum. Eur J Neurosci. 2012 Oct;36(7):2888-98
1	J:203028 Hasenpusch-Theil K, Magnani D, Amaniti EM, Han L, Armstrong D, Theil T, Transcriptional analysis of Gli3 mutants identifies Wnt target genes in the developing hippocampus. Cereb Cortex. 2012 Dec;22(12):2878-93
2*	J:115165 Hecht J, Seitz V, Urban M, Wagner F, Robinson PN, Stiege A, Dieterich C, Kornak U, Wilkening U, Brieske N, Zwingman C, Kidess A, Stricker S, Mundlos S, Detection of novel skeletogenesis target genes by comprehensive analysis of a Runx2(-/-) mouse model. Gene Expr Patterns. 2007 Jan;7(1-2):102-12
4	J:258789 Jarvinen E, Shimomura-Kuroki J, Balic A, Jussila M, Thesleff I, Mesenchymal Wnt/beta-catenin signaling limits tooth number. Development. 2018 Feb 21;145(4):dev158048
2	J:112633 Jukkola T, Lahti L, Naserke T, Wurst W, Partanen J, FGF regulated gene-expression and neuronal differentiation in the developing midbrain-hindbrain region. Dev Biol. 2006 Sep 1;297(1):141-57
13*	J:93165 Jukkola T, Sinjushina N, Partanen J, Drapc1 expression during mouse embryonic development. Gene Expr Patterns. 2004 Oct;4(6):755-62
1	J:173718 Kalamarides M, Stemmer-Rachamimov AO, Niwa-Kawakita M, Chareyre F, Taranchon E, Han ZY, Martinelli C, Lusis EA, Hegedus B, Gutmann DH, Giovannini M, Identification of a progenitor cell of origin capable of generating diverse meningioma histological subtypes. Oncogene. 2011 May 19;30(20):2333-44
4	J:188394 Kang P, Lee HK, Glasgow SM, Finley M, Donti T, Gaber ZB, Graham BH, Foster AE, Novitch BG, Gronostajski RM, Deneen B, Sox9 and NFIA coordinate a transcriptional regulatory cascade during the initiation of gliogenesis. Neuron. 2012 Apr 12;74(1):79-94
1	J:182759 Lahti L, Peltopuro P, Piepponen TP, Partanen J, Cell-autonomous FGF signaling regulates anteroposterior patterning and neuronal differentiation in the mesodiencephalic dopaminergic progenitor domain. Development. 2012 Mar;139(5):894-905
3	J:223938 Lee HK, Laug D, Zhu W, Patel JM, Ung K, Arenkiel BR, Fancy SP, Mohila C, Deneen B, Apcdd1 stimulates oligodendrocyte differentiation after white matter injury. Glia. 2015 Oct;63(10):1840-9
2*	J:119031 Lillevali K, Haugas M, Matilainen T, Pussinen C, Karis A, Salminen M, Gata3 is required for early morphogenesis and Fgf10 expression during otic development. Mech Dev. 2006 Jun;123(6):415-29
7*	J:281669 Neupane S, Sohn WJ, Gwon GJ, Kim KR, Lee S, An CH, Suh JY, Shin HI, Yamamoto H, Cho SW, Lee Y, Kim JY, The role of APCDD1 in epithelial rearrangement in tooth morphogenesis. Histochem Cell Biol. 2015 Oct;144(4):377-87
1	J:242339 Ohayon D, Garces A, Joly W, Soukkarieh C, Takagi T, Sabourin JC, Agius E, Darling DS, De Santa Barbara P, Higashi Y, Stolt CC, Hugnot JP, Richardson WD, Carroll P, Pattyn A, Onset of Spinal Cord Astrocyte Precursor Emigration from the Ventricular Zone Involves the Zeb1 Transcription Factor. Cell Rep. 2016 Nov 01;17(6):1473-1481
1	J:179841 Pacheco M, Valencia M, Caparros-Martin JA, Mulero F, Goodship JA, Ruiz-Perez VL, Evc works in chondrocytes and osteoblasts to regulate multiple aspects of growth plate development in the appendicular skeleton and cranial base. Bone. 2012 Jan;50(1):28-41
3	J:216214 Raspopovic J, Marcon L, Russo L, Sharpe J, Modeling digits. Digit patterning is controlled by a Bmp-Sox9-Wnt Turing network modulated by morphogen gradients. Science. 2014 Aug 1;345(6196):566-70
2	J:123685 Saarimaki-Vire J, Peltopuro P, Lahti L, Naserke T, Blak AA, Vogt Weisenhorn DM, Yu K, Ornitz DM, Wurst W, Partanen J, Fibroblast growth factor receptors cooperate to regulate neural progenitor properties in the developing midbrain and hindbrain. J Neurosci. 2007 Aug 8;27(32):8581-92
4	J:338889 Siguero-Alvarez M, Salguero-Jimenez A, Grego-Bessa J, de la Barrera J, MacGrogan D, Prados B, Sanchez-Saez F, Pineiro-Sabaris R, Felipe-Medina N, Torroja C, Gomez MJ, Sabater-Molina M, Escriba R, Richaud-Patin I, Iglesias-Garcia O, Sbroggio M, Callejas S, O'Regan DP, McGurk KA, Dopazo A, Giovinazzo G, Ibanez B, Monserrat L, Perez-Pomares JM, Sanchez-Cabo F, Pendas AM, Raya A, Gimeno-Blanes JR, de la Pompa JL, A Human Hereditary Cardiomyopathy Shares a Genetic Substrate With Bicuspid Aortic Valve. Circulation. 2023 Jan 3;147(1):47-65
1	J:199302 Veenvliet JV, Dos Santos MT, Kouwenhoven WM, von Oerthel L, Lim JL, van der Linden AJ, Koerkamp MJ, Holstege FC, Smidt MP, Specification of dopaminergic subsets involves interplay of En1 and Pitx3. Development. 2013 Aug;140(16):3373-84